1 Number of women with urinary incontinence Show forest plot

5

Risk Ratio (M‐H, Random, 95% CI)

Subtotals only

1.1 Bottom‐up approach

5

573

Risk Ratio (M‐H, Random, 95% CI)

2.08 [1.04, 4.14]

2 Number of women with no improvement Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

2.1 Bottom‐up approach

3

246

Risk Ratio (M‐H, Fixed, 95% CI)

1.38 [0.55, 3.46]

3 Objectve measurement of incontinence Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

3.1 Bottom‐up approach

2

188

Risk Ratio (M‐H, Fixed, 95% CI)

4.44 [2.06, 9.56]

4 Condition‐specific health measures Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

4.1 Bottom‐up approach

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

5 Duration of operation (in minutes) Show forest plot

3

Mean Difference (IV, Random, 95% CI)

Subtotals only

5.1 Bottom‐up approach

3

386

Mean Difference (IV, Random, 95% CI)

‐17.33 [‐32.09, ‐2.57]

6 Operative blood loss Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

6.1 Bottom‐up approach

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

7 Length of in‐patient stay Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

7.1 Bottom‐up approach

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

8 Major vascular or visceral injury Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

8.1 Bottom‐up approach

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

9 Vaginal wall perforation Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

9.1 Bottom‐up approach

2

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

10 Bladder or urethral perforation Show forest plot

4

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

10.1 Bottom‐up approach

4

532

Risk Ratio (M‐H, Fixed, 95% CI)

0.45 [0.15, 1.38]

11 Urinary retention and need for catheterisation Show forest plot

5

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

11.1 Bottom‐up approach

5

578

Risk Ratio (M‐H, Fixed, 95% CI)

0.87 [0.38, 1.99]

12 Infection related to use of synthetic mesh Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

12.1 Bottom‐up approach

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

2.0 [0.22, 17.89]

13 Vaginal mesh exposure Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

13.1 Bottom‐up approach

2

333

Risk Ratio (M‐H, Fixed, 95% CI)

1.37 [0.23, 8.16]

14 Mesh extrusion into the bladder or urethra Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

14.1 Bottom‐up approach

3

445

Risk Ratio (M‐H, Fixed, 95% CI)

0.76 [0.19, 3.01]

15 Long‐term pain or discomfort Show forest plot

2

329

Odds Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

15.1 Bottom‐up approach

2

329

Odds Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

16 Dyspareunia Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

16.1 Bottom‐up approach

1

59

Risk Ratio (M‐H, Fixed, 95% CI)

2.9 [0.32, 26.30]

17 De novo urgency Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

17.1 Bottom‐up approach

3

248

Risk Ratio (M‐H, Fixed, 95% CI)

2.39 [1.25, 4.56]

18 New‐onset detrusor overactivity Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

18.1 Bottom‐up approach

1

70

Risk Ratio (M‐H, Fixed, 95% CI)

0.89 [0.13, 5.98]

19 Repeat stress incontinence surgery Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

19.1 Bottom‐up approach

2

333

Risk Ratio (M‐H, Fixed, 95% CI)

2.34 [0.79, 6.92]

20 Need for any other additional or new surgical procedure to treat complications Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

20.1 Bottom‐up approach

2

333

Risk Ratio (M‐H, Fixed, 95% CI)

1.18 [0.29, 4.74]

1 Number of women with urinary incontinence Show forest plot

17

1655

Risk Ratio (M‐H, Fixed, 95% CI)

1.91 [1.53, 2.39]

1.1 Inside‐out TVTO

10

1053

Risk Ratio (M‐H, Fixed, 95% CI)

2.55 [1.94, 3.36]

1.2 Outside‐in TOT

7

602

Risk Ratio (M‐H, Fixed, 95% CI)

0.91 [0.60, 1.39]

2 Number of women with no improvement Show forest plot

5

642

Risk Ratio (M‐H, Fixed, 95% CI)

2.29 [1.29, 4.06]

2.1 Inside‐out TVT‐O

4

437

Risk Ratio (M‐H, Fixed, 95% CI)

4.80 [2.00, 11.55]

2.2 Outside‐in TOT

1

205

Risk Ratio (M‐H, Fixed, 95% CI)

0.76 [0.32, 1.82]

3 Objective measurement of incontinence Show forest plot

12

1198

Risk Ratio (M‐H, Fixed, 95% CI)

1.88 [1.49, 2.36]

3.1 Inside‐out TVT‐O

7

804

Risk Ratio (M‐H, Fixed, 95% CI)

2.91 [2.00, 4.25]

3.2 Outside‐in TOT

5

394

Risk Ratio (M‐H, Fixed, 95% CI)

1.18 [0.90, 1.55]

4 Incontinence episodes Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

4.1 Outside‐in TOT

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

5 Pad test (weights) Show forest plot

2

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

5.1 Outside‐in TOT

2

268

Mean Difference (IV, Fixed, 95% CI)

‐1.64 [‐6.24, 2.96]

6 Condition‐specific health measures Show forest plot

3

334

Std. Mean Difference (IV, Fixed, 95% CI)

0.16 [‐0.06, 0.38]

6.1 Inside‐out TVTO

2

290

Std. Mean Difference (IV, Fixed, 95% CI)

0.07 [‐0.17, 0.30]

6.2 Outside‐in TOT (UDI 6)

1

44

Std. Mean Difference (IV, Fixed, 95% CI)

0.91 [0.25, 1.56]

7 Duration of operation (minutes) Show forest plot

9

1176

Mean Difference (IV, Fixed, 95% CI)

‐1.17 [‐1.60, ‐0.75]

7.1 Inside‐out TVTO

6

759

Mean Difference (IV, Fixed, 95% CI)

‐1.06 [‐1.50, ‐0.61]

7.2 Outside‐in TOT

3

417

Mean Difference (IV, Fixed, 95% CI)

‐2.14 [‐3.43, ‐0.84]

8 Operative blood loss (mL) Show forest plot

2

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

8.1 Inside‐out TVTO

2

320

Mean Difference (IV, Fixed, 95% CI)

18.79 [3.70, 33.88]

9 Length of in‐patient stay Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

9.1 Inside‐out TVTO

1

188

Mean Difference (IV, Fixed, 95% CI)

‐0.08 [‐0.33, 0.17]

10 Major vascular or visceral injury Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

10.1 Inside‐out TVT‐O

3

460

Risk Ratio (M‐H, Fixed, 95% CI)

1.40 [0.28, 6.89]

11 Bladder or urethral perforation Show forest plot

9

961

Risk Ratio (M‐H, Fixed, 95% CI)

1.27 [0.32, 5.02]

11.1 Inside‐out TVT‐O

5

666

Risk Ratio (M‐H, Fixed, 95% CI)

2.45 [0.40, 15.09]

11.2 Outside‐in TOT

4

295

Risk Ratio (M‐H, Fixed, 95% CI)

0.21 [0.01, 4.99]

12 Vaginal wall perforation Show forest plot

6

788

Risk Ratio (M‐H, Fixed, 95% CI)

1.67 [0.41, 6.81]

12.1 Inside‐out TVT‐O

5

715

Risk Ratio (M‐H, Fixed, 95% CI)

1.67 [0.41, 6.81]

12.2 Outside‐in TOT

1

73

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

13 Urinary retention and need for catheterisation Show forest plot

15

1477

Risk Ratio (M‐H, Random, 95% CI)

0.57 [0.28, 1.15]

13.1 Inside‐out TVTO

10

996

Risk Ratio (M‐H, Random, 95% CI)

0.72 [0.34, 1.52]

13.2 Outside‐in TOT

5

481

Risk Ratio (M‐H, Random, 95% CI)

0.51 [0.08, 3.44]

14 Infection related to use of synthetic mesh Show forest plot

2

412

Risk Ratio (M‐H, Fixed, 95% CI)

0.49 [0.09, 2.69]

14.1 Inside‐out TVT‐O

1

188

Risk Ratio (M‐H, Fixed, 95% CI)

2.88 [0.12, 69.72]

14.2 Outside‐in TOT

1

224

Risk Ratio (M‐H, Fixed, 95% CI)

0.14 [0.01, 2.73]

15 Vaginal mesh exposure Show forest plot

9

819

Risk Ratio (M‐H, Fixed, 95% CI)

2.59 [1.21, 5.56]

15.1 Inside‐out TVT‐O

5

562

Risk Ratio (M‐H, Fixed, 95% CI)

3.75 [1.42, 9.86]

15.2 Outside‐in TOT

4

257

Risk Ratio (M‐H, Fixed, 95% CI)

1.07 [0.27, 4.28]

16 Mesh extrusion into the bladder or urethra Show forest plot

2

146

Risk Ratio (M‐H, Fixed, 95% CI)

17.79 [1.06, 298.88]

16.1 Inside‐out TVT‐O

1

86

Risk Ratio (M‐H, Fixed, 95% CI)

17.79 [1.06, 298.88]

16.2 Outside‐in TOT

1

60

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

17 Postoperative pain or discomfort Show forest plot

9

1102

Risk Ratio (M‐H, Fixed, 95% CI)

0.26 [0.19, 0.37]

17.1 Inside‐out TVTO

8

806

Risk Ratio (M‐H, Fixed, 95% CI)

0.29 [0.20, 0.43]

17.2 Outside‐in TOT

2

296

Risk Ratio (M‐H, Fixed, 95% CI)

0.19 [0.09, 0.40]

18 Long‐term pain or discomfort Show forest plot

5

351

Risk Ratio (M‐H, Fixed, 95% CI)

0.14 [0.04, 0.54]

18.1 Inside‐out TVT‐O

3

235

Risk Ratio (M‐H, Fixed, 95% CI)

0.17 [0.03, 1.07]

18.2 Outside‐in TOT

2

116

Risk Ratio (M‐H, Fixed, 95% CI)

0.12 [0.02, 0.82]

19 De novo urgency Show forest plot

10

927

Risk Ratio (M‐H, Fixed, 95% CI)

1.41 [0.98, 2.03]

19.1 Inside‐out TVT‐O

8

835

Risk Ratio (M‐H, Fixed, 95% CI)

1.31 [0.90, 1.90]

19.2 Outside‐in TOT

2

92

Risk Ratio (M‐H, Fixed, 95% CI)

5.15 [0.68, 39.23]

20 Repeat stress incontinence surgery Show forest plot

6

764

Risk Ratio (M‐H, Fixed, 95% CI)

3.09 [1.48, 6.49]

20.1 Inside‐out TVT‐O

3

420

Risk Ratio (M‐H, Fixed, 95% CI)

5.86 [2.00, 17.21]

20.2 Outside‐in TOT

3

344

Risk Ratio (M‐H, Fixed, 95% CI)

1.0 [0.31, 3.18]

21 Need for any other additional or new surgical procedure to treat complications Show forest plot

8

989

Risk Ratio (M‐H, Fixed, 95% CI)

2.03 [1.09, 3.78]

21.1 Inside‐out TVT‐O

5

645

Risk Ratio (M‐H, Fixed, 95% CI)

2.15 [1.04, 4.43]

21.2 Outside‐in TOT

3

344

Risk Ratio (M‐H, Fixed, 95% CI)

1.75 [0.52, 5.85]

1 Number of women with urinary incontinence Show forest plot

6

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

1.1 TVT‐SECUR versus MiniArc

2

170

Risk Ratio (M‐H, Fixed, 95% CI)

1.11 [0.95, 1.29]

1.2 U‐type versus H‐type TVT‐Secur

3

496

Risk Ratio (M‐H, Fixed, 95% CI)

1.04 [0.78, 1.40]

1.3 MiniArc versus Ajust

1

63

Risk Ratio (M‐H, Fixed, 95% CI)

2.91 [0.63, 13.32]

2 Number of women with no improvement Show forest plot

4

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

2.1 TVT‐Secur versus MiniArc

2

170

Risk Ratio (M‐H, Fixed, 95% CI)

3.25 [0.84, 12.66]

2.2 U‐type versus H‐type TVT‐Secur

1

129

Risk Ratio (M‐H, Fixed, 95% CI)

0.74 [0.33, 1.63]

2.3 MiniArc versus Ajust

1

61

Risk Ratio (M‐H, Fixed, 95% CI)

2.21 [0.21, 23.08]

3 Objectve measurement of incontinence Show forest plot

4

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

3.1 MiniArc versus Ajust

1

63

Risk Ratio (M‐H, Fixed, 95% CI)

2.91 [0.63, 13.32]

3.2 U‐type versus H‐type TVT‐Secur

3

496

Risk Ratio (M‐H, Fixed, 95% CI)

0.77 [0.56, 1.07]

4 Condition‐specific health measures Show forest plot

3

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

4.1 MiniArc versus AJUST

1

60

Mean Difference (IV, Fixed, 95% CI)

‐0.13 [‐1.58, 1.32]

4.2 U‐type versus H‐type TVT‐Secur

2

414

Mean Difference (IV, Fixed, 95% CI)

‐0.30 [‐2.15, 1.55]

5 Duration of operation (minutes) Show forest plot

2

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

5.1 TVT‐Secur versus MiniArc

2

190

Mean Difference (IV, Fixed, 95% CI)

1.70 [‐4.11, 7.51]

5.2 Ajust versus MiniArc

1

80

Mean Difference (IV, Fixed, 95% CI)

1.20 [‐4.67, 7.07]

6 Operative blood loss Show forest plot

3

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

6.1 U‐type versus H‐type TVT‐Secur

2

459

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

6.2 Ajust versus MiniArc

1

80

Mean Difference (IV, Fixed, 95% CI)

‐1.20 [‐10.04, 7.64]

6.3 TVT‐Secur versus MiniArc

1

80

Mean Difference (IV, Fixed, 95% CI)

4.30 [‐5.53, 14.13]

7 Major vascular or visceral injury Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

7.1 U‐type versus H‐type TVT‐Secur

2

459

Risk Ratio (M‐H, Fixed, 95% CI)

0.25 [0.03, 2.19]

8 Bladder or urethral perforation Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

8.1 U‐type versus H‐type TVT‐Secur

2

459

Risk Ratio (M‐H, Fixed, 95% CI)

0.33 [0.01, 7.91]

8.2 TVT‐Secur versus MiniArc

1

110

Risk Ratio (M‐H, Fixed, 95% CI)

4.18 [0.21, 85.11]

9 Vaginal wall perforation Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

9.1 TVT‐S versus MiniArc

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

9.2 U‐type versus H‐type TVT‐Secur

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

10 Urinary retention and need for catheterisation Show forest plot

4

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

10.1 TVT‐Secur versus MiniArc

3

250

Risk Ratio (M‐H, Fixed, 95% CI)

2.05 [0.47, 8.95]

10.2 U‐type versus H‐type TVT‐Secur

1

330

Risk Ratio (M‐H, Fixed, 95% CI)

0.67 [0.11, 3.94]

10.3 Ajust versus MiniArc

1

80

Risk Ratio (M‐H, Fixed, 95% CI)

5.0 [0.25, 100.97]

11 Vaginal mesh exposure Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

11.1 U‐type versus H‐type TVT‐Secur

2

414

Risk Ratio (M‐H, Fixed, 95% CI)

0.79 [0.22, 2.80]

12 Postoperative pain or discomfort Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

12.1 Ajust versus MiniArc

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

12.2 TVT‐Secur versus MiniArc

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

13 De novo urgency Show forest plot

5

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

13.1 TVT‐Secur versus MiniArc

3

250

Risk Ratio (M‐H, Fixed, 95% CI)

0.69 [0.24, 2.02]

13.2 U‐type versus H‐type TVT‐Secur

2

367

Risk Ratio (M‐H, Fixed, 95% CI)

1.09 [0.53, 2.25]

13.3 Ajust versus MiniArc

1

80

Risk Ratio (M‐H, Fixed, 95% CI)

1.5 [0.26, 8.50]

14 Repeat stress incontinence surgery Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

14.1 U‐type versus H‐type TVT‐Secur

2

414

Risk Ratio (M‐H, Fixed, 95% CI)

1.16 [0.54, 2.51]

15 Need for any other additional or new surgical procedure to treat complications Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

15.1 U‐type versus H‐type TVT‐Secur

2

414

Risk Ratio (M‐H, Fixed, 95% CI)

0.27 [0.04, 1.61]

15.2 TVT‐Secur vs Mini‐Arc

1

110

Risk Ratio (M‐H, Fixed, 95% CI)

1.67 [0.16, 17.85]