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Cochrane Database of Systematic Reviews

تک درمانی متوتروکسات در برابر درمان ترکیبی متوتروکسات و داروهای ضدروماتیسمی غیربیولوژیک تعدیل‌کننده بیماری در مدیریت بالینی آرتریت روماتوئید

Información

DOI:
https://doi.org/10.1002/14651858.CD008495Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 14 abril 2010see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Salud musculoesquelética

Copyright:
  1. Copyright © 2015 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Contraer

Autores

  • Wanruchada Katchamart

    Correspondencia a: Rheumatology Division, Department of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

    [email protected]

  • Judith Trudeau

    Department of Rheumatology, CHAUQ‐Hôtel‐Dieu de Lévis, Lévis, Canada

  • Veerapong Phumethum

    Medicine, Prapokklao Hospital, Muang district, Thailand

  • Claire Bombardier

    Institute for Work & Health, Toronto, Canada

Contributions of authors

WK drafted the protocol, CB provided comments

Review of abstracts:‐ WK, JT, and VP

Data abstraction :‐ WK, VP

Assessment of study quality:‐ WK, VP

Review draft :‐ WK, CB

Draft revision and update:‐ WK, CB

Sources of support

Internal sources

  • No sources of support supplied

External sources

  • Abbott international, USA.

    Unrestricted educational grant

Declarations of interest

None at present.

The original article published in the Annals for Rheumatic Diseases was supported by Abbott with an unrestricted educational grant. Abbott had no role in the study design, literature search, data collection, data analysis, data interpretation or writing of the report.

This current review was updated without the support of any industry sponsor.

Acknowledgements

The authors would like to thank Dr. Valalak Srinonprasert, Prof. Maxime Dougados, Prof. Loreta Carmona, Prof. Desiree van der Heijde, Prof. Maarten Boers, Asst. Prof. Vivian Bykerk, Dr. Carine Salliot, Dr. Karen Visser, Dr. Estebaliz Loza, Dr. Juan‐Antonio Martinez, and 3‐e scientific committee for their suggestions and Amy Faulkner for literature search. As well, we would like to thank Dr. Karine Toupin‐April for her assistance with the Summary of Findings table.

Version history

Published

Title

Stage

Authors

Version

2010 Apr 14

Methotrexate monotherapy versus methotrexate combination therapy with non‐biologic disease modifying anti‐rheumatic drugs for rheumatoid arthritis

Review

Wanruchada Katchamart, Judith Trudeau, Veerapong Phumethum, Claire Bombardier

https://doi.org/10.1002/14651858.CD008495

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.