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Cochrane Database of Systematic Reviews

Quimiorradiación preoperatoria para el cáncer rectal localmente avanzado no metastásico

Información

DOI:
https://doi.org/10.1002/14651858.CD008368.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 12 diciembre 2012see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:

  1. Grupo Cochrane de Colorrectal

Copyright:
  1. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Contraer

Autores

  • Kathryn McCarthy

    Correspondencia a: Frenchay Hospital, Bristol, UK

    [email protected]

  • Katherine Pearson

    Dorset County Hospital, Dorchester, UK

  • Rachel Fulton

    University of Glasgow, Glasgow, UK

  • Jonathan Hewitt

    3rd Floor, Academic Building, Llandough Hospital., Cardiff University and Aneurin Bevan Health Board, Cardiff, UK

Contributions of authors

Drafted protocol ‐ KM and JH

Developed search strategy ‐ KP, KM and JH

Searched for trials ‐ KP, KM and JH

Trials selection for inclusion ‐ KM and JH

Data extraction ‐ JH and KM

Data into RevMan analyses ‐ JH

Interpretation of analyses ‐ KM, RF and JH.

Sources of support

Internal sources

  • Portsmouth NHS Trust, UK.

External sources

  • None, Not specified.

Declarations of interest

None declared.

Acknowledgements

Many thanks to Professors Krzysztof Bujko and Sam Ngan for providing additional valuable information. Dr Andrew Bates has provided oncological advice and comment.

Version history

Published

Title

Stage

Authors

Version

2012 Dec 12

Pre‐operative chemoradiation for non‐metastatic locally advanced rectal cancer

Review

Kathryn McCarthy, Katherine Pearson, Rachel Fulton, Jonathan Hewitt

https://doi.org/10.1002/14651858.CD008368.pub2

2010 Feb 17

Neoadjuvant chemoradiation for non‐metastatic locally advanced rectal cancer

Protocol

Jonathan Hewitt, Kathryn McCarthy

https://doi.org/10.1002/14651858.CD008368

Differences between protocol and review

Despite thorough searches we could not find sufficient data to provide information regarding several of the secondary end points of this review which were stated in the protocol. For this reason we did not consider anastomotic leak rate, distant metastases, quality of life and cost of treatment. Hence this review can not comment on these factors.

We amended the original title from 'neoadjuvant chemoradiation' to 'pre‐operative chemoradiation' as we felt this was misleading. Neoadjuvant treatment is usually considered to be primary cancer treatment, however, in the treatment of rectal cancers, it is surgery that is the primary treatment.