Intervenciones farmacológicas para la lesión por isquemia de reperfusión en la cirugía de resección hepática realizada bajo control vascular
Información
- DOI:
- https://doi.org/10.1002/14651858.CD008154Copiar DOI
- Base de datos:
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- Cochrane Database of Systematic Reviews
- Versión publicada:
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- 07 octubre 2009see what's new
- Tipo:
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- Intervention
- Etapa:
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- Review
- Grupo Editorial Cochrane:
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Grupo Cochrane de Hepatobiliar
- Copyright:
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- Copyright © 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Cifras del artículo
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Autores
Contributions of authors
M Abu‐Amara wrote the review after identifying the trials, extracting data, and performing the statistical analysis. K Gurusamy independently identified trials, extracted data from the trials, and helped in the preparation of the manuscript. G Glantzounis, B Fuller, and BR Davidson critically commented on the review and made suggestions to improve the review.
Sources of support
Internal sources
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none, Not specified.
External sources
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none, Not specified.
Declarations of interest
None.
Acknowledgements
Yiping Wang for translation of the Chinese article. The CHBG for their assistance in the preparation of this review.
Peer Reviewers: Jesus Prieto, Spain; Vijay P Khatri, USA.
Contact Editor: Christian Gluud, Denmark.
Version history
| Published | Title | Stage | Authors | Version |
| 2009 Oct 07 | Pharmacological interventions for ischaemia reperfusion injury in liver resection surgery performed under vascular control | Review | Mahmoud Abu‐Amara, Kurinchi Selvan Gurusamy, George Glantzounis, Barry Fuller, Brian R Davidson | |
Differences between protocol and review
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In the Background section, the number of examples of pharmacological agents that were discussed in the protocol have been reduced, and those that remained have been placed under the appropriate comparison in the discussion. This was done to improve the readability and consistency of the review as too many examples were included in the protocol.
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In the Types of interventions section of the methods, only pharmacological interventions versus other pharmacological interventions were included in the review. Pharmacological interventions versus no pharmacological interventions are assessed in a separate review (Abu‐Amara 2009). This was done to reduce the length and improve the readability of the review based on the recommendations of CHBG Editors.
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The outcomes were reordered to give more importance to clinically relevant outcomes.
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The 'Risk of bias' assessment has been modified in line with The CHBG module (Gluud 2009; Gurusamy 2009d).
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In the protocol we stated that we would calculate the risk ratio with 95% confidence intervals for dichotomous outcomes. However, there was only one trial included under each comparison and this is why we performed Fisher's exact test for the dichotomous outcomes.
Notes
The original protocol for this review encompassed all randomised trials that assessed one or more pharmacological interventions versus another pharmacological intervention or no pharmacological intervention (REF to the Protocol!). In order to reduce the length and improve the readability of the full review emanating from the protocol, two separate reviews are being published instead of one.
This review only evaluates pharmacological interventions versus other pharmacological interventions. The other review (Abu‐Amara 2009) evaluates only trials comparing pharmacological interventions versus no pharmacological intervention (placebo or control). These changes are based on the recommendations of CHBG Editors.
