| Ang 2000 | Number of participants: I: 17; C: 22. % TBSA burned (Mean; SE; Range): I: 2.16; 0.38; 0.13‐6.0:
C: 1.56; 0.18; 0.5‐3.5. | Initial number of participants: 115. After randomisation: I: 57; C: 58. Drop‐outs:I: 3; C: 0. Participants with facial burns: I: 17; C:22. Particpants in short term analysis: I: 17; C: 22. Participants in long term analysis: I:17; C: 20. | Number of days taken for face‐wound to heal: I: 2‐35 days (range); C: not reported. Proportion completely healed in 10 days: I: 14/17; C: 17/22. | Need for reconstructive surgery 6 months PB: I: 0/17; C: 0/20. |
| Demling 1999 | Number of participants: Minor burns: I: 5; C: 5.
Major burns: I: 5; C: 6. Mean age (SD years): Minor burns: I: 31(8); C: 29(7).
Major burns: I: 44(10); C: 40(8). Etiology: Flame. % TBSA burned (Mean (SD)): Minor burns: I: 10(3); C: 7(2).
Major burns: I: 32(9); C: 30(8). % TBSA burned Full‐thickness (Mean (SD)): Minor burns: I: 0; C:0.
Major burns: I: 10(3); C: 8(2). | Initial number of participants: 21. Number of participants with minor burns: 10. Number of participants with major burns: 11. After randomisation: Minor burns: I: 5; C: 5.
Major burns: I: 5; C: 6. Participants in short term analysis: Minor burns: I: 5; C: 5.
Major burns: I: 5; C: 6. | Mean number of days to > 90% re‐epithelialisation (SD): Minor burns:
I: 8(1); C: 12(3); significantly different P < 0.05. Major burns:
I: 8(2); C: 14(4); significantly different P < 0.05. Signs of local wound infection: Minor burns: I: 0; C: 0.
Major burns: I: 0; C: 0. | Pain during facial care (Mean (SD)): Minor burns: I: 2(1); C: 5(1).
Major burns: I: 2(1); C: 5(1). Pain between facial care (Mean (SD)): Minor burns: I: 1(0.5); C: 3(2).
Major burns: I: 2(1); C: 4(2). Mean length of stay (SD): Minor burns: I: 1(0.5); C: 3(1).
Major burns: Not reported. |
| Demling 2002 | Number of participants:I: 16; C: 18. Mean age (SD):I: 39(9); C: 40(8). Etiology: Flame: I: 11; C: 12.
Scald: I: 5; C: 6. % TBSA burned (Mean (SD)): I: 24(8); C: 21(9). % TBSA burned Full‐thickness (Mean (SD)):
I: 12(7); C: 10(6). | Initial number of participants: 34. After randomisation: I: 16; C: 18. Participants in short term analysis: I: 16; C: 18. | Mean number of days to > 95% re‐epithelialisation (SD): I: 9(4); C: 15(4); significantly different P < 0.05. Signs of infection diagnosed with swab cultures exceeding 105 organisms/gram: I: 0; C: 0. | Pain during facial care (Mean (SD)): I: 3(1); C: 7(2). Pain between facial care (Mean (SD)): I: 2(1); C: 4(2). |
| Desai 1991 | Number of participants: I: 7; C: 8. Mean age (SE):I: 11.4 (1.2); C: 9.5(1.6). % TBSA burned (Mean (SE)): I: 35(7); C: 50(6). % TBSA burned Full‐thickness (Mean (SE)):I: 20(9); C: 32(7). | Initial number of participants: 15. After randomisation: I: 7; C: 8. Participants in short term analysis: I: 7; C: 8. | Cases of wound infection diagnosed with the occurrence of chondritis: I: 3; C: 4. | Mean number (SE) of surgical procedures required: I: 1.2(0.1) C: 1.0(0); significantly different P < 0.05. Adverse effect of treatment: occurrence of gentamicin‐resistant micro‐organisms I: 29%; C: 0%. Mean length of stay (SE): I: 26(1); C: 38(3). |
| Horch 2005 | Number of participants: I: 5; C: 5. Median age (range): I + C: 34.3(24‐67). | Initial number of participants: 10. After randomisation: I: 5; C: 5. Participants in short term analysis: I: 5; C: 5. | Median number of days to complete re‐epithelialisation:
I:10.5; C: 12.4; significantly different P < 0.05. Signs of underlying infection: I: 0; C: not reported | Hypertrophic scar formation: I: 0; C: 2. Adverse effect of treatment: localized partial integration of the biological dressing I: 1; C: 0. |
