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Cochrane Database of Systematic Reviews

Linezolid versus vancomicina para las infecciones de piel y partes blandas

Información

DOI:
https://doi.org/10.1002/14651858.CD008056.pub3Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 07 enero 2016see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Heridas

Copyright:
  1. Copyright © 2016 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Autores

  • Jirong Yue

    Center of Geriatrics and Gerontology, West China Hospital, Sichuan University, Chengdu, China

  • Bi Rong Dong

    Correspondencia a: Center of Geriatrics and Gerontology, West China Hospital, Sichuan University, Chengdu, China

    [email protected]

  • Ming Yang

    Center of Geriatrics and Gerontology, West China Hospital, Sichuan University, Chengdu, China

  • Xiaomei Chen

    Department of Dermatology & Venereology, West China Hospital, Sichuan University, Chengdu, China

  • Taixiang Wu

    Chinese Clinical Trial Registry, Chinese Ethics Committee of Registering Clinical Trials, West China Hospital, Sichuan University, Chengdu, China

  • Guan J Liu

    Chinese Cochrane Centre, Chinese Evidence‐Based Medicine Centre, West China Hospital, Sichuan University, Chengdu, China

Contributions of authors

Yue Jirong: conceived the review question; co‐ordinated the protocol development; completed the first draft and edited the review.
Dong Birong: developed the review and advised on the review, co‐ordinated the review development and performed part of writing and editing of the review, approved the final version of the review prior to submission and is guarantor.
Yang Ming: developed and edited the review and made an intellectual contribution to it.
Chen Xiaomei: conceived the review question, edited the review and made an intellectual contribution to it.
Wu Taixiang: developed the review, advised and performed part of writing and editing of the review, and made an methodological contribution.
Liu Guanjian: advised and performed part of writing and editing of the review, and made a statistical contribution.

Contributions of editorial base

Nicky Cullum: edited the review; advised on methodology, interpretation and review content.
Julie Bruce, Editor: approved the final review prior to submission.
Sally Bell‐Syer: co‐ordinated the editorial process. Advised on methodology, interpretation and content. Edited and copy edited the review.
Ruth Foxlee: designed the search strategy and edited the search methods section.

Sources of support

Internal sources

  • Chinese Cochrane Center, China.

External sources

  • This project was supported by the National Institute for Health Research via Cochrane Infrastructure funding to Cochrane Wounds. The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the Systematic Reviews Programme, NIHR, NHS or the Department of Health, UK.

Declarations of interest

Yue Jirong: none known.
Dong Birong: none known.
Yang Ming: none known.
Chen Xiaomei: none known.
Wu Taixiang: none known.
Liu Guanjian: none known.

Acknowledgements

We would like to thank the following peer referees for their helpful comments on the review: Julie Bruce, Susan O’Meara, Ruth Foxlee, Jane Burch, Elmer Villanueva, Beryl de Souza, Brian Gilchrist, Patricia Davies, Shirley Manknell. Sally Bell‐Syer is especially acknowledged for language assistance, and Nicola Thomis for her contributions to the glossary. We also would like to acknowledge the copy editor, Elizabeth Royle, for edits to our draft.

Version history

Published

Title

Stage

Authors

Version

2016 Jan 07

Linezolid versus vancomycin for skin and soft tissue infections

Review

Jirong Yue, Bi Rong Dong, Ming Yang, Xiaomei Chen, Taixiang Wu, Guan J Liu

https://doi.org/10.1002/14651858.CD008056.pub3

2013 Jul 12

Linezolid versus vancomycin for skin and soft tissue infections

Review

Jirong Yue, Bi Rong Dong, Ming Yang, Xiaomei Chen, Taixiang Wu, Guan J Liu

https://doi.org/10.1002/14651858.CD008056.pub2

2009 Oct 07

Linezolid versus vancomycin for skin and soft tissue infections

Protocol

Jirong Yue, Bi Rong Dong, Ming Yang, Xiaomei Chen, Taixiang Wu, Guan J Liu

https://doi.org/10.1002/14651858.CD008056

Differences between protocol and review

  1. Under "Types of outcome measures/Primary outcomes" in the sentence "Proportion of patients or infections healed: healing is defined as either the resolution of all clinical signs and symptoms of infection, as assessed by laboratory test or as defined by trialists", we changed to, "clinical cure (resolution of symptoms and signs) and microbiological cure (eradication of bacteria on wound culture)." We think the meaning of the two statements is the same, however, "clinical/microbiological cure" is more concise and helpful than the original wording when used throughout the text of the review.

  2. In the section "Subgroup analysis and investigation of heterogeneity", we added:"3. MRSA subset", because MRSA is important for SSTIs. The morbidity and treatment costs associated with MRSA‐infected SSTIs are higher than for other pathogen infections, so we added this subgroup analysis.

  3. We added some information in the "Background" section in line with comments from peer referees.

  4. We added some information in the "Methods/Dealing with missing data" section, in line with comments from peer referees.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.