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Cochrane Database of Systematic Reviews

Suplementos de zinc para el desarrollo mental y motor en niños

Información

DOI:
https://doi.org/10.1002/14651858.CD007991.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 12 diciembre 2012see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Problemas de desarrollo, psicosociales y de aprendizaje

Copyright:
  1. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Autores

  • Siddhartha Gogia

    Correspondencia a: Department of Pediatrics and Neonatology, Max Hospital, Gurgaon, India

    [email protected]

  • Harshpal S Sachdev

    Department of Pediatrics and Clinical Epidemiology, Sitaram Bhartia Institute of Science and Research, New Delhi, India

Contributions of authors

SG and HPS wrote the protocol. Both authors extracted data independently. Both authors analyzed data and drafted the final paper.

Sources of support

Internal sources

  • Sitaram Bhartia Institute of Science and Research, India.

  • Max Hospital, Gurgaon, Haryana, India.

External sources

  • Effective Health Care Research Consortium, UK.

Declarations of interest

Siddhartha Gogia ‐ received a consultancy fee from EHCRC/Cochrane Infectious Diseases Group, International Health Group, Liverpool School of Tropical Medicine, Liverpool, UK through The Institute of Child Care Research, Queen's University, Belfast, Northern Ireland to support loss of earnings while working on this Cochrane review.
Harshpal S Sachdev ‐ is an editor in the Cochrane Developmental, Psychosocial and Learning Problems Group.

Acknowledgements

The authors acknowledge the support provided by the Effective Health Care Research Consortium (EHCRC)/Cochrane Infectious Diseases Group, International Health Group, Liverpool School of Tropical Medicine, Liverpool, UK through The Institute of Child Care Research, Queen's University, Belfast, Northern Ireland.

Version history

Published

Title

Stage

Authors

Version

2012 Dec 12

Zinc supplementation for mental and motor development in children

Review

Siddhartha Gogia, Harshpal S Sachdev

https://doi.org/10.1002/14651858.CD007991.pub2

2009 Jul 08

Zinc supplementation for mental and motor development in children

Protocol

Siddhartha Gogia, Harshpal S Sachdev

https://doi.org/10.1002/14651858.CD007991

Differences between protocol and review

We anticipated that studies would use different developmental scales for evaluating the effect of zinc supplementation on mental and motor development in children. Hence, during the protocol stage, we had planned to combine the data derived from studies using BSID (usually reported as MDI and PDI) into a single composite measure for ease of combination with studies using developmental scales providing a single composite measure of development (for example, Griffiths Mental Developmental Scale). However, after applying the search strategy, eight studies had reported data using BSID and only one study reported data in Griffiths Mental Developmental Scale. It presented an excellent opportunity to report effects on both MDI and PDI separately (given the absolute number and marked preponderance of studies using BSID), so as to delineate the exact developmental domains affected by zinc supplementation further. Hence we decided to include the eight studies reporting data using BSID in the meta‐analysis and to use MDI and PDI, so as to provide the exact benefit of zinc supplementation in terms of BSID units. The study using the Griffiths Mental Developmental Scale (Gardner 2005) has been reported in detail in the text and the Characteristics of included studies table.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.