Appendix 1. MEDLINE via OVID search strategy

1. exp Ankylosis/

2. (ankylos$ or ancylos$).mp.

3. 1 or 2

4. Tooth fractures/

5. Tooth injuries/

6. Tooth avulsion/

7. (tooth and (injur$ or fractur$ or traum$ or avuls$ or dislodg$ or sublux$ or "knocked out")).mp.

8. (teeth and (injur$ or fractur$ or traum$ or avuls$ or dislodg$ or sublux$ or "knocked out")).mp.

9. or/4‐8

10. 3 and 9

The above subject search was linked to the Cochrane Highly Sensitive Search Strategy (CHSSS) for identifying randomized trials in MEDLINE: sensitivity maximising version (2008 revision) as referenced in Chapter 6.4.11.1 and detailed in box 6.4.c of The Cochrane Handbook for Systematic Reviews of Interventions, Version 5.1.0 [updated March 2011](Higgins 2011).

1. randomized controlled trial.pt.
2. controlled clinical trial.pt.
3. randomized.ab.
4. placebo.ab.
5. drug therapy.fs.
6. randomly.ab.
7. trial.ab.
8. groups.ab.
9. or/1‐8
10. exp animals/ not humans.sh.
11. 9 not 10

Appendix 2. Cochrane Oral Health Group Trials Register search strategy

From April 2014, searches were undertaken using the Cochrane Register of Studies and the search strategy below:

((ankylos* or ancylos*) AND (tooth or teeth)):ti,ab

Previous searches were undertaken in September 2009 and April 2012 using the Procite software and the search strategy below:

((ankylos* or ancylos*) and ((tooth or teeth) and (injur* or fract* or trauma* or avuls* or sublux* or dislodg* or "knocked out")))

Appendix 3. CENTRAL search strategy

#1 MeSH descriptor Ankylosis explode all trees
#2 (ankylos* in All Text or ancylos* in All Text)
#3 (#1 or #2)
#4 MeSH descriptor Tooth fractures explode all trees
#5 MeSH descriptor Tooth injuries this term only
#6 MeSH descriptor Tooth avulsion this term only
#7 (tooth in All Text and (injur* in All Text or fractur* in All Text or traum* in All Text or avuls* in All Text or dislodg* in All Text or sublux* in All Text or "knocked out" in All Text) )
#8 (teeth in All Text and (injur* in All Text or fractur* in All Text or traum* in All Text or avuls* in All Text or dislodg* in All Text or sublux* in All Text or "knocked out" in All Text) )
#9 (#4 or #5 or #6 or #7 or #8)
#10 (#3 and #9)

Appendix 4. EMBASE via OVID search strategy

1. exp Ankylosis/

2. (ankylos$ or ancylos$).mp.

3. 1 or 2

4. Tooth fractures/

5. Tooth injuries/

6. Tooth avulsion/

7. (tooth and (injur$ or fractur$ or traum$ or avuls$ or dislodg$ or sublux$ or "knocked out")).mp.

8. (teeth and (injur$ or fractur$ or traum$ or avuls$ or dislodg$ or sublux$ or "knocked out")).mp.

9. or/4‐8

10. 3 and 9

Appendix 5. LILACS search strategy

(ankylos$ or ancylos$ or anquilo$ or ancilos$)

AND

((tooth or teeth or dent$) AND (fract$ or injur$ or lesoes or lesion$ or fratur$ or trauma or avuls$ or dislodg$ or deslocam$ or desaloja$ or sublux$ or "knocked out"))

Appendix 6. US National Institutes of Health (ClinicalTrials.gov) Search Strategy

ankylosis or ankylosed or ankylose
ancylosis or ancylosed or ancylose

Appendix 7. WHO International Clinical Trials Registry Platform Search Strategy

ankylosis AND teeth OR ankylosed AND teeth OR ankylose AND teeth