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Intervenções não cirúrgicas para hordéolos internos agudos

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Referencias

References to studies excluded from this review

Bahgat 1986 {published data only}

Bahgat MM. Comparative study of local injection therapy of chalazia. Orbit 1986;5(3):219‐22. CENTRAL

Chen 2000 {published data only}

Chen H. Effective observation on 111 cases of hordeolum treated by bloodleting in the point of ear. Journal of Guiyang College of Traditional Chinese Medicine 2000;22(1):29. CENTRAL

Comstock 2012 {published and unpublished data}

Comstock TL, Paterno MR, Bateman KM, Decory HH, Gearinger M. Safety and tolerability of loteprednol etabonate 0.5% and tobramycin 0.3% ophthalmic suspension in pediatric subjects. Paediatric Drugs 2012;14(2):119‐30. CENTRAL

Copeman 1958 {published data only}

Copeman PW. Treatment of recurrent styes. Lancet 1958;2(7049):728‐9. CENTRAL

Gao 2001 {published data only}

Gao Q. Treatment of hordeolum by wrist‐ankle acupuncture. Shanghai Journal of Acupuncture and Moxibustion 2001;20(5):19. CENTRAL

Garrett 1988 {published data only}

Garrett GW, Gillespie ME, Mannix BC. Adrenocorticosteroid injection vs. conservative therapy in the treatment of chalazia. Annals of Ophthalmology 1988;20(5):196‐8. CENTRAL

Gordon 1970 {published data only}

Gordon DM. Gentamicin sulfate in external eye infections. American Journal of Ophthalmology 1970;69(2):300‐6. CENTRAL

Hatano 1969 {published data only}

Hatano H, Saito T, Takahashi N. Ophthalmological application of minocycline. Japanese Journal of Antibiotics 1969;22(6):522‐5. CENTRAL

Hatano 1974 {published data only}

Hatano H, Tokuda H, Kayaba C. Evaluation of amikacin (BB‐K8) in ophthalmological field. Japanese Journal of Antibiotics 1974;27(4):451‐5. CENTRAL

Hirunwiwatkul 2005 {published and unpublished data}

Hirunwiwatkul P, Wachirasereechai K. Effectiveness of combined antibiotic ophthalmic solution in the treatment of hordeolum after incision and curettage: a randomized, placebo‐controlled trial: a pilot study. Journal of the Medical Association of Thailand 2005;88(5):647‐50. CENTRAL

Jacobs 1984 {published data only}

Jacobs PM, Thaller VT, Wong D. Intralesional corticosteroid therapy of chalazia: a comparison with incision and curettage. British Journal of Ophthalmology 1984;68(11):836‐7. CENTRAL

Kastl 1987 {published data only}

Kastl PR, Ali Z, Mather F. Placebo‐controlled, double‐blind evaluation of the efficacy and safety of yellow mercuric oxide in suppression of eyelid infections. Annals of Ophthalmology 1987;19(10):376‐9. CENTRAL

Laibson 1981 {published data only}

Laibson P, Michaud R, Smolin G, Okumoto M, Rosenthal A, Cagle G. A clinical comparison of tobramycin and gentamicin sulfate in the treatment of ocular infections. American Journal of Ophthalmology 1981;92(6):836‐41. CENTRAL

Magnuson 1967 {published data only}

Magnuson RH, Suie T. Gentamicin sulfate in external eye infections. JAMA 1967;199(6):427‐8. CENTRAL

Manabe 1981 {published data only}

Manabe R, Moriyama H, Suda T. A double‐blind study of tobramycin eye drops on infectious diseases of anterior portion of the eye. Comparison with gentamicin eye drops. Folia Ophthalmologica Japonica 1981;32(4):1041‐65. CENTRAL

Mathew 1966 {published data only}

Mathew M. Munomycin in hordeolum externum. Indian Practitioner 1966;19(10):689‐90. CENTRAL

NCT01763437 {published data only}

NCT01763437. Intralesional tetracycline injection in the treatment of chalazia (TET). clinicaltrials.gov/ct2/show/NCT01763437 (accessed 9 December 2016). CENTRAL

NCT02338648 {published data only}

NCT02338648. Safety and efficacy study of SUN 131 TDS as compared to placebo TDS in adult patients with a chalazion. clinicaltrials.gov/ct2/show/NCT02338648 (accessed 9 December 2016). CENTRAL

Oishi 1973 {published data only}

Oishi M, Imai M, Takahashi T, Motoyama M, Tanaka M. Clinical evaluation of clindamycin‐2‐palmitate for ophthalmic infections of children. Japanese Journal of Antibiotics 1973;26(6):535‐9. CENTRAL

Panda 1987 {published data only}

Panda A, Angra SK. Intralesional corticosteroid therapy of chalazia. Indian Journal of Ophthalmology 1987;35(4):183‐5. CENTRAL

Sawae 1971 {published data only}

Sawae Y, Inoue H, Shiraishi M, Fujimura T, Takemori K. Laboratory and clinical evaluation of clindamycin. Japanese Journal of Antibiotics 1971;24(2):51‐8. CENTRAL

Takama 2006 {published data only}

Takama N, Fujiwara T. The efficacy of hainou‐san‐kyu‐to for internal hordeolum. Ganka Rinsho Iho (Japanese Review of Clinical Ophthalmology) 2006;100:9‐11. CENTRAL

Vácha 1987 {published data only}

Vácha J, Bodnár M. Kenalog injection-one possibility in the treatment of chronic chalazion. Ceskoslovenska Oftalmologie 1987;43(5):374‐6. CENTRAL

Wang 1983 {published data only}

Wang TM. Treatment of tarsal cyst by local injection of cortisone. Zhonghua Yan Ke Za Zhi (Chinese Journal of Ophthalmology) 1983;19(3):168‐9. CENTRAL

Watson 1984 {published data only}

Watson AP, Austin DJ. Treatment of chalazions with injection of a steroid suspension. British Journal of Ophthalmology 1984;68(11):833‐5. CENTRAL

Willcox 2008 {published data only}

Willcox M, Bengaly T, Lopez V, Falquet J, Lambert B, Diallo D. Traditional malian ointment for styes. Journal of Alternative and Complementary Medicine 2008;14(5):461‐4. CENTRAL

Xu 2004 {published data only}

Xu W. Clinical observation on 67 cases of hordeolum treated by acupuncture and blood letting on ear. Hunan Guiding Journal of Traditional Chinese Medicine 2004;10(5):47. CENTRAL

Additional references

Avisar 1991

Avisar R, Savir H, Deutsch D, Teller J. Effect of I‐Scrub on signs and symptoms of chronic blepharitis. DICP: the Annals of Pharmacotherapy 1991;25(4):359‐60.

Barza 1983

Barza M, Baum J. Ocular infections. Medical Clinics of North America 1983;67(1):131‐52.

Cheng 2014

Cheng K, Wang X, Guo M, Wieland LS, Shen X, Lao L. Acupuncture for acute hordeolum. Cochrane Database of Systematic Reviews 2014, Issue 4. [DOI: 10.1002/14651858.CD011075]

De Jesus 2004

De Jesus JM. Treating hordeola with systemic medications: first‐line therapy with oral antibiotics for the treatment of hordeola may provide a more permanent resolution. Pacific Optometry. www.opt.pacificu.edu/test/journal/Articles/deJesus%20hordeola/hordeola.html (accessed 4 June 2008).

Deeks 2011

Deeks JJ, Higgins JP, Altman DG editor(s). Chapter 9: Analysing data and undertaking meta‐analyses. In: Higgins JP, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from handbook.cochrane.org.

Diegel 1986

Diegel JT. Eyelid problems. Blepharitis, hordeola, and chalazia. Postgraduate Medicine 1986;80(2):271‐2.

Driver 1996

Driver PJ, Lemp MA. Meibomian gland dysfunction. Survey of Ophthalmology 1996;40(5):343‐67.

Fraunfelder 1971

Fraunfelder FT, Roy FH. How to treat common external eye problems. American Family Physician 1971;3(4):104‐9.

Fuchs 1911

Fuchs E. Textbook of Ophthalmology. JB Lippincott Company, 1911.

Glanville 2006

Glanville JM, Lefebvre C, Miles JN, Camosso‐Stefinovic J. How to identify randomized controlled trials in MEDLINE: ten years on. Journal of the Medical Library Association 2006;94(2):130‐6.

Higgins 2011

Higgins JP, Altman DG, Sterne JAC editor(s). Chapter 8: Assessing risk of bias in included studies. In: Higgins JP, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from handbook.cochrane.org.

Hudson 1981

Hudson RL. Treatment of styes and meibomian cysts. Practical procedures. Australian Family Physician 1981;10(9):714‐5.

King 1986

King RA, Ellis PP. Treatment of chalazia with corticosteroid injections. Ophthalmic Surgery 1986;17(6):351‐3.

Lebensohn 1950

Lebensohn JE. Treatment of hordeola. Postgraduate Medicine 1950;7(2):133.

Lederman 1999

Lederman C, Miller M. Hordeola and chalazia. Pediatrics in Review 1999;20(8):283‐4.

McCulley 1984

McCulley JP. Blepharoconjunctivitis. International Ophthalmology Clinics 1984;24(2):65‐77.

Moriarty 1982

Moriarty PA, Collin JR. Eyelid problems. Practitioner 1982;226(1367):901‐23.

Mueller 2008

Mueller JB, McStay CM. Ocular infection and inflammation. Emergency Medicine Clinics of North America 2008;26(1):57‐72.

Olson 1991

Olson MD. The common stye. Journal of School Health 1991;61(2):95‐7.

Palva 1983

Palva J, Pohjanpelto PEJ. Intralesional corticosteroid injection for the treatment of chalazia. Acta Ophthalmologica 1983;61(5):933‐7.

Panicharoen 2011

Panicharoen C, Hirunwiwatkul P. Current pattern treatment of hordeolum by ophthalmologists in Thailand. Journal of the Medical Association of Thailand 2011;94(6):721‐4.

Peralejo 2008

Peralejo B, Beltrani V, Bielory L. Dermatologic and allergic conditions of the eyelid. Immunology and Allergy Clinics of North America 2008;28(1):137‐68.

RevMan 2014 [Computer program]

Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.3. Copenhagen: Nordic Cochrane Centre, The Cochrane Collaboration, 2014.

Roodyn 1954

Roodyn L. Staphylococcal infections in general practice. British Medical Journal 1954;2(4900):1322‐5.

Rubin 1995

Rubin S, Hallagan L. Lids, lacrimals, and lashes. Emergency Medicine Clinics of North America 1995;13(3):631‐48.

Scobee 1942

Scobee RG. The role of the meibomian glands in recurrent conjunctivitis. American Journal of Ophthalmology 1942;25:184‐92.

Sethuraman 2009

Sethuraman U, Kamat D. The red eye: evaluation and management. Clinical Pediatrics 2009;48(6):588‐600.

Skorin 2002

Skorin L. Hordeolum and chalazion treatment: the full gamut. Optometry Today2002, issue June 28:25‐7.

Wald 2004

Wald ER. Periorbital and orbital infections. Infectious Disease Clinics of North America 2004;25(9):312‐20.

Wilkie 1956

Wilkie JL. Styes. Practitioner 1956;176(1053):318‐21.

References to other published versions of this review

Lindsley 2010

Lindsley K, Nichols JJ, Dickersin K. Interventions for acute internal hordeolum. Cochrane Database of Systematic Reviews 2010, Issue 9. [DOI: 10.1002/14651858.CD007742.pub2]

Lindsley 2013

Lindsley K, Nichols JJ, Dickersin K. Interventions for acute internal hordeolum. Cochrane Database of Systematic Reviews 2013, Issue 4. [DOI: 10.1002/14651858.CD007742.pub3]

Characteristics of studies

Characteristics of excluded studies [ordered by study ID]

Study

Reason for exclusion

Bahgat 1986

Population not eligible: CCT of participants with chalazia, defined as chronic lipogranulomas with duration of one month to three years before therapy. Participants were stratified by type of chalazia and were assigned to injections of corticosteroids with or without antibiotics, or to control.

Chen 2000

Intervention not eligible: RCT of participants with internal and external hordeolum randomly assigned to bloodletting of the ear or no treatment.

Comstock 2012

Population not eligible: RCT of pediatric participants with lid inflammation to evaluate the safety and efficacy of Zylet® compared with vehicle. As the focus of the trial was primarily safety of Zylet® in pediatric patients, eligibility criteria were not strict and subgroup data for specific diagnoses were not collected.

Copeman 1958

Population not eligible: CCT of participants with recurrent external hordeola, defined as at least one previous stye of the eyelash follicle within the last month. Patients alternately assigned to antibiotic ointment or control applied to the anterior nares.

Gao 2001

Intervention not eligible: RCT of participants with hordeolum randomly assigned to wrist‐ankle acupuncture or oral ofloxacin plus topical chloramphenicol.

Garrett 1988

Population not eligible: RCT of participants with chalazia, defined as chronic inflammation of the meibomian glands. Participants randomly assigned to warm compresses and lid scrubs, intralesional steroid injections, or both treatments.

Gordon 1970

Population not eligible: RCT of participants with acute, subacute, or chronic external eye infections. Participants randomly assigned to treatment with topical gentamicin or topical combination of neomycin, bacitracin, and polymyxin. Of the 104 participants studied, none were diagnosed with hordeolum.

Hatano 1969

Population not eligible: interventional case series of participants with ophthalmic infection. Of the 28 participants studied, 10 were diagnosed with hordeolum, but internal and external cases were not specified. All participants received topical minocycline.

Hatano 1974

Population not eligible: interventional case series of participants with ophthalmic infection. Of the 40 participants studied, 10 were diagnosed with hordeolum, but internal and external cases were not specified. Four of these participants underwent surgery at the time of first consult, and six received the antibiotic amikacin.

Hirunwiwatkul 2005

Intervention not eligible: RCT of participants with internal and external hordeolum after undergoing surgical incision and curettage. Participants randomly assigned to treatment with antibiotic ophthalmic solution or placebo after surgery.

Jacobs 1984

Population not eligible: RCT of participants with noninfectious chalazia present for two or more weeks. Participants randomly assigned to injection with triamcinolone or incision and curettage.

Kastl 1987

Population not eligible: RCT of participants with active eyelid infection (styes and blepharitis) determined by cultures taken from the base of the eyelashes. Participants randomly assigned to treatment with yellow mercuric oxide or placebo.

Laibson 1981

Population not eligible: RCT of participants with acute ocular infections. Participants randomly assigned to tobramycin ophthalmic solution or gentamicin ophthalmic solution. Of the 68 participants studied, none were diagnosed with hordeolum.

Magnuson 1967

Population not eligible: interventional case series of participants with various eye infections, with most having conjunctivitis, meibomianitis, or blepharitis. Of the 131 participants studied, as many as three may have had a stye. All participants received gentamicin sulfate and hot and cold compresses.

Manabe 1981

Population not eligible: CCT of participants with infection of the anterior portion of the eye. Participants were assigned by order of enrolment to treatment with tobramycin ophthalmic solution or gentamicin ophthalmic solution. Of the 504 participants studied, 43 were diagnosed with hordeolum, but internal and external cases were not specified. Data were not reported separately for hordeolum cases.

Mathew 1966

Population not eligible: interventional case series of participants with external hordeola, defined as acute inflammation of the glands situated at the root of eye lashes. All participants received penicillin and streptomycin plus a polyvalent antigen (Munomycin).

NCT01763437

Population not eligible: RCT of participants with chalazia of longer than one week duration. Participants assigned to injection with tetracycline or observation.

NCT02338648

Population not eligible: RCT of participants with chalazia, defined as visible single granulomas in the upper or lower eyelid. Participants assigned to an investigation transdermal patch or placebo.

Oishi 1973

Not a controlled trial: interventional case series of 26 children with ophthalmic infection, three of whom had internal hordeolum. All participants received topical clindamycin‐2‐palmitate.

Panda 1987

Population not eligible: CCT of participants with chalazia, defined as chronic inflammatory granulomas. Participants assigned to injection with one of three corticosteroids: dexamethasone, hydrocortisone, or triamcinolone.

Sawae 1971

Population not eligible: interventional case series of participants with ophthalmic infection. Of the 22 participants studied, one was diagnosed with hordeolum, but it was not specified as being internal or external. All patients received clindamycin.

Takama 2006

Intervention not eligible: RCT of participants with hordeolum randomly assigned to receive Chinese herbal medicine or no Chinese herbal medicine supplementary to topical ofloxacin and fluorometholone.

Vácha 1987

Population not eligible: observational study of participants with chalazia, defined as granulomas. Treatment with kenalog injections was compared with incision and curettage.

Wang 1983

Population not eligible: CCT of participants with chalazia, defined as tarsal cyst. Participants assigned to local injection of one of two corticosteroids.

Watson 1984

Population not eligible: CCT of participants with chalazia, defined as chronic granulomas. Participants alternately assigned to injection with triamcinolone acetonide or incision and curettage.

Willcox 2008

Population not eligible: case report of a participant treated with malian ointment for a stye.

Xu 2004

Intervention not eligible: RCT of participants with hordeolum randomly assigned to acupuncture plus bloodletting of the ear or sham therapy.

CCT: controlled clinical trial
RCT: randomized clinical trial

Study flow diagram.
Figuras y tablas -
Figure 1

Study flow diagram.