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Cochrane Database of Systematic Reviews

Procalcitonin to initiate or withhold antibiotics in acute respiratory tract infections

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Información

DOI:
https://doi.org/10.1002/14651858.CD007498Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 08 octubre 2008see what's new
Tipo:
  1. Intervention
Etapa:
  1. Protocol
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Infecciones respiratorias agudas

Copyright:
  1. Copyright © 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Autores

  • Philipp Schuetz

    Correspondencia a: Division of Endocrinology, Diabetes and Clinical Nutrition, University Hospital Basel (USB), Basel, Switzerland

    [email protected]

    [email protected]

  • Matthias Briel

    Basel Institute for Clinical Epidemiology, Internal Medicine, University Hospital Basel (USB), Basel, Switzerland

  • Mirjam Christ‐Crain

    Division of Endocrinology, Diabetes and Clinical Nutrition, University Hospital Basel (USB), Basel, Switzerland

  • Marcel Wolbers

    Basel Institute for Clinical Epidemiology, University Hospital Basel (USB), Basel, Switzerland

  • Daiana Stolz

    Clinic of Pneumology and Pulmonary Cell Research, University Hospital Basel (USB), Basel, Switzerland

  • Michael Tamm

    Clinic of Pneumology and Pulmonary Cell Research, University Hospital Basel (USB), Basel, Switzerland

  • Heiner Bucher

    Basel Institute for Clinical Epidemiology, University Hospital Basel (USB), Basel, Switzerland

  • Beat Müller

    Division of Endocrinology, Diabetes and Clinical Nutrition, University Hospital Basel (USB), Basel, Switzerland

Contributions of authors

Philipp Schuetz (PS), Matthias Briel (MB), Mirjam Christ‐Crain (MCC), Daiana Stolz (DS), Heiner C Bucher (HCB), Michael Tamm (MT), and Beat Mueller (BM) are responsible for drafting the initial protocol, updating the text with comments from investigators from other trials, conducting the literature search, evaluating all studies for eligibility, and contacting authors of new trials. In addition, they will be involved in the initial analyses and drafting of the review. Marcel Wolbers (MW) will provide statistical input during all phases of the review.

One investigator from other eligible trials will be identified and invited to participate in the IPD working group and therefore become a co‐author in the final review. They will be responsible for providing the protocol, study report, and complete data set and help address all queries in the data clearing process. They will also provide feedback on the initial protocol, the analyses and the final review. The provided data sets will not be used for any analysis outside of the individual patient meta‐analysis.

Declarations of interest

BM, MCC, PS and DS have served as consultants and received payments from Brahms (the manufacturer of procalcitonin assay used in the studies) to attend meetings related to the trial and for travel expenses, speaking engagements, and research.

Acknowledgements

We thank all participating patients and the staff of the clinics of emergency medicine and internal medicine, and the department of clinical chemistry from all the participating hospitals for most helpful support during the individual studies. We also wish to thank the following people for commenting on the draft protocol: Hayley Edmonds, Anette Holm, Renato Seligman, Richard Shoemaker, and Roger Damoiseaux.

Version history

Published

Title

Stage

Authors

Version

2017 Oct 12

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections

Review

Philipp Schuetz, Yannick Wirz, Ramon Sager, Mirjam Christ‐Crain, Daiana Stolz, Michael Tamm, Lila Bouadma, Charles E Luyt, Michel Wolff, Jean Chastre, Florence Tubach, Kristina B Kristoffersen, Olaf Burkhardt, Tobias Welte, Stefan Schroeder, Vandack Nobre, Long Wei, Heiner C C Bucher, Neera Bhatnagar, Djillali Annane, Konrad Reinhart, Angela Branche, Pierre Damas, Maarten Nijsten, Dylan W de Lange, Rodrigo O Deliberato, Stella SS Lima, Vera Maravić‐Stojković, Alessia Verduri, Bin Cao, Yahya Shehabi, Albertus Beishuizen, Jens‐Ulrik S Jensen, Caspar Corti, Jos A Van Oers, Ann R Falsey, Evelien de Jong, Carolina F Oliveira, Bianca Beghe, Matthias Briel, Beat Mueller

https://doi.org/10.1002/14651858.CD007498.pub3

2012 Sep 12

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections

Review

Philipp Schuetz, Beat Müller, Mirjam Christ‐Crain, Daiana Stolz, Michael Tamm, Lila Bouadma, Charles E Luyt, Michel Wolff, Jean Chastre, Florence Tubach, Kristina B Kristoffersen, Olaf Burkhardt, Tobias Welte, Stefan Schroeder, Vandack Nobre, Long Wei, Neera Bhatnagar, Heiner C Bucher, Matthias Briel

https://doi.org/10.1002/14651858.CD007498.pub2

2008 Oct 08

Procalcitonin to initiate or withhold antibiotics in acute respiratory tract infections

Protocol

Philipp Schuetz, Matthias Briel, Mirjam Christ‐Crain, Marcel Wolbers, Daiana Stolz, Michael Tamm, Heiner Bucher, Beat Müller

https://doi.org/10.1002/14651858.CD007498

Keywords

MeSH

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.