Ginkgo biloba para la claudicación intermitente
Información
- DOI:
- https://doi.org/10.1002/14651858.CD006888.pub3Copiar DOI
- Base de datos:
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- Cochrane Database of Systematic Reviews
- Versión publicada:
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- 07 junio 2013see what's new
- Tipo:
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- Intervention
- Etapa:
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- Review
- Grupo Editorial Cochrane:
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Grupo Cochrane de Vascular
- Copyright:
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- Copyright © 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Cifras del artículo
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Autores
Contributions of authors
Saskia Nicolaï and Lotte Kruidenier independently selected trials for inclusion, assessed study quality and extracted data. Bianca Bendermacher checked all results for accuracy. Martin Prins and Joep Teijink resolved disagreements. For the 2013 update, Rutger Stokmans and Pieter Broos independently selected trials for inclusion.
Sources of support
Internal sources
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No sources of support supplied
External sources
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Chief Scientist Office, Scottish Government Health Directorates, Scottish Government, UK.
The PVD Group editorial base is supported by the Chief Scientist Office.
Declarations of interest
MP reports his institution has received funds for his Board membership of clinical studies and invited speaker activities from Bayer, Pfizer, Leo, Daichi Sankyo and Sanofi‐Aventis. These were not related to this review.
Acknowledgements
None
Version history
| Published | Title | Stage | Authors | Version |
| 2013 Jun 07 | Ginkgo biloba for intermittent claudication | Review | Saskia PA Nicolaï, Lotte M Kruidenier, Bianca LW Bendermacher, Martin H Prins, Rutger A Stokmans, Pieter PHL Broos, Joep AW Teijink | |
| 2009 Apr 15 | Ginkgo biloba for intermittent claudication | Review | Saskia PA Nicolaï, Lotte M Kruidenier, Bianca LW Bendermacher, Martin H Prins, Joep AW Teijink | |
| 2008 Jan 23 | Ginkgo biloba for intermittent claudication | Protocol | Saskia PA Nicolaï, Lotte M Kruidenier, Bianca LW Bendermacher, Martin H Prins, Joep AW Teijink | |
Notes
This review has been marked stable and will only be updated if new studies are identified.
Keywords
MeSH
Medical Subject Headings (MeSH) Keywords
Medical Subject Headings Check Words
Humans;
PICO
Methodological quality summary: review authors' judgments about each methodological quality item for each included study.
Methodological quality graph: review authors' judgments about each methodological quality item presented as percentages across all included studies.
Forest plot of comparison: 1 Ginkgo biloba versus placebo, outcome: 1.1 Absolute claudication distance (expressed as kilocalories) at the end of the study.
Forest plot of comparison: 1 Ginkgo biloba versus placebo, outcome: 1.2 Absolute claudication distance (expressed as kilocalories) after 24 weeks.
Forest plot of comparison: 1 Ginkgo biloba versus placebo, outcome: 1.3 Absolute claudication distance (expressed as kilocalories) after 12 to 16 weeks.
Forest plot of comparison: 1 Ginkgo biloba versus placebo, outcome: 1.4 Absolute claudication distance (expressed as kilocalories) after 6 to 8 weeks.
Forest plot of comparison: 1 Ginkgo biloba versus placebo, outcome: 1.5 Initial claudication distance (expressed as kilocalories) at the end of the study.
Forest plot of comparison: 1 Ginkgo biloba versus placebo, outcome: 1.6 Initial claudication distance (expressed as kilocalories) after 24 weeks.
Forest plot of comparison: 1 Ginkgo biloba versus placebo, outcome: 1.7 Initial claudication distance (expressed as kilocalories) after 12 to 16 weeks.
Forest plot of comparison: 1 Ginkgo biloba versus placebo, outcome: 1.8 Initial claudication distance (expresses as kilocalories) after 6 to 8 weeks.
Forest plot of comparison: 1 Ginkgo biloba versus placebo, outcome: 1.9 Ankle brachial index and ankle pressure at the end of study.
Forest plot of comparison: 1 Ginkgo biloba versus placebo, outcome: 1.10 Quality of life (expressed as a Visual Analogue Scale for complaints).
Funnel plot of comparison: 1 Ginkgo biloba versus placebo, outcome: 1.1 Absolute claudication distance (expressed as kilocalories) at the end of the study. On the horizontal axis the effect estimate of Ginkgo biloba versus placebo on the absolute claudication distance at the end of the study is presented as the mean difference. The vertical axis presents the standard error of the intervention effect on a reversed scale.
Funnel plot of comparison: 1 Ginkgo biloba versus placebo, outcome: 1.2 Absolute claudication distance (expressed as kilocalories) after 24 weeks. On the horizontal axis the effect estimate of Ginkgo biloba versus placebo on the absolute claudication distance after 24 weeks is presented as the mean difference. The vertical axis presents the standard error of the intervention effect on a reversed scale.
Comparison 1 Ginkgo biloba versus placebo, Outcome 1 Absolute claudication distance (expressed as kilocalories) at the end of the study.
Comparison 1 Ginkgo biloba versus placebo, Outcome 2 Absolute claudication distance (expressed as kilocalories) after 24 weeks.
Comparison 1 Ginkgo biloba versus placebo, Outcome 3 Absolute claudication distance (expressed as kilocalories) after 12 to 16 weeks.
Comparison 1 Ginkgo biloba versus placebo, Outcome 4 Absolute claudication distance (expressed as kilocalories) after 6 to 8 weeks.
Comparison 1 Ginkgo biloba versus placebo, Outcome 5 Initial claudication distance (expressed as kilocalories) at the end of the study.
Comparison 1 Ginkgo biloba versus placebo, Outcome 6 Initial claudication distance (expressed as kilocalories) after 24 weeks.
Comparison 1 Ginkgo biloba versus placebo, Outcome 7 Initial claudication distance (expressed as kilocalories) after 12 to 16 weeks.
Comparison 1 Ginkgo biloba versus placebo, Outcome 8 Initial claudication distance (expresses as kilocalories) after 6 to 8 weeks.
Comparison 1 Ginkgo biloba versus placebo, Outcome 9 Ankle brachial index and ankle pressure at the end of study.
Comparison 1 Ginkgo biloba versus placebo, Outcome 10 Quality of life (expressed as a Visual Analoque Scale for complaints).
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 Absolute claudication distance (expressed as kilocalories) at the end of the study Show forest plot | 11 | 477 | Mean Difference (IV, Random, 95% CI) | 3.57 [‐0.10, 7.23] |
| 2 Absolute claudication distance (expressed as kilocalories) after 24 weeks Show forest plot | 6 | 321 | Mean Difference (IV, Random, 95% CI) | 4.72 [2.27, 7.16] |
| 3 Absolute claudication distance (expressed as kilocalories) after 12 to 16 weeks Show forest plot | 8 | 339 | Mean Difference (IV, Random, 95% CI) | 1.36 [‐2.63, 5.36] |
| 4 Absolute claudication distance (expressed as kilocalories) after 6 to 8 weeks Show forest plot | 5 | 236 | Mean Difference (IV, Random, 95% CI) | 2.19 [‐0.62, 4.99] |
| 5 Initial claudication distance (expressed as kilocalories) at the end of the study Show forest plot | 13 | 723 | Mean Difference (IV, Random, 95% CI) | 1.84 [‐0.92, 4.61] |
| 6 Initial claudication distance (expressed as kilocalories) after 24 weeks Show forest plot | 8 | 564 | Mean Difference (IV, Random, 95% CI) | 2.15 [‐2.06, 6.36] |
| 7 Initial claudication distance (expressed as kilocalories) after 12 to 16 weeks Show forest plot | 9 | 441 | Mean Difference (IV, Random, 95% CI) | 1.54 [‐0.04, 3.12] |
| 8 Initial claudication distance (expresses as kilocalories) after 6 to 8 weeks Show forest plot | 6 | 335 | Mean Difference (IV, Random, 95% CI) | 2.72 [0.75, 4.69] |
| 9 Ankle brachial index and ankle pressure at the end of study Show forest plot | 6 | 274 | Std. Mean Difference (IV, Random, 95% CI) | ‐0.22 [‐0.58, 0.15] |
| 10 Quality of life (expressed as a Visual Analoque Scale for complaints) Show forest plot | 5 | 208 | Std. Mean Difference (IV, Random, 95% CI) | 0.38 [‐0.94, 1.70] |
