Tirilazad for aneurysmal subarachnoid haemorrhage
Appendices
Appendix 1. MEDLINE and CENTRAL search strategy
MEDLINE (Ovid) and CENTRAL
1. Intracranial Aneurysm/
2. exp Intracranial Hemorrhages/
3. aneurysm/ or aneurysm, ruptured/ or aneurysm, dissecting/
4. exp brain/ or exp carotid arteries/ or basilar artery/ or exp carotid artery diseases/ or exp cerebral arteries
5. 3 and 4
6. ((brain$ or cerebral or intracerebral or intracranial or cerebell$ or intraventricular or parenchymal or infratentorial or supratentorial or subarachnoid or carotid or communicating or gaint or basilar) adj10 (aneurysm$ or hemorrhage$ or haemorrhage$ or hematoma$ or haematoma$ or bleed$)).tw.
7. 1 or 2 or 5 or 6
8. pregnatrienes/
9.(tirilazad or freedox or tridax or tridox or u74006$ or u‐74006$ or u 74006$ or lazaroid$ or aminosteroid$ or 21‐aminosteroid$).tw.
10. 8 or 9
11. 7 and 10
Appendix 2. EMBASE search strategy
EMBASE (Ovid)
1. intracranial aneurysm/ or brain artery aneurysm/ or brain artery aneurysm rupture/
2. exp carotid artery aneurysm/ or exp brain hematoma/ or exp brain hemorrhage/
3. aneurysm/ or aneurysm rupture/ or dissecting aneurysm/
4. exp brain/ or exp brain artery/ or exp carotid artery/ or exp carotid artery disease/
5. 3 and 4
6. ((brain$ or cerebral or intracerebral or intracranial or cerebell$ or intraventricular or parenchymal or infratentorial or supratentorial or subarachnoid or carotid or communicating or gaint or basilar) adj10 (aneurysm$ or hemorrhage$ or haemorrhage$ or hematoma$ or haematoma$ or bleed$)).tw.
7. 1 or 2 or 5 or 6
8. Tirilazad/ or Pregnane derivative/ or 21 Aminosteroid/ or Lazaroid/
9. (tirilazad or freedox or tridax or tridox or u74006$ or u‐74006$ or u 74006$ or lazaroid$ or aminosteroid$ or 21‐aminosteroid$).tw.
10. 8 or 9
11. 7 and 10
