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Home‐based therapy programmes for upper limb functional recovery following stroke

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Background

With an increased focus on home‐based stroke services and the undertaking of programmes, targeted at upper limb recovery within clinical practice, a systematic review of home‐based therapy programmes for individuals with upper limb impairment following stroke was required.

Objectives

To determine the effects of home‐based therapy programmes for upper limb recovery in patients with upper limb impairment following stroke.

Search methods

We searched the Cochrane Stroke Group's Specialised Trials Register (May 2011), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2011, Issue 2), MEDLINE (1950 to May 2011), EMBASE (1980 to May 2011), AMED (1985 to May 2011) and six additional databases. We also searched reference lists and trials registers.

Selection criteria

Randomised controlled trials (RCTs) in adults after stroke, where the intervention was a home‐based therapy programme targeted at the upper limb, compared with placebo, or no intervention or usual care. Primary outcomes were performance in activities of daily living (ADL) and functional movement of the upper limb. Secondary outcomes were performance in extended ADL and motor impairment of the arm.

Data collection and analysis

Two review authors independently screened abstracts, extracted data and appraised trials. We undertook assessment of risk of bias in terms of method of randomisation and allocation concealment (selection bias), blinding of outcome assessment (detection bias), whether all the randomised patients were accounted for in the analysis (attrition bias) and the presence of selective outcome reporting.

Main results

We included four studies with 166 participants. No studies compared the effects of home‐based upper limb therapy programmes with placebo or no intervention. Three studies compared the effects of home‐based upper limb therapy programmes with usual care. Primary outcomes: we found no statistically significant result for performance of ADL (mean difference (MD) 2.85; 95% confidence interval (CI) ‐1.43 to 7.14) or functional movement of the upper limb (MD 2.25; 95% CI ‐0.24 to 4.73)). Secondary outcomes: no statistically significant results for extended ADL (MD 0.83; 95% CI ‐0.51 to 2.17)) or upper limb motor impairment (MD 1.46; 95% CI ‐0.58 to 3.51). One study compared the effects of a home‐based upper limb programme with the same upper limb programme based in hospital, measuring upper limb motor impairment only; we found no statistically significant difference between groups (MD 0.60; 95% CI ‐8.94 to 10.14).

Authors' conclusions

There is insufficient good quality evidence to make recommendations about the relative effect of home‐based therapy programmes compared with placebo, no intervention or usual care.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.

Plain language summary

Home‐based therapy programmes for upper limb functional recovery after stroke

After a stroke, upper limb (arm) problems are common and recovery is often limited. This review of four studies with 166 relevant participants, looked at whether participating in home‐based therapy programmes, targeted at the upper limb, could improve performance in activities of daily living (ADL), functional movement of the upper limb, performance in extended ADL and arm motor impairment. In comparison with usual care, home‐based upper limb programmes had no difference in effect on any of the outcomes. In comparison with an upper limb programme based in hospital, we found home‐based upper limb programmes to be no more or no less effective for arm motor impairment outcomes. The evidence in this area is limited. Further research is needed to determine the effects of home‐based therapy programmes.