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Cochrane Database of Systematic Reviews

Kineski biljni lijekovi za osobe s poremećenom tolerancijom glukoze ili poremećenom razinom glukoze natašte

Información

DOI:
https://doi.org/10.1002/14651858.CD006690.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 06 octubre 2009see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Trastornos metabólicos y endocrinos

Copyright:
  1. Copyright © 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Contraer

Autores

  • Suzanne J Grant

    Correspondencia a: University of Western Sydney, South DC, Australia

    [email protected]

  • Alan Bensoussan

    Center for Complementary Medicine Research, University of Western Sydney, Sydney, Australia

  • Dennis Chang

    Center for Complementary Medicine Research, University of Western Sydney, Sydney, Australia

  • Hosen Kiat

    Cardiac Health Institute, Eastwood, Australia

  • Nerida L Klupp

    Center for Complementary Medicine Research, University of Western Sydney, Sydney, Australia

  • Jian Ping Liu

    Centre for Evidence‐Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China

  • Xun Li

    Centre for Evidence‐Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China

Contributions of authors

Conceiving the review: SG
Designing the review: SG, JL, NK, DC, AB, HK
Coordinating the review: SG
Undertaking manual searches: SG, JL, XL
Screening search results: SG, JL, XL
Organising retrieval of papers: SG, JL, XL
Screening retrieved papers against inclusion criteria: SG, JL
Appraising quality of papers: SG, JL
Abstracting data from papers: SG, JL, XL
Writing to authors of papers for additional information: SG, JL, XL
Obtaining and screening data on unpublished studies: SG, JL, XL
Data management for the review: SG
Entering data into RevMan: SG
Analysis of data: SG
Interpretation of data: SG, JL
Writing the review: SG, JL, XL, NK, DC, AB, HK
Securing funding for the review: SG, DC, AB, HK
Guarantor for the review (one author): Suzanne Grant

Sources of support

Internal sources

  • No sources of support supplied

External sources

  • University of Western Sydney, Australia.

  • Cardiac Health Institute, Australia.

Declarations of interest

Suzanne Grant is currently undertaking a randomised controlled trial of Chinese herbal medicines to treat impaired glucose tolerance or impaired fasting blood glucose. There are no other known potential conflicts of interest.

Acknowledgements

This work was partially funded by Grant Number R24 AT001293 from the National Center for Complementary and Alternative Medicine (NCCAM) and the Cardiac Health Institute. The contents of this systematic review are solely the responsibility of the authors and do not necessarily represent the official views of the NCCAM or the National Institutes of Health.

Version history

Published

Title

Stage

Authors

Version

2009 Oct 06

Chinese herbal medicines for people with impaired glucose tolerance or impaired fasting blood glucose

Review

Suzanne J Grant, Alan Bensoussan, Dennis Chang, Hosen Kiat, Nerida L Klupp, Jian Ping Liu, Xun Li

https://doi.org/10.1002/14651858.CD006690.pub2

2009 Jul 08

Chinese herbal medicines for people with impaired glucose tolerance or impaired fasting blood glucose

Protocol

Suzanne J Grant, Alan Bensoussan, Dennis Chang, Hosen Kiat, Nerida L Klupp, Jian Ping Liu

https://doi.org/10.1002/14651858.CD006690

Differences between protocol and review

We chose to alter the way in which the assessment of methodological quality was conducted and focus on a risk of bias assessment as a more useful analysis of the individual trials rather than using the tool originally described in the protocol.

Rather than using fixed effect modelling for continuous data as per the protocol the authors determined that a random‐effects model was more appropriate for the relatively heterogeneous nature of herbal medicines. It would not be expected that different herbal formulations would produce the same quantity but that the different interventions would produce a distribution in magnitude of effects on any given outcome.

Dichotomous data were expressed as relative risk (RR) ratios rather than odds ratios (OR). This method has been changed since the publication of the protocol to reflect the approach used by other studies in this modality of treatment. It is also a more easily understood statistic in presenting these outcomes.

A high level of statistical heterogeneity was found in the comparison of Chinese herbal medicines with lifestyle modification vs lifestyle modification alone on nearly all outcomes. For this reason subgroup analyses were undertaken. Due to the nature of the trials included the subgroup analyses varied from those set out in the trial protocol.

The database CISCOM was not searched as it is no longer active.