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Cochrane Database of Systematic Reviews

Hipotensión deliberada con propofol bajo anestesia para la cirugía funcional endoscópica de senos paranasales (CFES)

Información

DOI:
https://doi.org/10.1002/14651858.CD006623.pub3Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 12 octubre 2016see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Anestesia

Copyright:
  1. Copyright © 2016 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Autores

  • Polpun Boonmak

    Correspondencia a: Department of Anaesthesiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

    [email protected]

    [email protected]

  • Suhattaya Boonmak

    Department of Anaesthesiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

  • Malinee Laopaiboon

    Department of Epidemiology and Biostatistics, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand

Contributions of authors

Polpun Boonmak (PB), Suhattaya Boonmak (SB), Malinee Laopaiboon (ML)

Conceiving the review: PB, SB
Co‐ordinating the review: PB, BS, ML
Undertaking manual searches: PB, SB
Screening search results: PB, SB
Organizing retrieval of papers: PB, SB
Screening retrieved papers against inclusion criteria: PB, SB
Appraising quality of papers: PB, SB
Abstracting data from papers: PB, SB
Writing to authors of papers for additional information: PB, SB
Providing additional data about papers: PB, SB
Obtaining and screening data on unpublished studies: PB, SB
Providing data management for the review: PB, SB, ML
Entering data into Review Manager (RevMan 5.3): PB, SB
Obtaining RevMan statistical data: PB, SB, ML
Performing other statistical analysis while not using RevMan: ML
Performing double entry of data: (data entered by person one: PB; data entered by person two: SB)
Interpreting data: ML
Making statistical inferences: ML
Writing the review: PB, SB, ML
Securing funding for the review: PB
Performing previous work that served as the foundation of the present study: PB, SB
Serving as guarantor for the review (one author): PB
Taking responsibility for reading and checking review before submission: PB, SB

Sources of support

Internal sources

  • Systematic review grant, Faculty of Medicine, Khon Kaen University, Thailand.

  • Thai Cochrane Network, Thailand.

External sources

  • The Thailand Research Fund, Thailand.

Declarations of interest

Polpun Boonmak: none known.

Suhattaya Boonmak: none known.

Malinee Laopaiboon: received an honorarium from Thailand Research Fund, a nonprofit organization, in 2014.

Acknowledgements

We would like to thank Jane Cracknell for her help and editorial advice during the preparation of this review update.

We would like to thank Mike Bennett (content editor) and James W Fairley and Leopold Eberhart (peer reviewers) for their help and editorial advice during the preparation of the protocol for this systematic review (Boonmak 2007). We also thank Karen Hovhannisyan for his search strategy and data searching.

We would like to thank Jane Cracknell, Mike Bennett (content editor), Marialena Trivella (statistical editor), James W Fairley and Leopold Eberhart (peer reviewers), and Katriona Methven (representative of the Cochrane Consumer Network) for their help and editorial advice during the preparation of the previous version of this review (Boonmak 2013).

Version history

Published

Title

Stage

Authors

Version

2016 Oct 12

Deliberate hypotension with propofol under anaesthesia for functional endoscopic sinus surgery (FESS)

Review

Polpun Boonmak, Suhattaya Boonmak, Malinee Laopaiboon

https://doi.org/10.1002/14651858.CD006623.pub3

2013 Jun 06

Deliberate hypotension with propofol under anaesthesia for functional endoscopic sinus surgery (FESS)

Review

Suhattaya Boonmak, Polpun Boonmak, Malinee Laopaiboon

https://doi.org/10.1002/14651858.CD006623.pub2

2007 Jul 18

Deliberate hypotension with propofol under anaesthesia for functional endoscopic sinus surgery (FESS)

Protocol

Suhattaya Boonmak, Polpun Boonmak, Malinee Laopaiboon

https://doi.org/10.1002/14651858.CD006623

Differences between protocol and review

We made the following changes to the protocol (Boonmak 2007).

  1. The quality of surgical field grading was changed from "good, fair, poor" to 6‐point scale surgical field.

  2. Principal author in this update (2016) is Polpun Boonmak.

Keywords

MeSH

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.

Study flow diagram.
Figuras y tablas -
Figure 1

Study flow diagram.

Methodological quality summary: review authors' judgements about each methodological quality item for each included study.
Figuras y tablas -
Figure 2

Methodological quality summary: review authors' judgements about each methodological quality item for each included study.

Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
Figuras y tablas -
Figure 3

Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.

Comparison 1 Propofol versus inhalation anaesthetics, Outcome 1 Quality of surgical field (age group).
Figuras y tablas -
Analysis 1.1

Comparison 1 Propofol versus inhalation anaesthetics, Outcome 1 Quality of surgical field (age group).

Comparison 1 Propofol versus inhalation anaesthetics, Outcome 2 Operation time (minutes).
Figuras y tablas -
Analysis 1.2

Comparison 1 Propofol versus inhalation anaesthetics, Outcome 2 Operation time (minutes).

Summary of findings for the main comparison. Propofol versus inhalation anaesthetics for functional endoscopic sinus surgery (FESS)

Propofol versus inhalation anaesthetics for functional endoscopic sinus surgery (FESS)

Patient or population: patients undergoing FESS
Settings: operating rooms in Asia, Australia, and Europe
Intervention: propofol versus inhalation anaesthetics

Outcomes

Illustrative comparative risks* (95% CI)

Relative effect
(95% CI)

No of Participants
(studies)

Quality of the evidence
(GRADE)

Comments

Assumed risk

Corresponding risk

Control

Propofol versus inhalation anaesthetics

Total blood loss ‐ children

The mean total blood loss was 120 mL

The mean total blood loss was 20 lower (0.77 to 39.23 lower)

70 (1 study)

⊕⊝⊝⊝
very low1

Total blood loss ‐ adults

The median total blood loss was 170 mL

The median total blood loss was 100 mL (interquartile range 50 to 240 mL)

88 (1 study)

⊕⊕⊕⊝
moderate2

Quality of surgical field
Scale from 0 to 5

The mean quality of surgical field in the control groups was
2.55

The mean quality of surgical field in the intervention groups was
0.64 lower (0.37 to 0.91 lower)

277
(4 studies)

⊕⊕⊝⊝
low3

Operation time

The mean operation time in the control groups was 91.51 min

The mean operation time in the intervention groups was
4.81 lower
(11.82 lower to 2.21 higher)

214
(3 studies)

⊕⊕⊝⊝
low4

Failure of deliberate hypotension (%)

372 per 1000

89 per 1000
(33 to 246)

RR 0.24
(0.09 to 0.66)

88
(1 study)

⊕⊕⊕⊝
moderate2

*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval; RR: risk ratio

GRADE Working Group grades of evidence
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: We are very uncertain about the estimate.

1Downgraded three levels due to concerns about random sequence generation, allocation concealment and very wide confidence interval for the difference.

2Downgraded one level due to concerns about random sequence generation.

3Downgraded two levels due to serious concerns about random sequence generation, and allocation concealment.

4Downgraded two levels due to serious concerns about random sequence generation, and allocation concealment.

Figuras y tablas -
Summary of findings for the main comparison. Propofol versus inhalation anaesthetics for functional endoscopic sinus surgery (FESS)
Comparison 1. Propofol versus inhalation anaesthetics

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Quality of surgical field (age group) Show forest plot

4

277

Mean Difference (IV, Random, 95% CI)

‐0.64 [‐0.91, ‐0.37]

1.1 Adult

3

207

Mean Difference (IV, Random, 95% CI)

‐0.75 [‐1.10, ‐0.40]

1.2 Children

1

70

Mean Difference (IV, Random, 95% CI)

‐0.40 [‐0.64, ‐0.16]

2 Operation time (minutes) Show forest plot

3

214

Mean Difference (IV, Fixed, 95% CI)

‐4.81 [‐11.82, 2.21]

2.1 Adult

2

144

Mean Difference (IV, Fixed, 95% CI)

3.89 [‐9.64, 17.42]

2.2 Children

1

70

Mean Difference (IV, Fixed, 95% CI)

‐8.0 [‐16.20, 0.20]

Figuras y tablas -
Comparison 1. Propofol versus inhalation anaesthetics