Concomitant hyperthermia and radiation therapy for treating locally advanced rectal cancer

Scolaris Content Display Scolaris Content Display

Ir a:

Figure 1

Analysis 1.1

Comparison 1 RT versus RT and HT, Outcome 1 Overall survival (2‐5 year).

Analysis 1.2

Comparison 1 RT versus RT and HT, Outcome 2 Local tumor recurrence (2 and 3 year).

Analysis 1.3

Comparison 1 RT versus RT and HT, Outcome 3 Complete response.

Comparison 1. RT versus RT and HT

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Overall survival (2‐5 year) Show forest plot	4		Peto Odds Ratio (Peto, Fixed, 95% CI)	Subtotals only

1.1 2 year (death within 2 years)	4	424	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.49 [0.32, 0.75]
1.2 3 year (death within 3 years)	4	424	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.93 [0.55, 1.58]
1.3 4 year (death within 4 years)	2	216	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.99 [0.89, 4.45]
1.4 5 year (death within 5 years)	1	115	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.50 [0.19, 1.34]
2 Local tumor recurrence (2 and 3 year) Show forest plot	4		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only

2.1 2 year	3	180	Risk Ratio (M‐H, Fixed, 95% CI)	1.23 [0.92, 1.65]
2.2 3 year	2	236	Risk Ratio (M‐H, Fixed, 95% CI)	1.07 [0.76, 1.49]
3 Complete response Show forest plot	5	506	Risk Ratio (M‐H, Fixed, 95% CI)	2.67 [1.63, 4.38]

Comparison 1. RT versus RT and HT