Methods

1.5 year postloading, randomised parallel group study. No drop outs.

Participants

Patients with a single tooth to be replaced by a single‐tooth implant in the maxillary anterior and premolar region. Adults treated at the ACTA, University of Amsterdam, The Netherlands. Patients were excluded if were medically compromised, if smokers, or if a primary implant stability of 25 Ncm could not be achieved. 25 patients enrolled in each group.

Interventions

Immediate (same day) versus delayed (3 months on average) implants after extractions of periapically infected single teeth. Implants were placed 2 mm below the cervical junction of the adjacent teeth. Autogenous bone grafts from the trigonum retromolar or chin region were covered with a bioresorbable collagen membrane (Bio‐Gide, Geistlich AG, Wolhusen, Switzerland) in all patients and the implants were submerged and left healing for 6 months. Single crowns were cemented with temporary cement. All implants were Frialit‐2 Synchro (Dentsply Friadent Ceramed, Mannheim, Germany).

Outcomes

Prosthesis failure, implant failure, complications, perimplant marginal bone level changes on intraoral radiographs, pocket probing depth, patient satisfaction, aesthetics assessed by a blinded outcome assessor (interproximal papilla dimensions and mid‐buccal perimplant gingival levels).

Notes

Risk of bias

Bias

Authors' judgement

Support for judgement

Allocation concealment?

Low risk

A ‐ Adequate

Methods

1.5 year postloading, randomised parallel group study. 2 drop outs, 1 from each group for not having paid the treatment.

Participants

Patients with a single tooth to be replaced by a single‐tooth implant in the anterior and premolar region of both mandibles and maxillas. Adults treated at the Royal Dental College, University of Århus, Denmark. Patients were excluded if were medically compromised (metabolic diseases, immune deficient or under immune‐suppressive therapy, irradiated, etc.) or if they had insufficient bone to achieve primary stability of the implant. 23 patients enrolled in each group.

Interventions

Delayed immediate (10 days on average) versus delayed implants (3 months on average) after extractions of compromised single teeth. Autogenous bone grafting was done when implants threads were exposed at abutment connection for immediate‐delayed implants and at both implant placement and at abutment connection for delayed implants. Implants were submerged and left to heal for about 3 months. Single‐tooth metal‐ceramic crowns were provided. All implants were Osseotite (3i Implamt Innovations Inc., Palm Beach Gardens, FL, USA)

Outcomes

Prosthesis failure, implant failure, complications, various bone measures at implantation and abutment connection, perimplant marginal bone level changes on intraoral radiographs, pocket probing depth, patient satisfaction, aesthetics assessed by patients and by an independent experienced prosthodontist (interproximal papilla dimensions and the mid‐buccal gingival level), resonace frequency stability assessed with Ostell, and microbiologic evaluation.

Notes

Risk of bias

Bias

Authors' judgement

Support for judgement

Allocation concealment?

Low risk

A ‐ Adequate