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Cochrane Database of Systematic Reviews

以Omega 3脂肪酸預防認知能力下降與失智症

Información

DOI:
https://doi.org/10.1002/14651858.CD005379.pub3Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 13 junio 2012see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Demencia y trastornos cognitivos

Copyright:
  1. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Autores

  • Emma Sydenham

    Correspondencia a: Cochrane Injuries Group, London School of Hygiene & Tropical Medicine, London, UK

    [email protected]

  • Alan D Dangour

    Department of Nutrition and Public Health Intervention Research, London School of Hygiene & Tropical Medicine, London, UK

  • Wee‐Shiong Lim

    Department of Geriatric Medicine, Tan Tock Seng Hospital, Singapore, Singapore

Contributions of authors

Contribution to the first published version (2006):
Wee‐Shiong Lim led the review team, screened the search for studies, and took the lead in drafting the manuscript. Julie Gammack and Jan Van Niekerk assisted in searching for studies and sought to identify studies for inclusion by screening the search results. All authors provided intellectual input into the final version of the review.

Contribution to the 2012 update:
Emma Sydenham (ES), Wee‐Shiong Lim (W‐S L), and Alan Dangour (AD) screened the search results and selected studies for inclusion. AD contacted experts in the field, sought additional data from included study investigators, and re‐wrote the Background section. ES contacted omega‐3 manufacturers for additional data; the data were reviewed by AD and W‐S L. ES extracted data from the study reports, entered the data into RevMan, assessed the risk of bias in included studies, undertook the analysis, and updated the text of the review; W‐S L checked for accuracy. All authors contributed to the final version of the manuscript. No sources of support are listed as all authors contributed to this review in their own time.

Declarations of interest

Alan Dangour is the principal investigator of Dangour 2010 (the Older People And n‐3 Long‐chain polyunsaturated fatty acids (OPAL) study).

ES and W‐S L: None known.

Acknowledgements

We acknowledge the work of Julie K Gammack and Jan Van Niekerk who contributed to the original protocol and first version of this review (published in 2006).

Anna Noel‐Storr, Trials Search Coordinator of the Cochrane Dementia and Cognitive Improvement Group designed the search strategy, undertook the electronic search for studies, and performed the initial screening of the search results.

We thank the anonymous peer referees for volunteering to comment on the manuscript, and the study investigators for providing additional data and information.

Version history

Published

Title

Stage

Authors

Version

2012 Jun 13

Omega 3 fatty acid for the prevention of cognitive decline and dementia

Review

Emma Sydenham, Alan D Dangour, Wee‐Shiong Lim

https://doi.org/10.1002/14651858.CD005379.pub3

2006 Jan 25

Omega 3 fatty acid for the prevention of dementia

Review

Wee‐Shiong Lim, Julie K Gammack, Jan K Van Niekerk, Alan Dangour

https://doi.org/10.1002/14651858.CD005379.pub2

2005 Jul 20

Omega 3 fatty acid for the prevention of dementia

Protocol

Wee‐Shiong Lim, Julie K Gammack, Jan Van Niekerk, Alan Dangour

https://doi.org/10.1002/14651858.CD005379

Differences between protocol and review

The methods of the review were updated to comply with the most recent version of the Cochrane Handbook for Systematic Reviews of Interventions (Version 5.1 March 2011) and the Cochrane Collaboration's Methodological Expectations of Cochrane Intervention Reviews criteria (November 2011).

The analysis of secondary outcomes was changed from mean change from baseline to difference between intervention groups at final follow‐up (Handbook section 7.7.3.1).

The secondary outcomes health‐related quality of life, depression, and anxiety which are listed in the protocol have been removed from this review. These outcomes have been assessed elsewhere (Appleton 2010).

Notes

Future updates of this review will include participants age 50 years and over.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.