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Comparison 1 Any Psychosocial plus any Pharmacological detoxification Intervention versus any Pharmachological alone, Outcome 1 Completion of treatment.
Figuras y tablas -
Analysis 1.1

Comparison 1 Any Psychosocial plus any Pharmacological detoxification Intervention versus any Pharmachological alone, Outcome 1 Completion of treatment.

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Comparison 1 Any Psychosocial plus any Pharmacological detoxification Intervention versus any Pharmachological alone, Outcome 2 Use of primary substance.
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Analysis 1.2

Comparison 1 Any Psychosocial plus any Pharmacological detoxification Intervention versus any Pharmachological alone, Outcome 2 Use of primary substance.

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Comparison 1 Any Psychosocial plus any Pharmacological detoxification Intervention versus any Pharmachological alone, Outcome 3 Number of subjects abstinent at follow‐up.
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Analysis 1.3

Comparison 1 Any Psychosocial plus any Pharmacological detoxification Intervention versus any Pharmachological alone, Outcome 3 Number of subjects abstinent at follow‐up.

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Comparison 2 Any Psychosocial Intervention plus MDT versus MDT alone, Outcome 1 Completion of treatment.
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Analysis 2.1

Comparison 2 Any Psychosocial Intervention plus MDT versus MDT alone, Outcome 1 Completion of treatment.

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Comparison 2 Any Psychosocial Intervention plus MDT versus MDT alone, Outcome 2 Use of primary substance.
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Analysis 2.2

Comparison 2 Any Psychosocial Intervention plus MDT versus MDT alone, Outcome 2 Use of primary substance.

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Comparison 2 Any Psychosocial Intervention plus MDT versus MDT alone, Outcome 3 Number of subjects abstinent at follow‐up.
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Analysis 2.3

Comparison 2 Any Psychosocial Intervention plus MDT versus MDT alone, Outcome 3 Number of subjects abstinent at follow‐up.

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Comparison 2 Any Psychosocial Intervention plus MDT versus MDT alone, Outcome 4 Compliance as clinic absences during the treatment.
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Analysis 2.4

Comparison 2 Any Psychosocial Intervention plus MDT versus MDT alone, Outcome 4 Compliance as clinic absences during the treatment.

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Comparison 3 Contingency Management Approaches plus MDT versus MDT alone, Outcome 1 Completion of treatment.
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Analysis 3.1

Comparison 3 Contingency Management Approaches plus MDT versus MDT alone, Outcome 1 Completion of treatment.

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Comparison 3 Contingency Management Approaches plus MDT versus MDT alone, Outcome 2 Compliance as clinical absences during the treatment.
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Analysis 3.2

Comparison 3 Contingency Management Approaches plus MDT versus MDT alone, Outcome 2 Compliance as clinical absences during the treatment.

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Comparison 1. Any Psychosocial plus any Pharmacological detoxification Intervention versus any Pharmachological alone

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Completion of treatment Show forest plot

5

184

Risk Ratio (M‐H, Fixed, 95% CI)

1.68 [1.11, 2.55]

2 Use of primary substance Show forest plot

3

109

Risk Ratio (M‐H, Fixed, 95% CI)

0.77 [0.59, 1.01]

3 Number of subjects abstinent at follow‐up Show forest plot

3

208

Risk Ratio (M‐H, Fixed, 95% CI)

2.43 [1.61, 3.66]
Figuras y tablas -
Comparison 1. Any Psychosocial plus any Pharmacological detoxification Intervention versus any Pharmachological alone
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Comparison 2. Any Psychosocial Intervention plus MDT versus MDT alone

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Completion of treatment Show forest plot

4

145

Risk Ratio (M‐H, Fixed, 95% CI)

1.48 [0.93, 2.35]

2 Use of primary substance Show forest plot

2

70

Risk Ratio (M‐H, Fixed, 95% CI)

0.69 [0.44, 1.07]

3 Number of subjects abstinent at follow‐up Show forest plot

2

169

Risk Ratio (M‐H, Fixed, 95% CI)

2.46 [1.61, 3.76]

4 Compliance as clinic absences during the treatment Show forest plot

3

1138

Risk Ratio (M‐H, Fixed, 95% CI)

0.48 [0.38, 0.59]
Figuras y tablas -
Comparison 2. Any Psychosocial Intervention plus MDT versus MDT alone
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Comparison 3. Contingency Management Approaches plus MDT versus MDT alone

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Completion of treatment Show forest plot

3

95

Risk Ratio (M‐H, Fixed, 95% CI)

1.51 [0.93, 2.46]

2 Compliance as clinical absences during the treatment Show forest plot

2

196

Risk Ratio (M‐H, Fixed, 95% CI)

0.29 [0.15, 0.56]
Figuras y tablas -
Comparison 3. Contingency Management Approaches plus MDT versus MDT alone
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