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Comparison 1 Valerian vs placebo, Outcome 1 Reduction in anxiety symptoms (HAM‐A).
Figuras y tablas -
Analysis 1.1

Comparison 1 Valerian vs placebo, Outcome 1 Reduction in anxiety symptoms (HAM‐A).

Comparison 1 Valerian vs placebo, Outcome 2 Reduction in anxiety symptoms (STAI‐T).
Figuras y tablas -
Analysis 1.2

Comparison 1 Valerian vs placebo, Outcome 2 Reduction in anxiety symptoms (STAI‐T).

Comparison 1 Valerian vs placebo, Outcome 3 Side effects.
Figuras y tablas -
Analysis 1.3

Comparison 1 Valerian vs placebo, Outcome 3 Side effects.

Comparison 1 Valerian vs placebo, Outcome 4 Overall dropout.
Figuras y tablas -
Analysis 1.4

Comparison 1 Valerian vs placebo, Outcome 4 Overall dropout.

Comparison 2 Valerian vs diazepam, Outcome 1 Reduction in anxiety symptoms (HAM‐A).
Figuras y tablas -
Analysis 2.1

Comparison 2 Valerian vs diazepam, Outcome 1 Reduction in anxiety symptoms (HAM‐A).

Comparison 2 Valerian vs diazepam, Outcome 2 Reduction in anxiety symptoms (STAI‐T).
Figuras y tablas -
Analysis 2.2

Comparison 2 Valerian vs diazepam, Outcome 2 Reduction in anxiety symptoms (STAI‐T).

Comparison 2 Valerian vs diazepam, Outcome 3 Side effects.
Figuras y tablas -
Analysis 2.3

Comparison 2 Valerian vs diazepam, Outcome 3 Side effects.

Comparison 2 Valerian vs diazepam, Outcome 4 Overall dropout.
Figuras y tablas -
Analysis 2.4

Comparison 2 Valerian vs diazepam, Outcome 4 Overall dropout.

Comparison 1. Valerian vs placebo

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Reduction in anxiety symptoms (HAM‐A) Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

1.1 total score

1

24

Mean Difference (IV, Fixed, 95% CI)

‐1.40 [‐7.93, 5.13]

1.2 somatic factor

1

24

Mean Difference (IV, Fixed, 95% CI)

0.40 [‐3.12, 3.92]

1.3 psychic factor

1

24

Mean Difference (IV, Fixed, 95% CI)

‐1.80 [‐6.22, 2.62]

2 Reduction in anxiety symptoms (STAI‐T) Show forest plot

1

24

Mean Difference (IV, Fixed, 95% CI)

0.70 [‐9.93, 11.33]

3 Side effects Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

3.1 Somnolence

1

24

Risk Ratio (M‐H, Fixed, 95% CI)

0.33 [0.01, 7.45]

4 Overall dropout Show forest plot

1

24

Risk Ratio (M‐H, Fixed, 95% CI)

1.0 [0.17, 5.98]

Figuras y tablas -
Comparison 1. Valerian vs placebo
Comparison 2. Valerian vs diazepam

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Reduction in anxiety symptoms (HAM‐A) Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

1.1 total score

1

24

Mean Difference (IV, Fixed, 95% CI)

0.40 [‐6.22, 7.02]

1.2 somatic factor

1

24

Mean Difference (IV, Fixed, 95% CI)

‐0.20 [‐2.93, 2.53]

1.3 psychic factor

1

24

Mean Difference (IV, Fixed, 95% CI)

0.60 [‐3.82, 5.02]

2 Reduction in anxiety symptoms (STAI‐T) Show forest plot

1

24

Mean Difference (IV, Fixed, 95% CI)

11.40 [1.90, 20.90]

3 Side effects Show forest plot

1

24

Risk Ratio (M‐H, Fixed, 95% CI)

0.33 [0.01, 7.45]

4 Overall dropout Show forest plot

1

24

Risk Ratio (M‐H, Fixed, 95% CI)

1.0 [0.17, 5.98]

Figuras y tablas -
Comparison 2. Valerian vs diazepam