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Incisiones quirúrgicas abdominales para la operación cesárea

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Referencias

Referencias de los estudios incluidos en esta revisión

Berthet 1989 {published and unpublished data}

Berthet J, Peresse JF, Rosier P, Racinet C. Comparative study of Pfannenstiel's incision and transverse abdominal incision in gynecologic and obstetric surgery [Etude comparative de l'incision de Pfannenstiel et de i'incision transversale transmusculaire en chirurgie gynecologique et obstetricale]. Presse Medicale 1989;18(29):1431‐3.

Franchi 2002 {published data only (unpublished sought but not used)}

Franchi M, Ghezzi F, Raio L, Di Naro E, Miglierina M, Agosti M, et al. Joel‐Cohen or Pfannenstiel incision at cesarean delivery: does it make a difference?. Acta Obstetricia et Gynecologica Scandinavica 2002;81:1040‐6.
Ghezzi F, Franchi F, Raio L, Di Naro E, Balestreri D, Miglierina M, et al. Pfanenstiel or Joel‐Cohen incision at cesarean delivery: a randomized clinical trial. American Journal of Obstetrics and Gynecology 2001;184(1):S166.

Giacalone 2002 {published data only (unpublished sought but not used)}

Giacalone PL, Daures JP, Vignal J, Herisson C, Hedon B, Laffargue F. Pfannenstiel versus Maylard incision for cesarean delivery: a randomized controlled trial. Obstetrics and Gynecology 2002;99:745‐50.

Mathai 2002 {published data only}

Mathai M, Ambersheth S, George A. Comparison of two transverse abdominal incisions for cesarean delivery. International Journal of Gynecology & Obstetrics 2002;78:47‐9.

Referencias de los estudios excluidos de esta revisión

Ansaloni 2001 {published data only}

Ansaloni L, Brundisini R, Morino G, Kiura A. Prospective, randomized, comparative study of Misgav‐Ladach versus traditional cesarean section at Nazareth Hospital, Kenya. World Journal of Surgery 2001;25(9):1164‐72.

Ayers 1987 {published data only}

Ayers JWT, Morley GW. Surgical incision for cesarean section. Obstetrics and Gynecology 1987;70:706‐8.

Ayres‐de‐Campos 2000 {published data only}

Ayres‐de‐Campos D, Patricio B. Modifications to the misgav ladach technique for cesarean section [letter]. Acta Obstetricia et Gynecologica Scandinavica 2000;79:326‐7.

Behrens 1997 {published data only}

Behrens D, Zimmerman S, Stoz F, Holzgreve W. Conventional versus cohen‐stark: a randomised comparison of the two techniques for cesarean section. 20th Congress of the Swiss Society of Gynecology and Obstetrics; 1997 June; Lugano, Switzerland. 1997:14.

Bjorklund 2000 {published and unpublished data}

Bjorklund K, Kimaro M, Urassa E, Lindmark G. Introduction of the Misgav Ladach caesarean section at an African tertiary centre: a randomised controlled trial. BJOG: an international journal of obstetrics and gynaecology 2000;107:209‐16.

Dani 1998 {published and unpublished data}

Dani C, Reali MF, Oliveto R, Temporin GF, Bertini G, Rubaltelli FF. Short‐term outcome of newborn infants born by a modified procedure of cesarean section. Acta Obstetricia et Gynecologica Scandinavica 1998;77:929‐31.

Darj 1999 {published and unpublished data}

Darj E, Nordstrom ML. The Misgav Ladach method for cesarean section compared to the Pfannenstiel method. Acta Obstetricia et Gynecologica Scandinavica 1999;78:37‐41.

Decavalas 1997 {published data only}

Decavalas G, Papadopoulos V, Tzingounis V. A prospective comparison of surgical procedures in cesarean section. Acta Obstetricia et Gynecologica Scandinavica 1997;76(167):13.

Direnzo 2001 {published data only}

Direnzo GC, Rosati A, Cutuli A, Gerli S, Burnelli L, Liotta L, et al. A prospective trial of two procedures for performing cesarean section [abstract]. American Journal of Obstetrics and Gynecology 2001;185(1):S124.

Falls 1958 {published data only}

Falls FH. Recent advances in obstetric and gynecologic surgery. Journal of the American Medical Association 1958;166:1409‐12.

Ferrari 2001 {published data only}

Ferrari AG, Frigerio LG, Candotti G, Buscaglia M, Petrone M, Taglioretti A, et al. Can Joel‐Cohen incision and single layer reconstruction reduce cesarean section morbidity?. International Journal of Gynecology & Obstetrics 2001;72:135‐43.

Franchi 1998 {published data only (unpublished sought but not used)}

Franchi M, Ghezzi F, Balestreri D, Beretta P, Maymon E, Miglierina M, et al. A randomized clinical trial of two surgical techniques for cesarean section. American Journal of Perinatology 1998;15(10):589‐94.
Franchi M, Ghezzi F, Balestreri D, Miglierina M, Zanaboni F, Donadello N, et al. A randomized clinical trial of two surgical techniques for cesarean section. American Journal of Obstetrics and Gynecology 1998;178:S31.

Gaucherand 2001 {published data only}

Gaucherand P, Bessai K, Sergeant P, Rudigoz RC. Towards simplified cesarean section? [Vers une simplification de l'operation cesarienne?]. Journal de Gynecologie, Obstetrique et Biologie de la Reproduction 2001;30:348‐52.

Hagen 1999 {published data only}

Hagen A, Schmid O, Runkel S, Weitzel H, Hopp H. A randomized trial of two surgical techniques for cesarean section. European Journal Obstetrics, Gynecology and Reproductive Biology 1999;86:S81.

Heimann 2000 {published data only (unpublished sought but not used)}

Heimann J, Hitschold T, Muller K, Berle P. Randomized trial of the modified Misgav‐Ladach and the conventional Pfannenstiel techniques for cesarean section [Modifizierte Misgav‐Ladach‐Technik der Sectio caesarea im Vergleich mit einer konventionellen Pfannenstiel‐technik‐ eine prospektiv‐randomisierte Studie an 240 Patientinnen eines Perinatalzentrums]. Geburtshilfe und Frauenheilkunde 2000;60:242‐50.

Hohlagschwandtner {published data only}

Hohlagschwandtner M, Ruecklinger E, Husslein P, Joura EA. Is the formation of a bladder flap at cesarean necessary?. A randomized trial. Obstetrics & Gynecology 2001;98:1089‐92.

Mahawerawat 2010 {published data only}

Mahawerawat S. Comparison of unintended uterine extension between cephalad‐caudad and transverse blunt expansion techniques for low transverse cesarean delivery. Thai Journal of Obstetrics and Gynaecology 2010;18:120‐5.

Meyer 1997 {published data only}

Meyer BA, Narain H, Morgan M, Jaekle RK. Comparison of electrocautery vs knife for elective cesarean in non‐labored patients. American Journal of Obstetrics and Gynecology 1997;176(1 Pt 2):S121.

Meyer 1998 {published data only}

Meyer BA, Narain H, Morgan M, Jaekle RK. Comparison of electrocautery vs knife for elective cesarean in labored patients. American Journal of Obstetrics and Gynecology 1998;178(1 Pt 2):S80.

Moreira 2002 {published data only (unpublished sought but not used)}

Moreira P, Moreau JC, Faye ME, Ka S, Kane Gueye SM, Faye EO, et al. Classic and Misgav‐Ladach cesarean: results of a comparative study [Comparaison de deux techniques de cesarienne: cesarienne classique versus cesarienne Misgav Ladach]. Journal de Gynecologie, Obstetrique et Biologie de la Reproduction 2002;31:572‐6.

Oguz 1998 {published data only}

Oguz S, Sener B, Ozcan S, Akyol D, Gokmen O. Nonfreeing of the lower leaf of the rectus sheath at caesarean section: a randomized controlled trial. Australian and New Zealand Journal of Obstetrics and Gynaecology 1998;38(3):317‐8.

Redlich 2001 {published data only}

Redlich A, Koppe I. The "gentle caesarean section" ‐ an alternative to the classical way of section. A prospective comparison between the classical technique and the method of Misgav Ladach ["Die sanfte Sectio" ‐ Eine Alternative zur klassischen Sectiotechnik. Prospektiver Vergleich der klassischen Technik mit der Misgav‐Ladach‐Methode]. Zentralblatt fur Gynakologie 2001;123:638‐43.

Wallin 1999 {published and unpublished data}

Wallin G, Fall O. Modified Joel‐Cohen technique for caesarean delivery. British Journal of Obstetrics and Gynaecology 1999;106:221‐6.
Wallin G, Fall O. Modified Joel‐Cohen technique for caesarean section. A prospective randomised trial. Acta Obstetricia et Gynecologica Scandinavica 1997;76(167 Suppl):24.

Xavier 1999 {published data only}

Xavier P, Ayres‐de‐Campos D, Reynolds A, Guimaraes M, Santos C, Patricio B. A randomised trial of the misgav‐ladach versus the classical technique for the caesarean section: preliminary results [abstract]. European Journal Obstetrics, Gynecology and Reproductive Biology 1999;86:S28‐S29.

CORONIS 2007 {published data only}

Juszczak E, Farrell B. The CORONIS Trial: international study of caesarean section surgical techniques. Trials 2011;112(Suppl 1):A103.
The CORONIS Trial Collaborative Group. The CORONIS trial. International study of caesarean section surgical techniques: a randomised fractional, factorial trial. BMC Pregnancy and Childbirth 2007;7:24.

Alderdice 2003

Alderdice F, McKenna D, Dornan J. Techniques and materials for skin closure in caesarean section. Cochrane Database of Systematic Reviews 2003, Issue 2. [DOI: 10.1002/14651858.CD003577]

Anderson 2004

Anderson ER, Gates S. Techniques and materials for closure of the abdominal wall in caesarean section. Cochrane Database of Systematic Reviews 2004, Issue 4. [DOI: 10.1002/14651858.CD004663.pub2]

Finan 1991

Finan MA, Mastrogiannis DS, Spellacy WN. The Allis test for easy cesarean delivery. American Journal of Obstetrics and Gynecology 1991;164:772‐5.

Higgins 2005

Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions 4.2.5 [updated May 2005}. In: The Cochrane Library, Issue 2, 2005. Chichester, UK: John Wiley & Sons, Ltd.

Higgins 2011

Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane‐handbook.org.

Holmgren 1999

Holmgren G, Sjoholm L, Stark M. The misgav ladach method for cesarean section: method description. Acta Obstetricia et Gynecologica Scandinavica 1999;78:615‐21.

Joel‐Cohen 1977

Joel‐Cohen S. Abdominal and Vaginal Hysterectomy. 2nd Edition. Philadelphia: JB Lippincott, 1977:18‐23.

Jokhan‐Jacob 2004

Jacob‐Jokhan D, Hofmeyr GJ. Extra‐abdominal versus intra‐abdominal repair of the uterine incision at caesarean section. Cochrane Database of Systematic Reviews 2004, Issue 4. [DOI: 10.1002/14651858.CD000085.pub2]

Kendall 1991

Kendall SW, Brennan TG, Guillou PJ. Suture length to wound length ratio and the integrity of midline and lateral paramedian incisions. British Journal of Surgery 1991;78:705‐7.

Kumar 1995

Kumar S, Dufresne RM, Van Schoor T. Human strength profile in flexion and extension. Spine 1995;20:160‐8.

Mouchel 1981

Mouchel J. Incision transversale transrectale en pratique gynecologique et obstetricale. La Nouvelle Press Medicale 1981;10:413‐5.

Myerscough 1982

Myerscough PR. Caesarean section: sterilization: hysterectomy. Munro Kerr's Operative Obstetrics. 10th Edition. London: Bailliere Tindall, 1982:295‐319.

O'Grady 1995

O'Grady JP, Veronikis DK, Chervenak FA, McCullough LB, Kanaan CM, Tilson JL. Cesarean delivery. In: O'Grady JP, Gimovsky ML editor(s). Operative Obstetrics. Baltimore: Williams & Wilkins, 1995:239‐87.

RevMan 2003 [Computer program]

The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 4.2 for Windows. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2003.

RevMan 2011 [Computer program]

The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.1. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2011.

Sreenivasan 2006

Sreenivasan KA. [Caesarean under local anaesthesia: a study of 1543 cases]. Conference Proceedings: 49th All India Congress of Obstetrics & Gynaecology; 2006; Kochi, Kerala. 2006:168. [IP‐9‐2‐0200‐2‐OBST]

WHO 2000

WHO/UNFPA/UNICEF/World Bank. Managing complications in pregnancy and childbirth: a guide for midwives and doctors. WHO/UNFPA/UNICEF/World Bank; 2000. Report No.:WHO/RHR/00.7.

Wood 1999

Wood RM, Simon H, Oz AU. Pelosi‐type vs traditional cesarean delivery. A prospective comparision. Journal of Reproductive Medicine 1999;44:788‐95.

Referencias de otras versiones publicadas de esta revisión

Mathai 2006

Mathai M, Hofmeyr GJ. Abdominal surgical incisions for caesarean section. Cochrane Database of Systematic Reviews 2006, Issue 4. [DOI: 10.1002/14651858.CD004453]

Mathai 2007

Mathai M, Hofmeyr GJ. Abdominal surgical incisions for caesarean section. Cochrane Database of Systematic Reviews 2007, Issue 1. [DOI: 10.1002/14651858.CD004453.pub2]

Characteristics of studies

Characteristics of included studies [ordered by study ID]

Berthet 1989

Methods

Randomisation to Mouchel incision or Pfannenstiel incision. Method of randomisation unclear.

Participants

58 women undergoing caesarean section by Mouchel or Pfannenstiel incision. The study also included 61 women undergoing gynaecological surgery in Grenoble, France.

Interventions

Mouchel (muscle‐cutting) incision (n = 28) versus Pfannenstiel incision (n = 30).

Outcomes

Extraction time.
Apgar scores.
Umbilical cord pH.

Notes

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Unclear risk

Insufficient information.

Allocation concealment (selection bias)

Unclear risk

Insufficient information.

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

Insufficient information.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Potential risk of bias in assessment of extraction time and Apgar scores. intraoperative maternal variables studied. Cord pH estimated for all babies. Postoperative maternal assessment by single observer unaware of allocation.

Incomplete outcome data (attrition bias)
All outcomes

Unclear risk

Insufficient information.

Selective reporting (reporting bias)

Unclear risk

Insufficient information.

Other bias

Unclear risk

Insufficient information.

Franchi 2002

Methods

Multicentre study. Sealed envelopes containing computer‐generated random codes.

Participants

Women over 18 years, singleton pregnancy with indication for caesarean delivery in Varese, Italy and Berne, Switzerland. Exclusion criteria were: gestation less than 32 weeks, previous myomectomy, previous longitudinal abdominal incision, previous caesarean section prior to 32 weeks, 2 or more caesarean sections, maternal diseases requiring long‐term medical treatment. 2 women in Joel‐Cohen group were excluded after randomisation because they required caesarean hysterectomy.

Interventions

Joel‐Cohen incision (n = 154) versus Pfannenstiel incision (n = 158) for laparotomic access.

Outcomes

Extraction time defined as interval from skin incision to the clamping of the umbilical cord.
Total operative time defined as the time from skin incision to the end of the skin closure.
Postoperative morbidity defined when at least 1 of the following conditions occurred: wound infection grade 2‐5, endometritis, sepsis, requirement of blood transfusion, febrile morbidity, puerperal infection, urinary tract infection, and requirement of a re‐laparotomy.
Neurodevelopmental assessment of infant at 6 months of age by single neonatologist.

Notes

Abdominal wound infection was graded with a 6‐grade score. Febrile morbidity was defined as temperature elevation to 38 deg C on 2 occasions 4 h apart, excluding the first 24 h and in the absence of known operative or non‐operative site infection. Puerperal endometritis was defined as postpartum temperature elevation to 38 deg C on 2 occasions 4 h apart with uterine tenderness, foul‐smelling lochia, and no other apparent sources of fever.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Computer‐generated randomisation.

Allocation concealment (selection bias)

Unclear risk

Envelopes used but unclear if sequentially numbered, opaque and sealed.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Since surgical team was aware of allocated intervention, assessment of intraoperative variables (secondary outcomes) may have been subject to bias.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Unclear if women and health workers providing postoperative newborn care and assessments were adequately blinded.

Incomplete outcome data (attrition bias)
All outcomes

Low risk

Data from 1 woman in each group excluded after randomisation because of caesarean hysterectomy.

Selective reporting (reporting bias)

Unclear risk

Insufficient information.

Other bias

Unclear risk

Insufficient information.

Giacalone 2002

Methods

Consecutively‐numbered, sealed envelopes containing allocation code.

Participants

Women (n = 120) more than 18 years old and at gestation more than 37 weeks undergoing elective or emergency caesarean delivery in Montpelier, France. Excluded were women with scarred abdominal wall, previous caesarean delivery, hernia, multifetal gestation, grand multiparity, diabetes mellitus, myopathy, corticosteroid therapy during pregnancy, on anticoagulants or having haemostatic disorder, having general anaesthesia. Mother was not asked to participate when neonate was at risk of transfer to neonatal unit. Postoperative questionnaires and outcome variables were available for 97 (87%). Postoperative isokinetic assessment was performed on 54 of these women only.

Interventions

Maylard (muscle‐cutting) incision (n = 43) versus Pfannenstiel incision (n = 54) for laparotomic access.

Outcomes

Intraoperative and postoperative morbidity.
Immediate and late postoperative pain.
Health‐related quality of life.
Evaluation of abdominal wall function by physical therapist.

Notes

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Random number table used.

Allocation concealment (selection bias)

Low risk

Consequently numbered, sealed envelopes.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Since surgical team was aware of allocated intervention, assessment of intraoperative variables may have been subject to bias.

Blinding of outcome assessment (detection bias)
All outcomes

Low risk

Women and health workers providing postoperative care and assessment were unaware of allocation.

Incomplete outcome data (attrition bias)
All outcomes

High risk

Postoperative questionnaires and outcome variables available for only 81% of women with fewer women in intervention arm.

Selective reporting (reporting bias)

Unclear risk

Insufficient information.

Other bias

Unclear risk

Insufficient information.

Mathai 2002

Methods

Sealed, consecutively‐numbered envelopes containing randomisation code. Block randomisation to 1 of 2 interventions.

Participants

Women (n = 105) with singleton pregnancies at longitudinal lie at term requiring cesarean delivery under spinal anaesthesia in Vellore, India. Excluded were those with multiple pregnancy, any previous abdominal surgery, conditions where midline or paramedian incisions were planned, and where spinal anaesthesia was contraindicated. Spinal anaesthesia was ineffective in 1 in each group. 2 women in Joel Cohen group (1 underwent caesarean hysterectomy; 1 had vaginal delivery prior to caesarean section).

Interventions

Joel‐Cohen incision (n = 51) versus Pfannenstiel incision (n = 50) for laparotomic access.

Outcomes

Analgesia on demand within the first 4 h after surgery.
Time between surgery and first dose of analgesic.
Time between skin incision and delivery of infant.
Time between skin incision and closure.
Estimated blood loss.
Time between surgery and intake of oral fluids.
Total dose of analgesics in first 24 h.
Febrile morbidity.
Haematocrit ‐ preoperative and postoperative.
Time from surgery to start of breastfeeding.
Duration of stay in special care nursery.
Duration of postoperative hospitalisation.

Notes

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Block randomisation.

Allocation concealment (selection bias)

Low risk

Sequentially numbered, opaque, sealed envelopes.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Since surgical team was aware of allocated intervention, assessment of intraoperative variables (secondary outcomes) may have been subject to bias.

Blinding of outcome assessment (detection bias)
All outcomes

Low risk

Women and health workers providing postoperative care were not aware of allocation.

Incomplete outcome data (attrition bias)
All outcomes

Low risk

4 exclusions after randomisation ‐ 1 in each group due to ineffective spinal analgesia; 1 in intervention group following caesarean hysterectomy for PPH; 1 in control group delivered vaginally before caesarean section.

Selective reporting (reporting bias)

Unclear risk

Insufficient information.

Other bias

Unclear risk

Insufficient information.

deg: degree
h: hour
PPH: postpartum haemorrhage

Characteristics of excluded studies [ordered by study ID]

Study

Reason for exclusion

Ansaloni 2001

Alternate allocation, not randomised.

Ayers 1987

Treatment allocation based on hospital number.

Ayres‐de‐Campos 2000

Not enough data provided in abstract for assessment.

Behrens 1997

Not enough data provided in abstract for assessment.

Bjorklund 2000

Comparison of abdominal incisions along with different combinations of other steps of surgery.

Dani 1998

Comparison of abdominal incisions along with different combinations of other steps of surgery.

Darj 1999

Comparison of abdominal incisions along with different combinations of other steps of surgery.

Decavalas 1997

Not enough data provided in abstract for assessment.

Direnzo 2001

Not enough data provided in abstract for assessment.

Falls 1958

Not a randomised controlled trial.

Ferrari 2001

Comparison of abdominal incisions along with different combinations of other steps of surgery.

Franchi 1998

Comparison of abdominal incisions along with different combinations of other steps of surgery.

Gaucherand 2001

Treatment allocation by year of birth.

Hagen 1999

Not enough data provided in abstract for assessment.

Heimann 2000

Comparison of abdominal incisions along with different combinations of other steps of surgery.

Hohlagschwandtner

Not a comparison of abdominal incisions.

Mahawerawat 2010

Not a comparison of abdominal incisions.

Meyer 1997

Not enough data provided in abstract for assessment.

Meyer 1998

Not enough data provided in abstract for assessment.

Moreira 2002

Comparison of abdominal incisions along with different combinations of other steps of surgery.

Oguz 1998

Not a comparison of abdominal incisions

Redlich 2001

Treatment allocation by first letter of surname.

Wallin 1999

Comparison of abdominal incisions along with different combinations of other steps of surgery.

Xavier 1999

Not enough data provided in abstract for assessment.

Characteristics of ongoing studies [ordered by study ID]

CORONIS 2007

Trial name or title

The Coronis Trial.

Methods

International multicentre study of caesarean section surgical techniques: a randomised fractional, factorial trial.

Participants

Women undergoing their first or second caesarean section through a transverse abdominal incision.

Interventions

Five comparisons using a 2 x 2 x 2 x 2 x 2 fractional factorial design:

  • Blunt versus sharp abdominal entry.

  • Exteriorisation of the uterus for repair versus intra‐abdominal repair.

  • Single versus double layer closure of the uterus.

  • Closure versus non‐closure of the peritoneum (pelvic and parietal).

  • Chromic catgut versus Polyglactin‐910 for uterine repair.

Outcomes

Primary outcome: death or maternal infectious morbidity (one or more of the following: antibiotic use for maternal febrile morbidity during postnatal hospital stay, antibiotic use for endometritis, wound infection or peritonitis) or further operative procedures; or blood transfusion.

Starting date

Not stated in reports.

Contact information

The CORONIS Trial Collaborative Group, Peter Brocklehurst: [email protected]

Notes

Data and analyses

Open in table viewer
Comparison 1. Joel‐Cohen versus Pfannenstiel incision

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Postoperative febrile morbidity Show forest plot

2

411

Risk Ratio (M‐H, Fixed, 95% CI)

0.35 [0.14, 0.87]

Analysis 1.1

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 1 Postoperative febrile morbidity.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 1 Postoperative febrile morbidity.

1.1 Joel‐Cohen versus Pfannenstiel incision

2

411

Risk Ratio (M‐H, Fixed, 95% CI)

0.35 [0.14, 0.87]

2 Postoperative analgesia on demand Show forest plot

1

101

Risk Ratio (M‐H, Fixed, 95% CI)

0.55 [0.40, 0.76]

Analysis 1.2

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 2 Postoperative analgesia on demand.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 2 Postoperative analgesia on demand.

3 Time between surgery and first dose of analgesic (hours) Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

0.80 [0.12, 1.48]

Analysis 1.3

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 3 Time between surgery and first dose of analgesic (hours).

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 3 Time between surgery and first dose of analgesic (hours).

4 Total dose of analgesics in 24 hours Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐0.89 [‐1.19, ‐0.59]

Analysis 1.4

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 4 Total dose of analgesics in 24 hours.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 4 Total dose of analgesics in 24 hours.

5 Number of analgesic injections required

0

0

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

6 Duration of analgesics (hours)

0

0

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

7 Number of analgesic doses required

0

0

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

8 Estimated blood loss (mL) Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐58.0 [‐108.51, ‐7.49]

Analysis 1.8

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 8 Estimated blood loss (mL).

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 8 Estimated blood loss (mL).

9 Change in pre‐ and postoperative haemoglobin levels (g)

0

0

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

10 Blood transfusion Show forest plot

1

310

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

Analysis 1.10

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 10 Blood transfusion.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 10 Blood transfusion.

11 Wound infection as defined by trial authors Show forest plot

1

310

Risk Ratio (M‐H, Random, 95% CI)

1.56 [0.45, 5.42]

Analysis 1.11

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 11 Wound infection as defined by trial authors.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 11 Wound infection as defined by trial authors.

12 Wound haematoma

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

13 Postoperative pain absent on day 1

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

14 Postoperative pain absent on day 2

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

15 "Significant" postoperative pain by visual analogue score

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

16 Time (hours) from surgery to start of breastfeeding Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐5.5 [‐13.62, 2.62]

Analysis 1.16

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 16 Time (hours) from surgery to start of breastfeeding.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 16 Time (hours) from surgery to start of breastfeeding.

17 Total operative time (minutes) Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐11.40 [‐16.55, ‐6.25]

Analysis 1.17

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 17 Total operative time (minutes).

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 17 Total operative time (minutes).

18 Need for re‐laparotomy Show forest plot

1

310

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

Analysis 1.18

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 18 Need for re‐laparotomy.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 18 Need for re‐laparotomy.

19 Long‐term "significant" wound pain assessed by visual analogue score

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

20 Not satisfied with wound

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

21 Delivery time (minutes) Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐1.90 [‐2.53, ‐1.27]

Analysis 1.21

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 21 Delivery time (minutes).

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 21 Delivery time (minutes).

22 5‐minute Apgar score less than 7

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

23 Admissions to special care baby unit ‐ all types Show forest plot

1

310

Risk Ratio (M‐H, Fixed, 95% CI)

1.19 [0.44, 3.20]

Analysis 1.23

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 23 Admissions to special care baby unit ‐ all types.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 23 Admissions to special care baby unit ‐ all types.

24 Admission to special care baby unit ‐ emergency caesarean section Show forest plot

1

98

Risk Ratio (M‐H, Fixed, 95% CI)

1.45 [0.54, 3.86]

Analysis 1.24

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 24 Admission to special care baby unit ‐ emergency caesarean section.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 24 Admission to special care baby unit ‐ emergency caesarean section.

25 Postoperative hospital stay for mother (days) Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐1.5 [‐2.16, ‐0.84]

Analysis 1.25

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 25 Postoperative hospital stay for mother (days).

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 25 Postoperative hospital stay for mother (days).

26 Stay in special care nursery (days) Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐0.46 [‐0.95, 0.03]

Analysis 1.26

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 26 Stay in special care nursery (days).

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 26 Stay in special care nursery (days).

Open in table viewer
Comparison 2. Muscle‐cutting/Maylard versus Pfannenstiel incision

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Postoperative febrile morbidity Show forest plot

1

97

Risk Ratio (M‐H, Fixed, 95% CI)

1.26 [0.08, 19.50]

Analysis 2.1

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 1 Postoperative febrile morbidity.

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 1 Postoperative febrile morbidity.

2 Blood transfusion Show forest plot

1

97

Risk Ratio (M‐H, Fixed, 95% CI)

0.42 [0.02, 9.98]

Analysis 2.2

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 2 Blood transfusion.

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 2 Blood transfusion.

3 Wound infection as defined by trial authors Show forest plot

1

97

Risk Ratio (M‐H, Fixed, 95% CI)

1.26 [0.27, 5.91]

Analysis 2.3

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 3 Wound infection as defined by trial authors.

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 3 Wound infection as defined by trial authors.

4 Long‐term complication ‐ physical test at 3 months (Janda's test) Show forest plot

1

54

Mean Difference (IV, Fixed, 95% CI)

0.10 [‐0.73, 0.93]

Analysis 2.4

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 4 Long‐term complication ‐ physical test at 3 months (Janda's test).

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 4 Long‐term complication ‐ physical test at 3 months (Janda's test).

5 Postoperative hospital stay for mother (days) Show forest plot

1

97

Mean Difference (IV, Fixed, 95% CI)

0.40 [‐0.34, 1.14]

Analysis 2.5

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 5 Postoperative hospital stay for mother (days).

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 5 Postoperative hospital stay for mother (days).

'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
Figuras y tablas -
Figure 1

'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.

'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.
Figuras y tablas -
Figure 2

'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 1 Postoperative febrile morbidity.
Figuras y tablas -
Analysis 1.1

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 1 Postoperative febrile morbidity.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 2 Postoperative analgesia on demand.
Figuras y tablas -
Analysis 1.2

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 2 Postoperative analgesia on demand.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 3 Time between surgery and first dose of analgesic (hours).
Figuras y tablas -
Analysis 1.3

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 3 Time between surgery and first dose of analgesic (hours).

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 4 Total dose of analgesics in 24 hours.
Figuras y tablas -
Analysis 1.4

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 4 Total dose of analgesics in 24 hours.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 8 Estimated blood loss (mL).
Figuras y tablas -
Analysis 1.8

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 8 Estimated blood loss (mL).

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 10 Blood transfusion.
Figuras y tablas -
Analysis 1.10

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 10 Blood transfusion.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 11 Wound infection as defined by trial authors.
Figuras y tablas -
Analysis 1.11

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 11 Wound infection as defined by trial authors.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 16 Time (hours) from surgery to start of breastfeeding.
Figuras y tablas -
Analysis 1.16

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 16 Time (hours) from surgery to start of breastfeeding.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 17 Total operative time (minutes).
Figuras y tablas -
Analysis 1.17

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 17 Total operative time (minutes).

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 18 Need for re‐laparotomy.
Figuras y tablas -
Analysis 1.18

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 18 Need for re‐laparotomy.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 21 Delivery time (minutes).
Figuras y tablas -
Analysis 1.21

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 21 Delivery time (minutes).

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 23 Admissions to special care baby unit ‐ all types.
Figuras y tablas -
Analysis 1.23

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 23 Admissions to special care baby unit ‐ all types.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 24 Admission to special care baby unit ‐ emergency caesarean section.
Figuras y tablas -
Analysis 1.24

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 24 Admission to special care baby unit ‐ emergency caesarean section.

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 25 Postoperative hospital stay for mother (days).
Figuras y tablas -
Analysis 1.25

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 25 Postoperative hospital stay for mother (days).

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 26 Stay in special care nursery (days).
Figuras y tablas -
Analysis 1.26

Comparison 1 Joel‐Cohen versus Pfannenstiel incision, Outcome 26 Stay in special care nursery (days).

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 1 Postoperative febrile morbidity.
Figuras y tablas -
Analysis 2.1

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 1 Postoperative febrile morbidity.

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 2 Blood transfusion.
Figuras y tablas -
Analysis 2.2

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 2 Blood transfusion.

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 3 Wound infection as defined by trial authors.
Figuras y tablas -
Analysis 2.3

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 3 Wound infection as defined by trial authors.

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 4 Long‐term complication ‐ physical test at 3 months (Janda's test).
Figuras y tablas -
Analysis 2.4

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 4 Long‐term complication ‐ physical test at 3 months (Janda's test).

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 5 Postoperative hospital stay for mother (days).
Figuras y tablas -
Analysis 2.5

Comparison 2 Muscle‐cutting/Maylard versus Pfannenstiel incision, Outcome 5 Postoperative hospital stay for mother (days).

Comparison 1. Joel‐Cohen versus Pfannenstiel incision

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Postoperative febrile morbidity Show forest plot

2

411

Risk Ratio (M‐H, Fixed, 95% CI)

0.35 [0.14, 0.87]

1.1 Joel‐Cohen versus Pfannenstiel incision

2

411

Risk Ratio (M‐H, Fixed, 95% CI)

0.35 [0.14, 0.87]

2 Postoperative analgesia on demand Show forest plot

1

101

Risk Ratio (M‐H, Fixed, 95% CI)

0.55 [0.40, 0.76]

3 Time between surgery and first dose of analgesic (hours) Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

0.80 [0.12, 1.48]

4 Total dose of analgesics in 24 hours Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐0.89 [‐1.19, ‐0.59]

5 Number of analgesic injections required

0

0

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

6 Duration of analgesics (hours)

0

0

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

7 Number of analgesic doses required

0

0

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

8 Estimated blood loss (mL) Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐58.0 [‐108.51, ‐7.49]

9 Change in pre‐ and postoperative haemoglobin levels (g)

0

0

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

10 Blood transfusion Show forest plot

1

310

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

11 Wound infection as defined by trial authors Show forest plot

1

310

Risk Ratio (M‐H, Random, 95% CI)

1.56 [0.45, 5.42]

12 Wound haematoma

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

13 Postoperative pain absent on day 1

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

14 Postoperative pain absent on day 2

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

15 "Significant" postoperative pain by visual analogue score

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

16 Time (hours) from surgery to start of breastfeeding Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐5.5 [‐13.62, 2.62]

17 Total operative time (minutes) Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐11.40 [‐16.55, ‐6.25]

18 Need for re‐laparotomy Show forest plot

1

310

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

19 Long‐term "significant" wound pain assessed by visual analogue score

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

20 Not satisfied with wound

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

21 Delivery time (minutes) Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐1.90 [‐2.53, ‐1.27]

22 5‐minute Apgar score less than 7

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

23 Admissions to special care baby unit ‐ all types Show forest plot

1

310

Risk Ratio (M‐H, Fixed, 95% CI)

1.19 [0.44, 3.20]

24 Admission to special care baby unit ‐ emergency caesarean section Show forest plot

1

98

Risk Ratio (M‐H, Fixed, 95% CI)

1.45 [0.54, 3.86]

25 Postoperative hospital stay for mother (days) Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐1.5 [‐2.16, ‐0.84]

26 Stay in special care nursery (days) Show forest plot

1

101

Mean Difference (IV, Fixed, 95% CI)

‐0.46 [‐0.95, 0.03]

Figuras y tablas -
Comparison 1. Joel‐Cohen versus Pfannenstiel incision
Comparison 2. Muscle‐cutting/Maylard versus Pfannenstiel incision

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Postoperative febrile morbidity Show forest plot

1

97

Risk Ratio (M‐H, Fixed, 95% CI)

1.26 [0.08, 19.50]

2 Blood transfusion Show forest plot

1

97

Risk Ratio (M‐H, Fixed, 95% CI)

0.42 [0.02, 9.98]

3 Wound infection as defined by trial authors Show forest plot

1

97

Risk Ratio (M‐H, Fixed, 95% CI)

1.26 [0.27, 5.91]

4 Long‐term complication ‐ physical test at 3 months (Janda's test) Show forest plot

1

54

Mean Difference (IV, Fixed, 95% CI)

0.10 [‐0.73, 0.93]

5 Postoperative hospital stay for mother (days) Show forest plot

1

97

Mean Difference (IV, Fixed, 95% CI)

0.40 [‐0.34, 1.14]

Figuras y tablas -
Comparison 2. Muscle‐cutting/Maylard versus Pfannenstiel incision