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Antifibrinolytic agent tranexamic acid for nasal haemorrhage (epistaxis)

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Appendices

Appendix 1. Search strategies

CENTRAL

MEDLINE

EMBASE

#1 EPISTAXIS explode all trees (MeSH) 
#2 epistax*  
#3 nosebleed* 
#4 rhinorrhag*OR rhinorrhaeg* 
#5 #1 OR #2 OR #3 OR #4 
#6 NOSE explode all trees (MeSH)
#7 (nose OR nasal)
#8 #6 OR #7
#9 HEMORRHAGE explode all trees (MeSH)
#10 hemorrhag*OR haemorrhag*
#11 bleed*OR bloodloss*
#12 blood NEAR loss*
#13 #9 OR #10 OR #11 OR #12
#14 #8 AND #13
#15 #5 OR #14
#16 TRANEXAMIC ACID exp all trees (MeSH)
#17 ANTIFIBRINOLYTIC AGENTS single term (MeSH)
#18 tranexamic OR amca OR AMCHA OR amchafibrin OR amikapron OR aminomethylcyclohexanecarbonic OR aminomethylcyclohexane carbonic OR aminomethylcyclohexanocarbonic
#19 methylcyclohexane carboxylate OR aminomethylcyclohexanecarboxylicOR aminomethyl cyclohexane carboxylic OR aminomethyl cyclohexanecarboxylic OR aminomethylcyclohexane carboxylic OR aminomethylcyclohexanecarboxylic OR aminomethylcyclohexanocarboxylic OR aminomethylcyclohexanoic OR amstat OR anvitoff
#20 cyclocapron OR cyclokapron OR cyklocapron OR cyklokapron OR exacyl OR frenolyse OR hexacapron OR hexakapron OR tranex OR tranexanic OR trans achma OR transamin OR transaminomethylcyclohexane carboxylic OR transexamic OR ugurol
#21 #16 OR #17 OR #18 OR #19 OR #20

1. EPISTAXIS#.DE.
2. EPISTAX$2.TI,AB.  
3. NOSEBLEED$4.TI,AB.
4. (RHINORRHAG$5 OR RHINORRHAEG$5).TI,AB.
5. 1 OR 2 OR 3 OR 4
6. NOSE#.DE.
7. (NOSE OR NASAL).TI,AB. 
8. 6 OR 7
9. HEMORRHAGE#.DE. 
10. (HEMORRHAG$3 OR HAEMORRHAG$3).TI,AB.
11. (BLEED$4 OR BLOODLOSS$2).TI,AB.
12. BLOOD NEAR LOSS$2.TI,AB.
13. 9 OR 10 OR 11 OR 12
14. 8 AND 13
15. 5 OR 14
16. TRANEXAMIC‐ACID.DE.
17. ANTIFIBRINOLYTIC‐AGENTS.DE.
18. (tranexamic OR amca OR AMCHA OR amchafibrin OR amikapron OR  aminomethylcyclohexanecarbonic OR aminomethylcyclohexane ADJ carbonic OR aminomethylcyclohexanocarbonic).TI,AB.
19. (methylcyclohexane ADJ carboxylate OR aminomethylcyclohexanecarboxylic OR aminomethyl ADJ cyclohexane ADJ carboxylic OR aminomethyl ADJ cyclohexanecarboxylic OR aminomethylcyclohexane ADJ carboxylic OR aminomethylcyclohexanecarboxylic OR aminomethylcyclohexanocarboxylic OR aminomethylcyclohexanoic OR amstat OR anvitoff OR cl ADJ '65336').TI,AB.
20. (cl65336 OR cyclocapron OR cyclokapron OR cyklocapron OR cyklokapron OR exacyl OR frenolyse OR hexacapron OR hexakapron OR tranex OR tranexanic OR trans ADJ achma OR transamin OR transaminomethylcyclohexane ADJ carboxylic OR transexamic OR ugurol).TI,AB.
21. 1197‐18‐8.RN.
22. 16 OR 17 OR 18 OR 19 OR 20 OR 21
23. 15 AND 22

1. EPISTAXIS#.DE.
2. EPISTAX$2.TI,AB.
3. NOSEBLEED$4.TI,AB. 
4. (RHINORRHAG$5 OR RHINORRHAEG$5).TI,AB.
5. 1 OR 2 OR 3 OR 4
6. NOSE#.DE. 
7. (NOSE OR NASAL).TI,AB.
8. 6 OR 7
9. BLEEDING#.DE.
10. (HEMORRHAG$3 OR HAEMORRHAG$3).TI,AB. 
11. (BLEED$4 OR BLOODLOSS$2).TI,AB.
12. BLOOD NEAR LOSS$2.TI,AB.
13. 9 OR 10 OR 11 OR 12
14. 8 AND 13
15. 5 OR 14
16. TRANEXAMIC‐ACID.DE.
17. ANTIFIBRINOLYTIC‐AGENT.DE.
18. (tranexamic OR amca OR AMCHA OR amchafibrin OR amikapron OR aminomethylcyclohexanecarbonic OR aminomethylcyclohexane ADJ carbonic OR aminomethylcyclohexanocarbonic).TI,AB.
19. (methylcyclohexane ADJ carboxylate OR aminomethylcyclohexanecarboxylic OR aminomethyl ADJ cyclohexane ADJ carboxylic OR aminomethyl ADJ cyclohexanecarboxylic OR aminomethylcyclohexane ADJ carboxylic OR aminomethylcyclohexanecarboxylic OR aminomethylcyclohexanocarboxylic OR aminomethylcyclohexanoic OR amstat OR anvitoff OR cl ADJ '65336').TI,AB.
20. (cl65336 OR cyclocapron OR cyclokapron OR cyklocapron OR cyklokapron OR exacyl OR frenolyse OR hexacapron OR hexakapron OR tranex OR tranexanic OR trans ADJ achma OR transamin OR transaminomethylcyclohexane ADJ carboxylic OR transexamic OR ugurol).TI,AB.
21. 197‐18‐8.RN.
22. 16 OR 17 OR 18 OR 19 OR 20 OR 21
23. 15 AND 22