Single dose oral naproxen and naproxen sodium for acute postoperative pain

Scolaris Content Display Scolaris Content Display

Ir a:

Analysis 1.1

Comparison 1 No. Patients with at least 50% pain relief, Outcome 1 Naproxen sodium 550 mg.

Analysis 1.2

Comparison 1 No. Patients with at least 50% pain relief, Outcome 2 Naproxen/naproxen sodium 400/440 mg.

Analysis 1.3

Comparison 1 No. Patients with at least 50% pain relief, Outcome 3 Naproxen/naproxen sodium 200/220 mg.

Analysis 2.1

Comparison 2 Adverse events, Outcome 1 Naproxen sodium 550 mg.

Analysis 2.2

Comparison 2 Adverse events, Outcome 2 Naproxen/naproxen sodium 400/440 mg.

Analysis 2.3

Comparison 2 Adverse events, Outcome 3 Naproxen/naproxen sodium 200/220 mg.

Comparison 1. No. Patients with at least 50% pain relief

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Naproxen sodium 550 mg Show forest plot	6	500	Risk Ratio (M‐H, Fixed, 95% CI)	4.18 [2.93, 5.97]

2 Naproxen/naproxen sodium 400/440 mg Show forest plot	3	334	Risk Ratio (M‐H, Fixed, 95% CI)	4.80 [2.75, 8.38]

3 Naproxen/naproxen sodium 200/220 mg Show forest plot	2	202	Risk Ratio (M‐H, Fixed, 95% CI)	2.87 [1.60, 5.15]

Comparison 1. No. Patients with at least 50% pain relief

Comparison 2. Adverse events

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Naproxen sodium 550 mg Show forest plot	5	392	Risk Ratio (M‐H, Fixed, 95% CI)	0.89 [0.63, 1.25]

2 Naproxen/naproxen sodium 400/440 mg Show forest plot	2	257	Risk Ratio (M‐H, Fixed, 95% CI)	1.32 [0.78, 2.24]

3 Naproxen/naproxen sodium 200/220 mg Show forest plot	1	122	Risk Ratio (M‐H, Fixed, 95% CI)	2.21 [0.90, 5.43]

Comparison 2. Adverse events