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Comparison 1 Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 1 Need for unscheduled intravenous infusion.
Figuras y tablas -
Analysis 1.1

Comparison 1 Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 1 Need for unscheduled intravenous infusion.

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Comparison 1 Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 2 Biochemical hyponatremia (serum sodium < 130 mmol/L).
Figuras y tablas -
Analysis 1.2

Comparison 1 Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 2 Biochemical hyponatremia (serum sodium < 130 mmol/L).

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Comparison 1 Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 3 Severe biochemical hyponatremia (serum sodium < 125 mmol/L).
Figuras y tablas -
Analysis 1.3

Comparison 1 Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 3 Severe biochemical hyponatremia (serum sodium < 125 mmol/L).

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Comparison 1 Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 4 Duration of diarrhea.
Figuras y tablas -
Analysis 1.4

Comparison 1 Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 4 Duration of diarrhea.

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Comparison 1 Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 5 Stool volume in first 24 hours after admission or randomization.
Figuras y tablas -
Analysis 1.5

Comparison 1 Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 5 Stool volume in first 24 hours after admission or randomization.

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Comparison 1 Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 6 Vomiting during rehydration.
Figuras y tablas -
Analysis 1.6

Comparison 1 Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 6 Vomiting during rehydration.

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Comparison 2 Reduced osmolarity (rice‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 1 Biochemical hyponatremia (serum sodium < 130 mmol/L).
Figuras y tablas -
Analysis 2.1

Comparison 2 Reduced osmolarity (rice‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 1 Biochemical hyponatremia (serum sodium < 130 mmol/L).

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Comparison 2 Reduced osmolarity (rice‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 2 Severe biochemical hyponatremia (serum sodium < 125 mmol/L).
Figuras y tablas -
Analysis 2.2

Comparison 2 Reduced osmolarity (rice‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 2 Severe biochemical hyponatremia (serum sodium < 125 mmol/L).

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Comparison 2 Reduced osmolarity (rice‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 3 Duration of diarrhea.
Figuras y tablas -
Analysis 2.3

Comparison 2 Reduced osmolarity (rice‐based) oral rehydration solution (ORS) versus standard ORS, Outcome 3 Duration of diarrhea.

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Comparison 1. Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Need for unscheduled intravenous infusion Show forest plot

5

616

Risk Ratio (M‐H, Fixed, 95% CI)

0.86 [0.66, 1.12]

1.1 Children

2

93

Risk Ratio (M‐H, Fixed, 95% CI)

0.57 [0.29, 1.11]

1.2 Adults

3

523

Risk Ratio (M‐H, Fixed, 95% CI)

0.93 [0.70, 1.24]

2 Biochemical hyponatremia (serum sodium < 130 mmol/L) Show forest plot

4

465

Risk Ratio (M‐H, Fixed, 95% CI)

1.67 [1.09, 2.57]

2.1 Children

1

39

Risk Ratio (M‐H, Fixed, 95% CI)

1.58 [0.53, 4.74]

2.2 Adults

3

426

Risk Ratio (M‐H, Fixed, 95% CI)

1.69 [1.06, 2.69]

3 Severe biochemical hyponatremia (serum sodium < 125 mmol/L) Show forest plot

4

465

Risk Ratio (M‐H, Fixed, 95% CI)

1.58 [0.62, 4.04]

3.1 Children

1

39

Risk Ratio (M‐H, Fixed, 95% CI)

0.35 [0.02, 8.10]

3.2 Adults

3

426

Risk Ratio (M‐H, Fixed, 95% CI)

1.91 [0.68, 5.31]

4 Duration of diarrhea Show forest plot

7

718

Mean Difference (IV, Random, 95% CI)

‐1.08 [‐4.58, 2.41]

4.1 Children

3

132

Mean Difference (IV, Random, 95% CI)

1.42 [0.29, 2.55]

4.2 Adults

4

586

Mean Difference (IV, Random, 95% CI)

‐2.54 [‐8.78, 3.70]

5 Stool volume in first 24 hours after admission or randomization Show forest plot

4

581

Std. Mean Difference (IV, Random, 95% CI)

‐0.13 [‐0.43, 0.17]

5.1 Children

1

58

Std. Mean Difference (IV, Random, 95% CI)

0.03 [‐0.49, 0.55]

5.2 Adults

3

523

Std. Mean Difference (IV, Random, 95% CI)

‐0.18 [‐0.57, 0.20]

6 Vomiting during rehydration Show forest plot

2

363

Risk Ratio (M‐H, Fixed, 95% CI)

1.14 [0.92, 1.40]

6.1 Children

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

6.2 Adults

2

363

Risk Ratio (M‐H, Fixed, 95% CI)

1.14 [0.92, 1.40]
Figuras y tablas -
Comparison 1. Reduced osmolarity (glucose‐based) oral rehydration solution (ORS) versus standard ORS
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Comparison 2. Reduced osmolarity (rice‐based) oral rehydration solution (ORS) versus standard ORS

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Biochemical hyponatremia (serum sodium < 130 mmol/L) Show forest plot

2

102

Risk Ratio (M‐H, Fixed, 95% CI)

0.66 [0.26, 1.69]

1.1 Children

1

39

Risk Ratio (M‐H, Fixed, 95% CI)

1.05 [0.31, 3.62]

1.2 Adults

1

63

Risk Ratio (M‐H, Fixed, 95% CI)

0.36 [0.08, 1.74]

2 Severe biochemical hyponatremia (serum sodium < 125 mmol/L) Show forest plot

2

102

Risk Ratio (M‐H, Fixed, 95% CI)

0.35 [0.02, 8.10]

2.1 Children

1

39

Risk Ratio (M‐H, Fixed, 95% CI)

0.35 [0.02, 8.10]

2.2 Adults

1

63

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

3 Duration of diarrhea Show forest plot

2

102

Mean Difference (IV, Fixed, 95% CI)

‐16.85 [‐21.22, ‐12.48]

3.1 Children

1

39

Mean Difference (IV, Fixed, 95% CI)

‐9.13 [‐21.27, 3.01]

3.2 Adults

1

63

Mean Difference (IV, Fixed, 95% CI)

‐18.0 [‐22.68, ‐13.32]
Figuras y tablas -
Comparison 2. Reduced osmolarity (rice‐based) oral rehydration solution (ORS) versus standard ORS
Ir a la tabla de la revisión