Optimal timing for intravenous administration set replacement

Donna Gillies; Margaret M Wallen; Anne L Morrison; Karen Rankin; Sue A Nagy; Elizabeth O'Riordan

doi:10.1002/14651858.CD003588.pub2

Scolaris Content Display Scolaris Content Display

Contenido relacionado

Ir a:

Revisiones y protocolos relacionados
Guías
Temas

Revisiones y protocolos relacionados

Topics

Temas

Analysis 1.1

Comparison 1 Primary analysis: less versus more frequent, Outcome 1 Infusate colonization.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 1.2

Comparison 1 Primary analysis: less versus more frequent, Outcome 2 Infusate‐related BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 1.3

Comparison 1 Primary analysis: less versus more frequent, Outcome 3 Catheter colonization.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 1.4

Comparison 1 Primary analysis: less versus more frequent, Outcome 4 Catheter‐related BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 1.5

Comparison 1 Primary analysis: less versus more frequent, Outcome 5 All‐cause BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 1.6

Comparison 1 Primary analysis: less versus more frequent, Outcome 6 Mortality.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 1.7

Comparison 1 Primary analysis: less versus more frequent, Outcome 7 BSI‐related deaths.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 2.1

Comparison 2 Subgroup analysis: 1. site; less versus more frequent, Outcome 1 Infusate colonization.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 2.2

Comparison 2 Subgroup analysis: 1. site; less versus more frequent, Outcome 2 Infusate‐related BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 2.3

Comparison 2 Subgroup analysis: 1. site; less versus more frequent, Outcome 3 Catheter colonization.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 2.4

Comparison 2 Subgroup analysis: 1. site; less versus more frequent, Outcome 4 Catheter‐related BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 3.1

Comparison 3 Subgroup analysis: 2. infusate; less versus more frequent, Outcome 1 Infusate colonization.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 3.2

Comparison 3 Subgroup analysis: 2. infusate; less versus more frequent, Outcome 2 Infusate‐related BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 3.3

Comparison 3 Subgroup analysis: 2. infusate; less versus more frequent, Outcome 3 Catheter colonization.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 3.4

Comparison 3 Subgroup analysis: 2. infusate; less versus more frequent, Outcome 4 Catheter‐related BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 3.5

Comparison 3 Subgroup analysis: 2. infusate; less versus more frequent, Outcome 5 All‐cause BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 4.1

Comparison 4 Subgroup analysis: 3. age group; less versus more frequent, Outcome 1 Infusate‐related BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 4.2

Comparison 4 Subgroup analysis: 3. age group; less versus more frequent, Outcome 2 All‐cause BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 5.1

Comparison 5 Sensitivity analysis: 1. study quality; less versus more frequent, Outcome 1 Catheter colonization.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 5.2

Comparison 5 Sensitivity analysis: 1. study quality; less versus more frequent, Outcome 2 Catheter‐related BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 5.3

Comparison 5 Sensitivity analysis: 1. study quality; less versus more frequent, Outcome 3 Mortality.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 6.1

Comparison 6 Sensitivity analysis: 2. intention to treat; less versus more frequent, Outcome 1 Infusate colonization.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 6.2

Comparison 6 Sensitivity analysis: 2. intention to treat; less versus more frequent, Outcome 2 Infusate‐related BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 6.3

Comparison 6 Sensitivity analysis: 2. intention to treat; less versus more frequent, Outcome 3 Catheter colonization.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 6.4

Comparison 6 Sensitivity analysis: 2. intention to treat; less versus more frequent, Outcome 4 Catheter‐related BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 6.5

Comparison 6 Sensitivity analysis: 2. intention to treat; less versus more frequent, Outcome 5 All‐cause BSI.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Analysis 6.6

Comparison 6 Sensitivity analysis: 2. intention to treat; less versus more frequent, Outcome 6 BSI‐related deaths.

Ir a la figura de la revisiónAbrir en una pestaña nueva

Comparison 1. Primary analysis: less versus more frequent

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Infusate colonization Show forest plot	5	1374	Risk Ratio (M‐H, Fixed, 95% CI)	1.07 [0.65, 1.76]

1.1 48 hours or more versus 24 hours	3	773	Risk Ratio (M‐H, Fixed, 95% CI)	1.08 [0.62, 1.86]
1.2 72 hours or more versus 48 hours	1	173	Risk Ratio (M‐H, Fixed, 95% CI)	1.11 [0.07, 17.46]
1.3 96 hours or more versus 72 hours	1	428	Risk Ratio (M‐H, Fixed, 95% CI)	1.02 [0.28, 3.75]
2 Infusate‐related BSI Show forest plot	8	1631	Risk Ratio (M‐H, Fixed, 95% CI)	0.58 [0.25, 1.35]

2.1 48 hours or more versus 24 hours	3	321	Risk Ratio (M‐H, Fixed, 95% CI)	0.58 [0.25, 1.35]
2.2 72 hours or more versus 48 hours	4	882	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
2.3 96 hours or more versus 72 hours	1	428	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Catheter colonization Show forest plot	4	1448	Risk Ratio (M‐H, Fixed, 95% CI)	1.08 [0.94, 1.24]

3.1 48 hours or more versus 24 hours	1	182	Risk Ratio (M‐H, Fixed, 95% CI)	0.81 [0.52, 1.26]
3.2 72 hours or more versus 48 hours	2	198	Risk Ratio (M‐H, Fixed, 95% CI)	1.27 [0.80, 2.01]
3.3 96 hours or more versus 72 hours	3	1068	Risk Ratio (M‐H, Fixed, 95% CI)	1.10 [0.95, 1.28]
4 Catheter‐related BSI Show forest plot	6	1698	Risk Ratio (M‐H, Fixed, 95% CI)	1.06 [0.66, 1.68]

4.1 48 hours or more versus 24 hours	1	123	Risk Ratio (M‐H, Fixed, 95% CI)	1.08 [0.07, 16.95]
4.2 72 hours or more versus 48 hours	2	222	Risk Ratio (M‐H, Fixed, 95% CI)	0.79 [0.21, 2.94]
4.3 96 hours or more versus 72 hours	3	1353	Risk Ratio (M‐H, Fixed, 95% CI)	1.10 [0.67, 1.83]
5 All‐cause BSI Show forest plot	5	1528	Risk Ratio (M‐H, Fixed, 95% CI)	0.82 [0.48, 1.40]

5.1 48 hours or more versus 24 hours	3	871	Risk Ratio (M‐H, Fixed, 95% CI)	0.85 [0.48, 1.50]
5.2 72 hours or more versus 48 hours	2	657	Risk Ratio (M‐H, Fixed, 95% CI)	0.71 [0.18, 2.85]
6 Mortality Show forest plot	2	1355	Risk Ratio (M‐H, Fixed, 95% CI)	1.85 [1.01, 3.38]

6.1 48 hours or more versus 24 hours	2	1355	Risk Ratio (M‐H, Fixed, 95% CI)	1.85 [1.01, 3.38]
7 BSI‐related deaths Show forest plot	1	691	Risk Ratio (M‐H, Fixed, 95% CI)	14.18 [0.86, 234.13]

7.1 48 hours or more versus 24 hours	1	691	Risk Ratio (M‐H, Fixed, 95% CI)	14.18 [0.86, 234.13]

Comparison 1. Primary analysis: less versus more frequent

Ir a la tabla de la revisión

Comparison 2. Subgroup analysis: 1. site; less versus more frequent

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Infusate colonization Show forest plot	4	1251	Risk Ratio (M‐H, Fixed, 95% CI)	1.12 [0.63, 2.01]

1.1 Central	2	478	Risk Ratio (M‐H, Fixed, 95% CI)	1.01 [0.50, 2.02]
1.2 Peripheral	2	773	Risk Ratio (M‐H, Fixed, 95% CI)	1.35 [0.47, 3.87]
2 Infusate‐related BSI Show forest plot	3	653	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]

2.1 Central	2	480	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
2.2 Peripheral	1	173	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Catheter colonization Show forest plot	3	1146	Risk Ratio (M‐H, Fixed, 95% CI)	1.06 [0.91, 1.22]

3.1 Central	2	821	Risk Ratio (M‐H, Fixed, 95% CI)	1.06 [0.91, 1.25]
3.2 Peripheral	1	325	Risk Ratio (M‐H, Fixed, 95% CI)	1.03 [0.74, 1.43]
4 Catheter‐related BSI Show forest plot	3	1249	Risk Ratio (M‐H, Fixed, 95% CI)	1.11 [0.68, 1.82]

4.1 Central	3	1249	Risk Ratio (M‐H, Fixed, 95% CI)	1.11 [0.68, 1.82]
4.2 Peripheral	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]

Comparison 2. Subgroup analysis: 1. site; less versus more frequent

Ir a la tabla de la revisión

Comparison 3. Subgroup analysis: 2. infusate; less versus more frequent

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Infusate colonization Show forest plot	3	1201	Risk Ratio (M‐H, Fixed, 95% CI)	1.21 [0.54, 2.74]

1.1 PN	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
1.2 Non‐PN	3	1201	Risk Ratio (M‐H, Fixed, 95% CI)	1.21 [0.54, 2.74]
2 Infusate‐related BSI Show forest plot	5	971	Risk Ratio (M‐H, Fixed, 95% CI)	0.58 [0.25, 1.35]

2.1 PN	2	200	Risk Ratio (M‐H, Fixed, 95% CI)	0.58 [0.25, 1.35]
2.2 Non‐PN	3	771	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Catheter colonization Show forest plot	2	205	Risk Ratio (M‐H, Fixed, 95% CI)	2.57 [0.69, 9.54]

3.1 PN	2	63	Risk Ratio (M‐H, Fixed, 95% CI)	0.94 [0.17, 5.13]
3.2 Non‐PN	1	142	Risk Ratio (M‐H, Fixed, 95% CI)	10.41 [0.59, 184.73]
4 Catheter‐related BSI Show forest plot	4	804	Risk Ratio (M‐H, Fixed, 95% CI)	0.79 [0.21, 2.94]

4.1 PN	2	64	Risk Ratio (M‐H, Fixed, 95% CI)	1.25 [0.12, 12.91]
4.2 Non‐PN	3	740	Risk Ratio (M‐H, Fixed, 95% CI)	0.65 [0.13, 3.23]
5 All‐cause BSI Show forest plot	3	918	Risk Ratio (M‐H, Fixed, 95% CI)	0.78 [0.44, 1.38]

5.1 PN	1	148	Risk Ratio (M‐H, Fixed, 95% CI)	0.81 [0.44, 1.49]
5.2 Non‐PN	2	770	Risk Ratio (M‐H, Fixed, 95% CI)	0.65 [0.13, 3.23]

Comparison 3. Subgroup analysis: 2. infusate; less versus more frequent

Ir a la tabla de la revisión

Comparison 4. Subgroup analysis: 3. age group; less versus more frequent

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Infusate‐related BSI Show forest plot	4	493	Risk Ratio (M‐H, Fixed, 95% CI)	0.58 [0.25, 1.35]

1.1 Adults	3	345	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
1.2 Children	1	148	Risk Ratio (M‐H, Fixed, 95% CI)	0.58 [0.25, 1.35]
2 All‐cause BSI Show forest plot	2	416	Risk Ratio (M‐H, Fixed, 95% CI)	0.91 [0.37, 2.25]

2.1 Adults	2	293	Risk Ratio (M‐H, Fixed, 95% CI)	0.83 [0.27, 2.54]
2.2 Children	1	123	Risk Ratio (M‐H, Fixed, 95% CI)	1.08 [0.23, 5.17]

Comparison 4. Subgroup analysis: 3. age group; less versus more frequent

Ir a la tabla de la revisión

Comparison 5. Sensitivity analysis: 1. study quality; less versus more frequent

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Catheter colonization Show forest plot	4	1302	Risk Ratio (M‐H, Fixed, 95% CI)	1.08 [0.93, 1.25]

1.1 Quality A	1	769	Risk Ratio (M‐H, Fixed, 95% CI)	1.07 [0.91, 1.25]
1.2 Quality B	3	533	Risk Ratio (M‐H, Fixed, 95% CI)	1.13 [0.82, 1.55]
2 Catheter‐related BSI Show forest plot	6	1698	Risk Ratio (M‐H, Fixed, 95% CI)	1.06 [0.66, 1.68]

2.1 Quality A	1	769	Risk Ratio (M‐H, Fixed, 95% CI)	1.10 [0.67, 1.83]
2.2 Quality B	5	929	Risk Ratio (M‐H, Fixed, 95% CI)	0.84 [0.26, 2.74]
3 Mortality Show forest plot	2	1355	Risk Ratio (M‐H, Fixed, 95% CI)	1.85 [1.01, 3.38]

3.1 Quality A	1	1189	Risk Ratio (M‐H, Fixed, 95% CI)	1.79 [0.97, 3.32]
3.2 Quality B	1	166	Risk Ratio (M‐H, Fixed, 95% CI)	3.32 [0.17, 63.06]

Comparison 5. Sensitivity analysis: 1. study quality; less versus more frequent

Ir a la tabla de la revisión

Comparison 6. Sensitivity analysis: 2. intention to treat; less versus more frequent

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Infusate colonization Show forest plot	5	2011	Risk Ratio (M‐H, Fixed, 95% CI)	1.02 [0.90, 1.15]

1.1 48 hours versus 24 hours	3	1210	Risk Ratio (M‐H, Fixed, 95% CI)	1.02 [0.89, 1.18]
1.2 72 hours versus 48 hours	1	230	Risk Ratio (M‐H, Fixed, 95% CI)	1.00 [0.65, 1.56]
1.3 96 hours versus 72 hours	1	571	Risk Ratio (M‐H, Fixed, 95% CI)	1.00 [0.76, 1.32]
2 Infusate‐related BSI Show forest plot	8	2266	Risk Ratio (M‐H, Random, 95% CI)	1.15 [0.96, 1.38]

2.1 48 hours versus 24 hours	3	389	Risk Ratio (M‐H, Random, 95% CI)	1.15 [0.78, 1.70]
2.2 72 hours versus 48 hours	4	1306	Risk Ratio (M‐H, Random, 95% CI)	1.17 [0.86, 1.60]
2.3 96 hours versus 72 hours	1	571	Risk Ratio (M‐H, Random, 95% CI)	1.00 [0.75, 1.34]
3 Catheter colonization Show forest plot	4	2034	Risk Ratio (M‐H, Fixed, 95% CI)	1.07 [0.99, 1.16]

3.1 48 hours versus 24 hours	1	211	Risk Ratio (M‐H, Fixed, 95% CI)	1.34 [0.95, 1.88]
3.2 72 hours versus 48 hours	2	265	Risk Ratio (M‐H, Fixed, 95% CI)	1.11 [0.85, 1.44]
3.3 96 hours versus 72 hours	3	1558	Risk Ratio (M‐H, Fixed, 95% CI)	1.04 [0.96, 1.13]
4 Catheter‐related BSI Show forest plot	6	2521	Risk Ratio (M‐H, Random, 95% CI)	1.15 [0.93, 1.41]

4.1 48 hours versus 24 hours	1	157	Risk Ratio (M‐H, Random, 95% CI)	1.27 [0.71, 2.26]
4.2 72 hours versus 48 hours	2	426	Risk Ratio (M‐H, Random, 95% CI)	1.46 [1.20, 1.78]
4.3 96 hours versus 72 hours	3	1938	Risk Ratio (M‐H, Random, 95% CI)	1.01 [0.89, 1.14]
5 All‐cause BSI Show forest plot	5	2316	Risk Ratio (M‐H, Random, 95% CI)	1.15 [0.94, 1.42]

5.1 48 hours versus 24 hours	3	1310	Risk Ratio (M‐H, Random, 95% CI)	1.03 [0.89, 1.19]
5.2 72 hours versus 48 hours	2	1006	Risk Ratio (M‐H, Random, 95% CI)	1.23 [0.81, 1.88]
6 BSI‐related deaths Show forest plot	1	1189	Risk Ratio (M‐H, Fixed, 95% CI)	2.07 [1.64, 2.61]

6.1 48 hours versus 24 hours	1	1189	Risk Ratio (M‐H, Fixed, 95% CI)	2.07 [1.64, 2.61]

Comparison 6. Sensitivity analysis: 2. intention to treat; less versus more frequent

Ir a la tabla de la revisión

The Cochrane Library

Scolaris Language Selector Scolaris Language Selector

Idioma de la Revisión Cochrane

Idioma de la web

Scolaris Content Language Banner Portlet Scolaris Content Language Banner Portlet