Tratamiento farmacológico y nutricional para la enfermedad de McArdle (enfermedad por almacenamiento de glucógeno tipo V)
Appendices
Appendix 1. MEDLINE (OvidSP) Search Strategy
Database: Ovid MEDLINE(R) <1946 to July Week 5 2014>
Search Strategy:
‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐
1 randomized controlled trial.pt. (384910)
2 controlled clinical trial.pt. (89591)
3 randomized.ab. (281662)
4 placebo.ab. (149703)
5 drug therapy.fs. (1731271)
6 randomly.ab. (198732)
7 trial.ab. (291951)
8 groups.ab. (1271890)
9 or/1‐8 (3257293)
10 exp animals/ not humans.sh. (3992524)
11 9 not 10 (2773891)
12 Glycogen Storage Disease Type V/ (544)
13 (McArdle$ or (Glycogen Storage Disease adj5 Type V) or (Glycogen Storage Disease adj5 Type 5) or GSDV or (muscle phosphorylase adj5 deficiency)).tw. (699)
14 12 or 13 (810)
15 11 and 14 (89)
16 remove duplicates from 15 (82)
Appendix 2. EMBASE (OvidSP) Search Strategy
Database: Embase <1980 to 2014 Week 32>
Search Strategy:
‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐
1 crossover‐procedure.sh. (39769)
2 double‐blind procedure.sh. (114758)
3 single‐blind procedure.sh. (18650)
4 randomized controlled trial.sh. (347300)
5 (random$ or crossover$ or cross over$ or placebo$ or (doubl$ adj blind$) or allocat$).tw,ot. (1049629)
6 trial.ti. (160810)
7 or/1‐6 (1182235)
8 (animal/ or nonhuman/ or animal experiment/) and human/ (1279074)
9 animal/ or nonanimal/ or animal experiment/ (3238580)
10 9 not 8 (2713703)
11 7 not 10 (1085977)
12 limit 11 to embase (899999)
13 Glycogen Storage Disease Type 5/ (764)
14 (McArdle$ or (Glycogen Storage Disease adj5 Type V) or (Glycogen Storage Disease adj5 Type 5) or GSDV or (muscle phosphorylase adj5 deficiency)).tw. (769)
15 13 or 14 (1036)
16 12 and 15 (40)
17 remove duplicates from 16 (40)
Appendix 3. CENTRAL search strategy
#1 "glycogen storage disease" NEAR/6 "type v"
#2 "glycogen storage disease" NEAR/6 "type 5"
#3 gsdv
#4 (muscle phosphorylase NEAR/6 deficiency)
#5 mcardle NEAR/2 disease
#6 "muscle phosphorylase" NEAR/6 deficiency
#7 (#1 OR #2 OR #3 OR #4 OR #5 OR #6)
Appendix 4. NMD Register (CRS) search strategy
#1 "glycogen storage disease" [REFERENCE] [STANDARD]
#2 "glycogen storage diseases" [REFERENCE] [STANDARD]
#3 Mcardle*:ti or Mcardle*:ab [REFERENCE] [STANDARD]
#4 gsdv [REFERENCE] [STANDARD]
#5 "muscle phosphorylase" NEAR deficiency [REFERENCE] [STANDARD]
#6 #1 or #2 or #3 or #4 or #5 [REFERENCE] [STANDARD]
#7 (#1 or #2 or #3 or #4 or #5) AND (INREGISTER) [REFERENCE] [STANDARD]
Risk of bias summary: review authors' judgements about each risk of bias item for each included study. Red (‐) = high risk of bias; yellow (?) = unclear risk of bias, green (+) = low risk of bias.
