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Cochrane Database of Systematic Reviews

Eritropoyetina o darbepoyetina para los pacientes con cáncer

Información

DOI:
https://doi.org/10.1002/14651858.CD003407.pub5Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 12 diciembre 2012see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Hematología

Copyright:
  1. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Contraer

Autores

  • Thomy Tonia

    Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland

  • Annette Mettler

    Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland

  • Nadège Robert

    Pharmacy, Kantonsspitalapotheke Winterthur, Winterthur, Switzerland

  • Guido Schwarzer

    German Cochrane Centre, Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Freiburg, Germany

  • Jerome Seidenfeld

    Department of Quality and Guidelines, American Society of Clinical Oncology, Alexandria, USA

  • Olaf Weingart

    Cologne, Germany

  • Chris Hyde

    Peninsula Technology Assessment Group (PenTAG), University of Exeter Medical School, University of Exeter, Exeter, UK

  • Andreas Engert

    Cochrane Haematological Malignancies Group, Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany

  • Julia Bohlius

    Correspondencia a: Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland

    [email protected]

Contributions of authors

Thomy Tonia: Quality of Life analysis, searching for trials, eligibility and quality assessment, fact checking, data extraction and analysis, drafting of QoL and discussion, revision of review

Annette Mettler: Searching for trials, eligibility and quality assessment, data extraction and analysis

Nadège Robert: Searching for trials, eligibility and quality assessment, data extraction and analysis

Guido Schwarzer: Statistical and methodological advice, data analysis, content input

Olaf Weingart: eligibility and quality assessment, fact checking, creating summary of findings table

Jerome Seidenfeld: Clinical and scientific advice, content input, revision of draft review

Chris Hyde: Protocol development, searching for trials, eligibility and quality assessment, data extraction and analysis

Andreas Engert: Clinical and scientific advice, content input

Julia Bohlius: Protocol development, searching for trials, eligibility and quality assessment, data extraction and analysis, drafting and revision of review

Sources of support

Internal sources

  • Department of Internal Medicine I, University of Cologne, Germany.

  • Cochrane Haematological Malignancies Group (CHMG), Germany.

  • Institute of Social and Preventive Medicine, University of Bern, Switzerland.

External sources

  • Department of Health, UK.

Declarations of interest

Thomy Tonia, Annette Mettler, Nadège Robert, Olaf Weingart, Guido Schwarzer, Jerome Seidenfeld, Chris Hyde, Andreas Engert, Julia Bohlius: none known.

Acknowledgements

We thank all authors and co‐workers of primary studies, for which additional information and study data were provided: R. Abels, K. Aziz, J. Blohmer, D. Case, S. Cascinu, M. Cazzola, C. Coiffier, F. Dammacco, L. Del Mastro, D. Henry, Italian Cooperative Study Group, C. Kurz, T. Littlewood, V. Moebus, C. Oberhoff, A. Österborg, E. Rose, W. Ten Bokkel, N. Thatcher, JA. Thompson, NA. Throuvalas, A. Varan. We thank the pharmaceutical companies for providing us with data for various studies (Roche) and admitted additionally insight into their clinical study reports (OrthoBiotech). We also thank the pharmaceutical companies for being very helpful in answering our questions during the process of this previous versions of this review (Roche, Johnson & Johnson).

We would like to thank all previous co‐authors who contributed to previous versions of this review: Simon Langensiepen, Jayne Wilson, Margaret Piper; Sven Trelle, Susan Bayliss, Susan Brunskill, Josie Sandercock, Ben Djulbegovic, Charles Bennett.

Special thanks to Pia Raanani and Sue Richards (CHMG editors) as well as Maryann Napoli (Consumer) and Nicole Skoetz (CHMG editorial base) for critical advice and strong support of previous and current versions of this review.

The first and the second update of this review was supported by the UK Department of Health Cochrane Review Update Incentive Scheme.

Version history

Published

Title

Stage

Authors

Version

2012 Dec 12

Erythropoietin or darbepoetin for patients with cancer

Review

Thomy Tonia, Annette Mettler, Nadège Robert, Guido Schwarzer, Jerome Seidenfeld, Olaf Weingart, Chris Hyde, Andreas Engert, Julia Bohlius

https://doi.org/10.1002/14651858.CD003407.pub5

2006 Jul 19

Erythropoietin or Darbepoetin for patients with cancer

Review

Julia Bohlius, Jayne Wilson, Jerome Seidenfeld, Margret Piper, Guido Schwarzer, Josie Sandercock, Sven Trelle, Olaf Weingart, Susan Bayliss, Susan Brunskill, Benjamin Djulbegovic, Charles Bennett, Simon Langensiepen, Chris Hyde, Andreas Engert

https://doi.org/10.1002/14651858.CD003407.pub4

2005 Oct 19

Erythropoietin for patients with malignant disease

Review

Julia Bohlius, Simon Langensiepen, Guido Schwarzer, Jerome Seidenfeld, Margret Piper, C Bennet, Andreas Engert, Charles Bennett

https://doi.org/10.1002/14651858.CD003407.pub3

2004 Jul 19

Erythropoietin for patients with malignant disease

Review

Julia JB Bohlius, Simon Langensiepen, Guido Schwarzer, J Seidenfeld, Margret Piper, C Bennet, Andreas Engert, Charles Bennett

https://doi.org/10.1002/14651858.CD003407.pub2

2002 Apr 22

Erythropoietin for patients with malignant disease

Protocol

Simon SL Langensiepen, Julia Bohlius, Jerome Seidenfeld, Margret Piper, C Bennett, Guido Schwarzer, Andreas Engert, Charles Bennet

https://doi.org/10.1002/14651858.CD003407

Differences between protocol and review

In previous versions of this review, we required dosages of at least 300 U/kg body weight per week (epoetin‐a and beta) given for at least four weeks. For the current update this criterion was removed and we included studies or study arms with low dosages as well. In previous versions of this review, iron supplementation had to be identical in the study arms of a given trial. For the current update, we changed this criterion and included trials using iron supplementation in the experimental but not in the control arm as well.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.