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Cochrane Database of Systematic Reviews

Fármacos antimicrobianos para el tratamiento de la colonización por Staphylococcus aureus resistente a la meticilina

Información

DOI:
https://doi.org/10.1002/14651858.CD003340Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 20 octubre 2003see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:

  1. Grupo Cochrane de Heridas

Copyright:
  1. Copyright © 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Autores

  • Mark B Loeb

    Correspondencia a: Pathology and Molecular Medicine, Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Canada

    [email protected]

  • Cheryl Main

    Pathology and Molecular Medicine, Hamilton General Hospital, Hamilton, Canada

  • Angela Eady

    Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada

  • Cindy Walkers‐Dilks

    Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada

Contributions of authors

Mark Loeb wrote the protocol, extracted data, analysed data, and drafted the review. Cheryl Main, Cindy Walker‐Dilks, and Angela Eady extracted and analysed data, and drafted the review.

Sources of support

Internal sources

  • Hamilton Civic Hospitals, Canada.

External sources

  • Department for International Development, UK.

  • Research Foundation for Prevention of Complications Associated with Health Care, USA.

Declarations of interest

We certify that we have no affiliations with or involvement in any organization or entity with a direct financial interest in the subject matter of the review (e.g. employment, consultancy, stock ownership, honoraria, expert testimony).

Acknowledgements

We would like to thank Leonard Leibovici, Mical Paul, Alan Smyth, and Sheldon Stone for their comments about the protocol.

This review was initially developed within the Infectious Diseases Group, supported by a grant from the Department for International Development, UK. The review was transferred to the Wounds Group in May 2005.

Version history

Published

Title

Stage

Authors

Version

2003 Oct 20

Antimicrobial drugs for treating methicillin‐resistant Staphylococcus aureus colonization

Review

Mark B Loeb, Cheryl Main, Angela Eady, Cindy Walkers‐Dilks

https://doi.org/10.1002/14651858.CD003340

Differences between protocol and review

There were two major deviations from the protocol:

  1. The protocol originally was limited to comparison of agents to placebo or no therapy. But given differences in practice between hospitals that use systemic agents and those that use topical alone, we expanded this to include to head‐to‐head comparisons between various combinations of systemic and topical agents.

  2. Adverse events were originally limited to only those requiring withdrawal of therapy. In order to give a more comprehensive view of the potential drawbacks of antimicrobial agents used for eradication, we expanded this to all reported adverse events.

Notes

This review was initially developed within the Infectious Diseases Group, supported by a grant from the Department for International Development, UK. The review was transferred to the Wounds Group in May 2005.