| ARTIST | Symptomatic, diffuse in‐stent re‐stenosis (10 to 50 mm in length) at least 3 months after stent implantation |
| COBRA | Patients aged 20 to 80 years with angiographically documented coronary artery disease and clinical symptoms of angina or anginal equivalents. The target coronary stenosis was considered haemodynamically significant and eligible for the study if there was a reduction in luminal area of 70% to 99% and absolute stenosis diameters were < 1 mm for a length of at least 5 mm as visually estimated by the operator. In addition, 1 secondary criterion had to be fulfilled, such as a heavily calcified, ostial or bifurcation location, or 1 that was eccentric, diffuse or within an angulated (> 45°) segment. Exclusions: unstable angina, MI within the previous 4 weeks, previous coronary angioplasty of the target vessel within the last 2 months, poor left ventricular function (ejection fraction ≤ 30%), or any other condition that will limit long‐term prognosis |
| DART | No specific entry criteria reported. Tested effectiveness of rotational atherectomy versus PTCA in vessels < 3 mm |
| EDRES | No specific entry criteria reported |
| Eltchaninoff | Patients were eligible for the study if they had stable or unstable angina with at least 1 lesion (> 50% stenosis) in a native vessel suitable for angioplasty. Additional inclusion criteria for angioscopy were coronary artery lumen diameter between 2.5 and 3.5 mm; location of the target lesion in a straight segment of the artery; location of the lesion at least 20 mm away from the coronary ostium; absence of left main coronary artery disease. Exclusions: acute MI within 24 hours before the procedure, a re‐stenotic lesion, a total occlusion or a vein graft lesion |
| ERBAC | Patients were included if they had target lesions and vessels suitable for all 3 techniques. Patients with multi‐vessel coronary disease were also eligible, but the culprit lesion was specified as the target before coronary intervention began. Exclusions: lesion characteristics (stenosis angulation > 60°, bend stenosis with an outwardly eccentric lumen, and bifurcational lesions requiring double guidewires) and vessel (extreme proximal vessel tortuosity, saphenous bypass graft or presence of intraluminal thrombus (filling defect), and total occlusion deemed not transferable with guidewires). Patients with acute MI and those who had undergone PTCA of any other vessel within the last 4 months were also excluded |
| Guerin | Patients presenting with a significant stenosis (defined as > 60% reduction of the lumen diameter as assessed by quantitative computed angiography) in ≥ 1 major coronary vessels, a clinical indication for re‐vascularisation, and a left ventricular ejection fraction > 40%. Exclusions: MI within the last month, re‐stenosis, bypass graft lesions, presence of intraluminal defect, ostial lesions and total occlusions |
| Kwon | Patients with long, 'denovo lesions'. Lesion length > 20 mm, stenosis diameter > 50% in a native left anterior descending artery between 2 and 2.9 mm in size. Exclusions: contraindication to antiplatelet therapy, total occlusion, infarct‐related artery, left ventricular dysfunction (ejection fraction < 40%) or an inability to follow the protocol |
| Lee | Diffuse in‐stent re‐stenosis (lesion length > 10 mm, diameter stenosis N50%) in a native coronary artery with angina, demonstrable myocardial ischaemia |
| ROSTER | No specific entry criteria reported. Tested effectiveness of PTCRA versus PTCA in diffuse in‐stent re‐stenosis |
| SPORT | No specific entry criteria reported |
