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Susu formula berbanding susu ibu untuk menyusukan bayi pramatang atau berat badan yang rendah

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Abstract

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Background

Maternal breast milk may contain less nutrients than artificial formula milk but may confer important non‐nutrient advantages for preterm or low birth weight infants.

Objectives

To determine the effect of feeding with formula milk compared with maternal breast milk on rate of growth and developmental outcomes in preterm or low birth weight infants.

Search methods

The standard search strategy of the Cochrane Neonatal Review Group was used. This included electronic searches of the Cochrane Central Register of Controlled Trials Register (CENTRAL, The Cochrane Library, Issue 3, 2007), MEDLINE (1966 ‐ June 2007) and EMBASE (1980 ‐ June 2007) and CINAHL (1982 to June 2007) (all accessed via OVID) and previous reviews including cross references.

Selection criteria

Randomised controlled trials comparing feeding with formula milk versus preterm human milk in preterm or low birth weight infants.

Data collection and analysis

The standard methods of the Cochrane Neonatal Review Group were used, with separate evaluation of trial quality and data extraction by two authors.

Main results

No eligible trials were identified.

Authors' conclusions

There are no data from randomised trials of formula milk versus maternal breast milk for feeding preterm or low birth weight infants. This may relate to a perceived difficulty of allocating an alternative feed to an infant whose mother wishes to feed with her own breast milk. Maternal breast milk remains the default choice of enteral nutrition because observational studies, and meta‐analyses of trials comparing feeding with formula milk versus donor breast milk, suggest that feeding with breast milk has major non‐nutrient advantages for preterm or low birth weight infants.

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.

Ringkasan bahasa mudah

Susu formula berbanding susu ibu untuk menyusukan bayi pramatang atau berat badan rendah

Susu formula mungkin mengandungi lebih banyak nutrien berbanding susu ibu tetapi ia tidak mempunyai antibodi dan bahan lain‐lain yang hadir dalam susu ibu yang dapat melindungi dan meningkatkan perkembangan usus yang belum matang untuk bayi pramatang atau mempunyai berat badan yang rendah. Tiada ujian yang membandingkan pemakanan dengan susu formula berbanding susu ibu mereka sendiri dikenal pasti. Walau bagaimanapun, memandangkan ulasan Cochrane lain mendapati bahawa pemakanan susu formula berbanding dengan susu penderma meningkatkan risiko masalah usus yang serius dalam bayi pramatang atau berat badan rendah, maka ia adalah tidak mungkin bahawa ujian ini akan diterima oleh ibu dan penjaga.