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Comparison 1 Antibiotics versus control, Outcome 1 Mortality.
Figuras y tablas -
Analysis 1.1

Comparison 1 Antibiotics versus control, Outcome 1 Mortality.

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Comparison 1 Antibiotics versus control, Outcome 2 Infected Pancreatic Necrosis.
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Analysis 1.2

Comparison 1 Antibiotics versus control, Outcome 2 Infected Pancreatic Necrosis.

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Comparison 1 Antibiotics versus control, Outcome 3 Operative Treatment.
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Analysis 1.3

Comparison 1 Antibiotics versus control, Outcome 3 Operative Treatment.

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Comparison 1 Antibiotics versus control, Outcome 4 Non‐Pancreatic Infections.
Figuras y tablas -
Analysis 1.4

Comparison 1 Antibiotics versus control, Outcome 4 Non‐Pancreatic Infections.

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Comparison 1 Antibiotics versus control, Outcome 5 Fungal Infection.
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Analysis 1.5

Comparison 1 Antibiotics versus control, Outcome 5 Fungal Infection.

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Comparison 2 Betalactam versus control, Outcome 1 Mortality (beta‐lactams).
Figuras y tablas -
Analysis 2.1

Comparison 2 Betalactam versus control, Outcome 1 Mortality (beta‐lactams).

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Comparison 2 Betalactam versus control, Outcome 2 Infected Pancreatic Necrosis (beta‐lactams).
Figuras y tablas -
Analysis 2.2

Comparison 2 Betalactam versus control, Outcome 2 Infected Pancreatic Necrosis (beta‐lactams).

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Comparison 2 Betalactam versus control, Outcome 3 Operative Treatment (beta‐lactam).
Figuras y tablas -
Analysis 2.3

Comparison 2 Betalactam versus control, Outcome 3 Operative Treatment (beta‐lactam).

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Comparison 2 Betalactam versus control, Outcome 4 Non‐Pancreatic Infections (beta‐lactams).
Figuras y tablas -
Analysis 2.4

Comparison 2 Betalactam versus control, Outcome 4 Non‐Pancreatic Infections (beta‐lactams).

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Comparison 2 Betalactam versus control, Outcome 5 Fungal Infection (beta‐lactams).
Figuras y tablas -
Analysis 2.5

Comparison 2 Betalactam versus control, Outcome 5 Fungal Infection (beta‐lactams).

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Comparison 3 Quinolones versus control, Outcome 1 Mortality (quinolones).
Figuras y tablas -
Analysis 3.1

Comparison 3 Quinolones versus control, Outcome 1 Mortality (quinolones).

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Comparison 3 Quinolones versus control, Outcome 2 Infected Pancreatic Necrosis (quinolones).
Figuras y tablas -
Analysis 3.2

Comparison 3 Quinolones versus control, Outcome 2 Infected Pancreatic Necrosis (quinolones).

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Comparison 3 Quinolones versus control, Outcome 3 Fungal Infection (quinolones).
Figuras y tablas -
Analysis 3.3

Comparison 3 Quinolones versus control, Outcome 3 Fungal Infection (quinolones).

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Comparison 1. Antibiotics versus control

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mortality Show forest plot

5

294

Odds Ratio (M‐H, Fixed, 95% CI)

0.37 [0.17, 0.83]

2 Infected Pancreatic Necrosis Show forest plot

5

294

Odds Ratio (M‐H, Fixed, 95% CI)

0.62 [0.35, 1.09]

3 Operative Treatment Show forest plot

4

268

Odds Ratio (M‐H, Fixed, 95% CI)

0.72 [0.41, 1.27]

4 Non‐Pancreatic Infections Show forest plot

3

208

Odds Ratio (M‐H, Fixed, 95% CI)

0.58 [0.31, 1.09]

5 Fungal Infection Show forest plot

5

294

Odds Ratio (M‐H, Fixed, 95% CI)

0.83 [0.30, 2.27]
Figuras y tablas -
Comparison 1. Antibiotics versus control
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Comparison 2. Betalactam versus control

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mortality (beta‐lactams) Show forest plot

3

192

Odds Ratio (M‐H, Fixed, 95% CI)

0.34 [0.13, 0.91]

2 Infected Pancreatic Necrosis (beta‐lactams) Show forest plot

3

192

Odds Ratio (M‐H, Fixed, 95% CI)

0.41 [0.20, 0.85]

3 Operative Treatment (beta‐lactam) Show forest plot

3

192

Odds Ratio (M‐H, Fixed, 95% CI)

0.55 [0.28, 1.07]

4 Non‐Pancreatic Infections (beta‐lactams) Show forest plot

2

132

Odds Ratio (M‐H, Fixed, 95% CI)

0.45 [0.19, 1.06]

5 Fungal Infection (beta‐lactams) Show forest plot

3

192

Odds Ratio (M‐H, Fixed, 95% CI)

0.61 [0.16, 2.27]
Figuras y tablas -
Comparison 2. Betalactam versus control
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Comparison 3. Quinolones versus control

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mortality (quinolones) Show forest plot

2

102

Odds Ratio (M‐H, Fixed, 95% CI)

0.45 [0.11, 1.74]

2 Infected Pancreatic Necrosis (quinolones) Show forest plot

2

102

Odds Ratio (M‐H, Fixed, 95% CI)

1.29 [0.49, 3.41]

3 Fungal Infection (quinolones) Show forest plot

2

102

Odds Ratio (M‐H, Fixed, 95% CI)

1.32 [0.26, 6.63]
Figuras y tablas -
Comparison 3. Quinolones versus control
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