Intervenciones psicológicas para la cardiopatía coronaria
Appendices
Appendix 1. Search strategies 2016
Additional terms were added in 2015 and no date restrictions were applied to those, only to the previously used terms. When re‐run in 2016, date limits were applied to all terms. The CENTRAL search has been restricted by publication year and the other searches were limited by entry date.
CENTRAL 2015
#1 MeSH descriptor: [Myocardial Ischemia] explode all trees
#2 (myocard* near isch*mi*)
#3 isch*mi* near heart
#4 MeSH descriptor: [Coronary Artery Bypass] explode all trees
#5 coronary
#6 MeSH descriptor: [Coronary Disease] explode all trees
#7 MeSH descriptor: [Myocardial Revascularization] explode all trees
#8 MeSH descriptor: [Myocardial Infarction] explode all trees
#9 myocard* near infarct*
#10 heart near infarct*
#11 MeSH descriptor: [Angina Pectoris] explode all trees
#12 angina
#13 MeSH descriptor: [Heart Failure] explode all trees
#14 heart and (failure or attack)
#15 MeSH descriptor: [Heart Diseases] explode all trees
#16 heart and disease*
#17 myocard*
#18 cardiac*
#19 CABG
#20 PTCA
#21 stent* and (heart or cardiac*)
#22 MeSH descriptor: [Heart Bypass, Left] explode all trees
#23 MeSH descriptor: [Heart Bypass, Right] explode all trees
#24 #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 or #14 or #15 or #16 or #17 or #18 or #19 or #20 or #21 or #22 or #23
#25 MeSH descriptor: [Psychotherapy] explode all trees
#26 psychotherap*
#27 psycholog* near intervent*
#28 relax*
#29 MeSH descriptor: [Relaxation Therapy] explode all trees
#30 MeSH descriptor: [Counseling] explode all trees
#31 counsel*ing
#32 MeSH descriptor: [Cognitive Therapy] explode all trees
#33 MeSH descriptor: [Behavior Therapy] explode all trees
#34 (behavio*r*) near/4 (modif* or therap* or rehab* or change)
#35 MeSH descriptor: [Stress, Psychological] explode all trees
#36 stress near manage*
#37 cognitive* near therap*
#38 MeSH descriptor: [Meditation] explode all trees
#39 meditat*
#40 MeSH descriptor: [Anxiety] explode all trees
#41 (manage*) near (anxiety or depres*)
#42 CBT
#43 hypnotherap*
#44 goal near/3 setting
#45 (psycho‐educat*) or (psychoeducat*)
#46 motivat* near interv*
#47 MeSH descriptor: [Psychopathology] explode all trees
#48 psychopathol*
#49 MeSH descriptor: [Autogenic Training] explode all trees
#50 autogenic*
#51 self near (manage* or care or motivat*)
#52 distress*
#53 psychosocial* or psycho‐social
#54 #25 or #26 or #27 or #28 or #29 or #30 or #31 or #32 or #33 or #34 or #35 or #36 or #37 or #38 or #39 or #40 or #41 or #42 or #43 or #44 or #45 or #46 or #47 or #48 or #49 or #50 or #51 or #52 or #53
#55 #24 and #54
#56 MeSH descriptor: [Percutaneous Coronary Intervention] explode all trees
#57 "percutaneous coronary" near/2 (interven* or revascular*)
#58 MeSH descriptor: [Angioplasty] explode all trees
#59 angioplast*
#60 (coronary or arterial) near/4 dilat*
#61 endoluminal next repair*
#62 MeSH descriptor: [Stents] explode all trees
#63 stent*
#64 pci or ptca
#65 MeSH descriptor: [Atherectomy] explode all trees
#66 atherectom*
#67 "acute coronary syndrom*"
#68 #56 or #57 or #58 or #59 or #60 or #61 or #62 or #63 or #64 or #65 or #66 or #67
#69 #68 or #24
#70 #69 and #54
#71 #70 not #55
#72 #55 Publication Year from 2009 to 2015
#73 #72 or #71
CENTRAL 2016
#1 MeSH descriptor: [Myocardial Ischemia] explode all trees
#2 (myocard* near isch*mi*)
#3 isch*mi* near heart
#4 MeSH descriptor: [Coronary Artery Bypass] explode all trees
#5 coronary
#6 MeSH descriptor: [Coronary Disease] explode all trees
#7 MeSH descriptor: [Myocardial Revascularization] explode all trees
#8 MeSH descriptor: [Myocardial Infarction] explode all trees
#9 myocard* near infarct*
#10 heart near infarct*
#11 MeSH descriptor: [Angina Pectoris] explode all trees
#12 angina
#13 MeSH descriptor: [Heart Failure] explode all trees
#14 heart and (failure or attack)
#15 MeSH descriptor: [Heart Diseases] explode all trees
#16 heart and disease*
#17 myocard*
#18 cardiac*
#19 CABG
#20 PTCA
#21 stent* and (heart or cardiac*)
#22 MeSH descriptor: [Heart Bypass, Left] explode all trees
#23 MeSH descriptor: [Heart Bypass, Right] explode all trees
#24 #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 or #14 or #15 or #16 or #17 or #18 or #19 or #20 or #21 or #22 or #23
#25 MeSH descriptor: [Percutaneous Coronary Intervention] explode all trees
#26 "percutaneous coronary" near/2 (interven* or revascular*)
#27 MeSH descriptor: [Angioplasty] explode all trees
#28 angioplast*
#29 (coronary or arterial) near/4 dilat*
#30 endoluminal next repair*
#31 MeSH descriptor: [Stents] explode all trees
#32 stent*
#33 pci or ptca
#34 MeSH descriptor: [Atherectomy] explode all trees
#35 atherectom*
#36 "acute coronary syndrom*"
#37 #25 or #26 or #27 or #28 or #29 or #30 or #31 or #32 or #33 or #34 or #35 or #36
#38 #24 or #37
#39 MeSH descriptor: [Psychotherapy] explode all trees
#40 psychotherap*
#41 psycholog* near intervent*
#42 relax*
#43 MeSH descriptor: [Relaxation Therapy] explode all trees
#44 MeSH descriptor: [Counseling] explode all trees
#45 counsel*ing
#46 MeSH descriptor: [Cognitive Therapy] explode all trees
#47 MeSH descriptor: [Behavior Therapy] explode all trees
#48 (behavio*r*) near/4 (modif* or therap* or rehab* or change)
#49 MeSH descriptor: [Stress, Psychological] explode all trees
#50 stress near manage*
#51 cognitive* near therap*
#52 MeSH descriptor: [Meditation] explode all trees
#53 meditat*
#54 MeSH descriptor: [Anxiety] explode all trees
#55 (manage*) near (anxiety or depres*)
#56 CBT
#57 hypnotherap*
#58 goal near/3 setting
#59 (psycho‐educat*) or (psychoeducat*)
#60 motivat* near interv*
#61 MeSH descriptor: [Psychopathology] explode all trees
#62 psychopathol*
#63 MeSH descriptor: [Autogenic Training] explode all trees
#64 autogenic*
#65 self near (manage* or care or motivat*)
#66 distress*
#67 psychosocial* or psycho‐social
#68 #39 or #40 or #41 or #42 or #43 or #44 or #45 or #46 or #47 or #48 or #49 or #50 or #51 or #52 or #53 or #54 or #55 or #56 or #57 or #58 or #59 or #60 or #61 or #62 or #63 or #64 or #65 or #66 or #67
#69 #38 and #68
#70 #69 Publication Year from 2015 to 2016
MEDLINE 2015
1. exp Myocardial Ischemia/
2. (myocard* adj4 (ischaemi* or ischemi*)).tw.
3. exp Coronary Artery Bypass/
4. ((ischaemi* or ischemi*) adj4 heart).tw.
5. coronary.tw.
6. exp Coronary Disease/
7. exp Myocardial Revascularization/
8. exp Myocardial Infarction/
9. (myocard* adj4 infarct*).tw.
10. (heart adj4 infarct*).tw.
11. exp Angina Pectoris/
12. angina.tw.
13. exp Heart Failure/
14. (heart adj6 failure).tw.
15. or/1‐14
16. exp Heart Diseases/
17. myocard*.tw.
18. cardiac*.tw.
19. CABG.tw.
20. PTCA.tw.
21. (stent* and heart).tw.
22. Heart Bypass, Left/ or Heart Bypass, Right/
23. (heart adj4 disease*).tw.
24. or/16‐23
25. exp Psychotherapy/
26. psychotherap*.tw.
27. (psycholog* adj intervent*).tw.
28. relax*.tw.
29. exp Relaxation Techniques/
30. exp Counseling/
31. (counselling or counseling).tw.
32. ((behavior* or behaviour*) adj4 (modify or modificat* or therap* or change)).tw.
33. Stress, Psychological/
34. (stress adj4 management).tw.
35. (cognitive adj4 therap*).tw.
36. meditat*.tw.
37. anxiety.tw.
38. (manage* adj2 (anxiety or depres*)).tw.
39. CBT.tw.
40. hypnotherap*.tw.
41. (goal* adj3 setting).tw.
42. (psycho‐educat* or psychoeducat*).tw.
43. (motivat* adj3 interv*).tw.
44. Psychopathology/
45. psychopathol*.tw.
46. psychosocial*.tw.
47. distress*.tw.
48. Health Education/
49. (health adj2 education).tw.
50. (heart adj manual).tw.
51. Autogenic Training/
52. autogenic*.tw.
53. or/25‐52
54. 24 or 15
55. 53 and 54
56. randomized controlled trial.pt.
57. controlled clinical trial.pt.
58. randomized.ab.
59. placebo.ab.
60. drug therapy.fs.
61. randomly.ab.
62. trial.ab.
63. groups.ab.
64. 56 or 57 or 58 or 59 or 60 or 61 or 62 or 63
65. exp animals/ not humans.sh.
66. 64 not 65
67. 55 and 66
68. exp Percutaneous Coronary Intervention/
69. (percutaneous coronary adj2 (interven* or revascular*)).tw.
70. exp Angioplasty/
71. angioplast*.tw.
72. ((coronary or arterial) adj4 dilat*).tw.
73. endoluminal repair*.tw.
74. exp Stents/
75. stent*.tw.
76. (pci or ptca).tw.
77. exp Atherectomy/
78. atherectom*.tw.
79. acute coronary syndrom*.tw.
80. or/68‐79
81. 54 or 80
82. 53 and 66 and 81
83. 82 not 67
84. (2009* or 2010* or 2011* or 2012* or 2013* or 2014* or 2015*).ed.
85. 67 and 84
86. 83 or 85
MEDLINE 2016
1. exp Myocardial Ischemia/
2. (myocard* adj4 (ischaemi* or ischemi*)).tw.
3. exp Coronary Artery Bypass/
4. ((ischaemi* or ischemi*) adj4 heart).tw.
5. coronary.tw.
6. exp Coronary Disease/
7. exp Myocardial Revascularization/
8. exp Myocardial Infarction/
9. (myocard* adj4 infarct*).tw.
10. (heart adj4 infarct*).tw.
11. exp Angina Pectoris/
12. angina.tw.
13. exp Heart Failure/
14. (heart adj6 failure).tw.
15. 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10 or 11 or 12 or 13 or 14
16. exp Heart Diseases/
17. myocard*.tw.
18. cardiac*.tw.
19. CABG.tw.
20. PTCA.tw.
21. (stent* and heart).tw.
22. Heart Bypass, Left/ or Heart Bypass, Right/
23. (heart adj4 disease*).tw.
24. 16 or 17 or 18 or 19 or 20 or 21 or 22 or 23
25. exp Percutaneous Coronary Intervention/
26. (percutaneous coronary adj2 (interven* or revascular*)).tw.
27. exp Angioplasty/
28. angioplast*.tw.
29. ((coronary or arterial) adj4 dilat*).tw.
30. endoluminal repair*.tw.
31. exp Stents/
32. stent*.tw.
33. (pci or ptca).tw.
34. exp Atherectomy/
35. atherectom*.tw.
36. acute coronary syndrom*.tw.
37. 25 or 26 or 27 or 28 or 29 or 30 or 31 or 32 or 33 or 34 or 35 or 36
38. 15 or 24 or 37
39. exp Psychotherapy/
40. psychotherap*.tw.
41. (psycholog* adj intervent*).tw.
42. relax*.tw.
43. exp Relaxation Techniques/
44. exp Counseling/
45. (counselling or counseling).tw.
46. ((behavior* or behaviour*) adj4 (modify or modificat* or therap* or change)).tw.
47. Stress, Psychological/
48. (stress adj4 management).tw.
49. (cognitive adj4 therap*).tw.
50. meditat*.tw.
51. anxiety.tw.
52. (manage* adj2 (anxiety or depres*)).tw.
53. CBT.tw.
54. hypnotherap*.tw.
55. (goal* adj3 setting).tw.
56. (psycho‐educat* or psychoeducat*).tw.
57. (motivat* adj3 interv*).tw.
58. Psychopathology/
59. psychopathol*.tw.
60. psychosocial*.tw.
61. distress*.tw.
62. Health Education/
63. (health adj2 education).tw.
64. (heart adj manual).tw.
65. Autogenic Training/
66. autogenic*.tw.
67. 39 or 40 or 41 or 42 or 43 or 44 or 45 or 46 or 47 or 48 or 49 or 50 or 51 or 52 or 53 or 54 or 55 or 56 or 57 or 58 or 59 or 60 or 61 or 62 or 63 or 64 or 65 or 66
68. 38 and 67
69. randomized controlled trial.pt.
70. controlled clinical trial.pt.
71. randomized.ab.
72. placebo.ab.
73. drug therapy.fs.
74. randomly.ab.
75. trial.ab.
76. groups.ab.
77. 69 or 70 or 71 or 72 or 73 or 74 or 75 or 76
78. exp animals/ not humans.sh.
79. 77 not 78
80. 68 and 79
81. (2015* or 2016*).ed.
82. 80 and 81
Embase 2015
1. heart disease/
2. (myocard* adj2 (ischaemi* or ischemi*)).tw.
3. ((ischaemi* or ischemi*) adj4 heart).tw.
4. coronary artery disease/
5. transluminal coronary angioplasty/
6. (coronary adj4 (disease* or bypass* or thrombo* or angioplast*)).tw.
7. heart infarction/
8. (myocard* adj2 infarct*).tw.
9. (heart adj2 infarc*).tw.
10. heart muscle revascularization/
11. angina pectoris/
12. angina.tw.
13. (heart adj2 failure).tw.
14. (heart adj2 disease*).tw.
15. cardiac*.tw.
16. CABG.tw.
17. PTCA.tw.
18. (stent* and heart).tw.
19. extracorporeal circulation/
20. or/1‐19
21. psychotherapy/
22. psychotherap*.tw.
23. relax*.tw.
24. (psycholog* adj4 intervent*).tw.
25. relaxation training/
26. exp counseling/
27. (counselling or counseling).tw.
28. ((behavior* or behaviour*) adj4 (modify or modificat* or therapy* or change)).tw.
29. stress management/
30. (stress adj3 management).tw.
31. exp meditation/
32. meditat*.tw.
33. (manage* adj2 (anxiety or depres*)).tw.
34. CBT.tw.
35. hypnotherap*.tw.
36. (goal* adj3 setting).tw.
37. (motivat* adj4 intervent*).tw.
38. psychosocial care/
39. psychosocial rehabilitation/
40. psychosocial.tw.
41. autogenic training/
42. autogenic.tw.
43. or/21‐42
44. 20 and 43
45. random$.tw.
46. factorial$.tw.
47. crossover$.tw.
48. cross over$.tw.
49. cross‐over$.tw.
50. placebo$.tw.
51. (doubl$ adj blind$).tw.
52. (singl$ adj blind$).tw.
53. assign$.tw.
54. allocat$.tw.
55. volunteer$.tw.
56. crossover procedure/
57. double blind procedure/
58. randomized controlled trial/
59. single blind procedure/
60. 45 or 46 or 47 or 48 or 49 or 50 or 51 or 52 or 53 or 54 or 55 or 56 or 57 or 58 or 59
61. (animal/ or nonhuman/) not human/
62. 60 not 61
63. 44 and 62
64. (2009* or 2010* or 2011* or 2012* or 2013* or 2014* or 2015* or 2015*).dd.
65. (2009* or 2010* or 2011* or 2012* or 2013* or 2014* or 2015* or 2015*).em.
66. 64 or 65
67. 63 and 66
68. percutaneous coronary intervention/
69. (percutaneous coronary adj2 (interven* or revascular*)).tw.
70. exp angioplasty/
71. angioplast*.tw.
72. ((coronary or arterial) adj4 dilat*).tw.
73. endoluminal repair*.tw.
74. exp stent/
75. stent*.tw.
76. (pci or ptca).tw.
77. exp atherectomy/
78. atherectom*.tw.
79. acute coronary syndrom*.tw.
80. or/68‐79
81. 20 or 80
82. 43 and 62 and 81
83. 82 not 63
84. 67 or 83
Embase 2016
1. heart disease/
2. (myocard* adj2 (ischaemi* or ischemi*)).tw.
3. ((ischaemi* or ischemi*) adj4 heart).tw.
4. coronary artery disease/
5. transluminal coronary angioplasty/
6. (coronary adj4 (disease* or bypass* or thrombo* or angioplast*)).tw.
7. heart infarction/
8. (myocard* adj2 infarct*).tw.
9. (heart adj2 infarc*).tw.
10. heart muscle revascularization/
11. angina pectoris/
12. angina.tw.
13. (heart adj2 failure).tw.
14. (heart adj2 disease*).tw.
15. cardiac*.tw.
16. CABG.tw.
17. PTCA.tw.
18. (stent* and heart).tw.
19. extracorporeal circulation/
20. or/1‐19
21. percutaneous coronary intervention/
22. (percutaneous coronary adj2 (interven* or revascular*)).tw.
23. exp angioplasty/
24. angioplast*.tw.
25. ((coronary or arterial) adj4 dilat*).tw.
26. endoluminal repair*.tw.
27. exp stent/
28. stent*.tw.
29. (pci or ptca).tw.
30. exp atherectomy/
31. atherectom*.tw.
32. acute coronary syndrom*.tw.
33. 21 or 22 or 23 or 24 or 25 or 26 or 27 or 28 or 29 or 30 or 31 or 32
34. 20 or 33
35. psychotherapy/
36. psychotherap*.tw.
37. relax*.tw.
38. (psycholog* adj4 intervent*).tw.
39. relaxation training/
40. exp counseling/
41. (counselling or counseling).tw.
42. ((behavior* or behaviour*) adj4 (modify or modificat* or therapy* or change)).tw.
43. stress management/
44. (stress adj3 management).tw.
45. exp meditation/
46. meditat*.tw.
47. (manage* adj2 (anxiety or depres*)).tw.
48. CBT.tw.
49. hypnotherap*.tw.
50. (goal* adj3 setting).tw.
51. (motivat* adj4 intervent*).tw.
52. psychosocial care/
53. psychosocial rehabilitation/
54. psychosocial.tw.
55. autogenic training/
56. autogenic.tw.
57. 35 or 36 or 37 or 38 or 39 or 40 or 41 or 42 or 43 or 44 or 45 or 46 or 47 or 48 or 49 or 50 or 51 or 52 or 53 or 54 or 55 or 56
58. 34 and 57
59. random$.tw.
60. factorial$.tw.
61. crossover$.tw.
62. cross over$.tw.
63. cross‐over$.tw.
64. placebo$.tw.
65. (doubl$ adj blind$).tw.
66. (singl$ adj blind$).tw.
67. assign$.tw.
68. allocat$.tw.
69. volunteer$.tw.
70. crossover procedure/
71. double blind procedure/
72. randomized controlled trial/
73. single blind procedure/
74. 59 or 60 or 61 or 62 or 63 or 64 or 65 or 66 or 67 or 68 or 69 or 70 or 71 or 72 or 73
75. (animal/ or nonhuman/) not human/
76. 74 not 75
77. 58 and 76
78. (2015* or 2016*).dd,em.
79. 77 and 78
PsycINFO 2015
1. heart disorders/
2. myocardial infarctions/
3. exp Ischemia/
4. heart surgery/
5. angioplasty.tw.
6. (heart adj bypass).tw.
7. coronary.tw.
8. (ischemi* or ischaemi*).tw.
9. (myocard* adj2 infarct*).tw.
10. (heart adj2 (infarc* or failure or attack)).tw.
11. angina.tw.
12. (heart adj6 disease*).tw.
13. myocard*.tw.
14. cardiac*.tw.
15. CABG.tw.
16. PTCA.tw.
17. or/1‐16
18. exp Psychotherapy/
19. psychotherap*.tw.
20. treatment/
21. (psycholog* adj intervent*).tw.
22. exp Counseling/
23. Coping Behavior/
24. exp Meditation/
25. Autogenic Training/
26. relax*.tw.
27. (counselling or counseling).tw.
28. ((behaviour or behavior) adj3 (modif* or therap* or rehabilit* or change)).tw.
29. (stress adj3 manage*).tw.
30. meditat*.tw.
31. (manage* adj2 (anxiety or depres*)).tw.
32. (CBT or (cognitiv* adj2 therap*)).tw.
33. hypnotherap*.tw.
34. (psycho‐educat* or psychoeducat*).tw.
35. (motivat* adj4 intervent*).tw.
36. (self adj2 manag*).tw.
37. autogenic*.tw.
38. (goal* adj3 setting).tw.
39. or/18‐38
40. 17 and 39
41. random$.tw.
42. factorial$.tw.
43. crossover$.tw.
44. cross‐over$.tw.
45. placebo$.tw.
46. (doubl$ adj blind$).tw.
47. (singl$ adj blind$).tw.
48. assign$.tw.
49. allocat$.tw.
50. volunteer$.tw.
51. control*.tw.
52. "2000".md.
53. or/41‐52
54. 40 and 53
55. (2009* or 2010* or 2011* or 2012* or 2013* or 2014* or 2015*).up.
56. 54 and 55
57. (percutaneous coronary adj2 (interven* or revascular*)).tw.
58. angioplast*.tw.
59. ((coronary or arterial) adj4 dilat*).tw.
60. endoluminal repair*.tw.
61. stent*.tw.
62. (pci or ptca).tw.
63. atherectom*.tw.
64. acute coronary syndrom*.tw.
65. or/57‐64
66. 17 or 65
67. 39 and 53 and 66
68. 67 not 54
69. 56 or 68
PsycINFO 2016
1. heart disorders/
2. myocardial infarctions/
3. exp Ischemia/
4. heart surgery/
5. angioplasty.tw.
6. (heart adj bypass).tw.
7. coronary.tw.
8. (ischemi* or ischaemi*).tw.
9. (myocard* adj2 infarct*).tw.
10. (heart adj2 (infarc* or failure or attack)).tw.
11. angina.tw.
12. (heart adj6 disease*).tw.
13. myocard*.tw.
14. cardiac*.tw.
15. CABG.tw.
16. PTCA.tw.
17. or/1‐16
18. (percutaneous coronary adj2 (interven* or revascular*)).tw.
19. angioplast*.tw.
20. ((coronary or arterial) adj4 dilat*).tw.
21. endoluminal repair*.tw.
22. stent*.tw.
23. (pci or ptca).tw.
24. atherectom*.tw.
25. acute coronary syndrom*.tw.
26. 18 or 19 or 20 or 21 or 22 or 23 or 24 or 25
27. 17 or 26
28. exp Psychotherapy/
29. psychotherap*.tw.
30. treatment/
31. (psycholog* adj intervent*).tw.
32. exp Counseling/
33. Coping Behavior/
34. exp Meditation/
35. Autogenic Training/
36. relax*.tw.
37. (counselling or counseling).tw.
38. ((behaviour or behavior) adj3 (modif* or therap* or rehabilit* or change)).tw.
39. (stress adj3 manage*).tw.
40. meditat*.tw.
41. (manage* adj2 (anxiety or depres*)).tw.
42. (CBT or (cognitiv* adj2 therap*)).tw.
43. hypnotherap*.tw.
44. (psycho‐educat* or psychoeducat*).tw.
45. (motivat* adj4 intervent*).tw.
46. (self adj2 manag*).tw.
47. autogenic*.tw.
48. (goal* adj3 setting).tw.
49. 28 or 29 or 30 or 31 or 32 or 33 or 34 or 35 or 36 or 37 or 38 or 39 or 40 or 41 or 42 or 43 or 44 or 45 or 46 or 47 or 48
50. 27 and 49
51. random$.tw.
52. factorial$.tw.
53. crossover$.tw.
54. cross‐over$.tw.
55. placebo$.tw.
56. (doubl$ adj blind$).tw.
57. (singl$ adj blind$).tw.
58. assign$.tw.
59. allocat$.tw.
60. volunteer$.tw.
61. control*.tw.
62. "2000".md.
63. 51 or 52 or 53 or 54 or 55 or 56 or 57 or 58 or 59 or 60 or 61 or 62
64. 50 and 63
65. (2015* or 2016*).up.
66. 64 and 65
CINAHL 2015
S67 S54 OR S66
S66 S65 not S52
S65 S45 AND S51 AND S64
S64 S22 OR S63
S63 S55 OR S56 OR S57 OR S58 OR S59 OR S60 OR S61 OR S62
S62 TI (acute coronary syndrom*) or AB (acute coronary syndrom*)
S61 TI atherectom* or AB atherectom*
S60 TI (pci or ptca) or AB (pci or ptca)
S59 TI stent* or AB stent*
S58 TI (endoluminal repair*) or AB (endoluminal repair*)
S57 TI ((coronary or arterial) and dilat*) or AB ((coronary or arterial) and dilat*)
S56 TI angioplast* or AB angioplast*
S55 TI (percutaneous coronary and (interven* or revascular*)) or AB (percutaneous coronary and (interven* or revascular*))
S54 S52 AND S53
S53 EM 20090101‐20150129
S52 S46 AND S51
S51 S47 OR S48 OR S49 OR S50
S50 TI ((SINGL* OR DOUBLE* OR TRIPLE* OR TREBLE*) AND (BLIND* OR MASK*)) or AB ((SINGL* OR DOUBLE* OR TRIPLE* OR TREBLE*) AND (BLIND* OR MASK*))
S49 TI (RANDOM* OR PLACEBO*) or AB (RANDOM* OR PLACEBO*)
S48 PT clinical trial
S47 (MH "Clinical Trials+")
S46 S22 AND S45
S45 S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35 OR S36 OR S37 OR S38 OR S39 OR S40 OR S41 OR S42 OR S43 OR S44
S44 TI autogenic* or AB autogenic*
S43 TI psychosocial* or AB psychosocial*
S42 TI (motivat* and (interv* or intervent*)) or AB (motivat* and (interv* or intervent*))
S41 TI (psycho‐educat* or psychoeducat*) or AB (psycho‐educat* or psychoeducat*)
S40 TI (goal* and setting) or AB (goal* and setting)
S39 TI hypnotherap* or AB hypnotherap*
S38 TI CBT or AB CBT
S37 TI (manage* and (anxiety or depress*)) or AB (manage* and (anxiety or depress*))
S36 (MH "Anxiety+")
S35 TI meditat* or AB meditat*
S34 (MH "Meditation")
S33 TI (cognitive and therap*) or AB (cognitive and therap*)
S32 TI (stress and manag*) or AB (stress and manag*)
S31 (MH "Stress Management")
S30 TI ((behavior* or behaviour*) and (modify or modificat* or therap* or change)) or AB ((behavior* or behaviour*) and (modify or modificat* or therap* or change))
S29 (MH "Counseling+")
S28 TI (counselling or counseling) or AB (counselling or counseling)
S27 (MH "Relaxation Techniques")
S26 TI relax* or AB relax*
S25 TI (psycholog* and intervent*) or AB (psycholog* and intervent*)
S24 TI psychotherap* or AB psychotherap*
S23 (MH "Psychotherapy+")
S22 S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21
S21 (MH "Angina Pectoris")
S20 (MH "Heart Failure")
S19 (MH "Cardiovascular Diseases")
S18 (MH "Heart Diseases")
S17 (MH "Myocardial Revascularization")
S16 (MH "Myocardial Diseases")
S15 (MH "Cardiac Patients")
S14 (MH "Coronary Disease")
S13 (MH "Coronary Artery Bypass")
S12 (MH "Myocardial Infarction")
S11 (MH "Myocardial Ischemia")
S10 TI (stent* and (heart or cardiac*)) or AB (stent* and (heart or cardiac*))
S9 TI PTCA or AB PTCA
S8 TI CABG or AB CABG
S7 TI cardiac* or AB cardiac*
S6 TI (heart and diseas*) or AB (heart and diseas*)
S5 TI (heart and failure) or AB (heart and failure)
S4 TI angina or AB angina
S3 TI ((myocard* or heart) and infarc*) or AB ((myocard* or heart) and infarc*)
S2 TI coronary or AB coronary
S1 TI ((myocard* or heart) and (ischaemi* or ischemi*)) or AB ((myocard* or heart) and (ischaemi* or ischemi*))
CINAHL 2016
S64 S62 AND S63
S63 EM 20150101‐20160505
S62 S56 AND S61
S61 S57 OR S58 OR S59 OR S60
S60 TI ((SINGL* OR DOUBLE* OR TRIPLE* OR TREBLE*) AND (BLIND* OR MASK*)) or AB ((SINGL* OR DOUBLE* OR TRIPLE* OR TREBLE*) AND (BLIND* OR MASK*))
S59 TI (RANDOM* OR PLACEBO*) or AB (RANDOM* OR PLACEBO*)
S58 PT clinical trial
S57 (MH "Clinical Trials+")
S56 S32 AND S55
S55 S33 OR S34 OR S35 OR S36 OR S37 OR S38 OR S39 OR S40 OR S41 OR S42 OR S43 OR S44 OR S45 OR S46 OR S47 OR S48 OR S49 OR S50 OR S51 OR S52 OR S53 OR S54
S54 TI autogenic* or AB autogenic*
S53 TI psychosocial* or AB psychosocial*
S52 TI (motivat* and (interv* or intervent*)) or AB (motivat* and (interv* or intervent*))
S51 TI (psycho‐educat* or psychoeducat*) or AB (psycho‐educat* or psychoeducat*)
S50 TI (goal* and setting) or AB (goal* and setting)
S49 TI hypnotherap* or AB hypnotherap*
S48 TI CBT or AB CBT
S47 TI (manage* and (anxiety or depress*)) or AB (manage* and (anxiety or depress*))
S46 (MH "Anxiety+")
S45 TI meditat* or AB meditat*
S44 (MH "Meditation")
S43 TI (cognitive and therap*) or AB (cognitive and therap*)
S42 TI (stress and manag*) or AB (stress and manag*)
S41 (MH "Stress Management")
S40 TI ((behavior* or behaviour*) and (modify or modificat* or therap* or change)) or AB ((behavior* or behaviour*) and (modify or modificat* or therap* or change))
S39 (MH "Counseling+")
S38 TI (counselling or counseling) or AB (counselling or counseling)
S37 (MH "Relaxation Techniques")
S36 TI relax* or AB relax*
S35 TI (psycholog* and intervent*) or AB (psycholog* and intervent*)
S34 TI psychotherap* or AB psychotherap*
S33 (MH "Psychotherapy+")
S32 S22 OR S31
S31 S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30
S30 TI (acute coronary syndrom*) or AB (acute coronary syndrom*)
S29 TI atherectom* or AB atherectom*
S28 TI (pci or ptca) or AB (pci or ptca)
S27 TI stent* or AB stent*
S26 TI (endoluminal repair*) or AB (endoluminal repair*)
S25 TI ((coronary or arterial) and dilat*) or AB ((coronary or arterial) and dilat*)
S24 TI angioplast* or AB angioplast*
S23 TI (percutaneous coronary and (interven* or revascular*)) or AB (percutaneous coronary and (interven* or revascular*))
S22 S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21
S21 (MH "Angina Pectoris")
S20 (MH "Heart Failure")
S19 (MH "Cardiovascular Diseases")
S18 (MH "Heart Diseases")
S17 (MH "Myocardial Revascularization")
S16
S15 (MH "Cardiac Patients")
S14 (MH "Coronary Disease")
S13 (MH "Coronary Artery Bypass")
S12 (MH "Myocardial Infarction")
S11 (MH "Myocardial Ischemia")
S10 TI (stent* and (heart or cardiac*)) or AB (stent* and (heart or cardiac*))
S9 TI PTCA or AB PTCA
S8 TI CABG or AB CABG
S7 TI cardiac* or AB cardiac*
S6 TI (heart and diseas*) or AB (heart and diseas*)
S5 TI (heart and failure) or AB (heart and failure)
S4 TI angina or AB angina
S3 TI ((myocard* or heart) and infarc*) or AB ((myocard* or heart) and infarc*)
S2 TI coronary or AB coronary
S1 TI ((myocard* or heart) and (ischaemi* or ischemi*)) or AB ((myocard* or heart) and (ischaemi* or ischemi*))
WHO ICTRP
Psychological AND "coronary heart disease"
Psychological AND "coronary artery disease"
Clinicaltrials.gov
Psych* AND "coronary heart disease"
Psych* AND "coronary artery disease"
Appendix 2. Search strategies 2009
The Cochrane Library
#1 MeSH descriptor Myocardial Ischemia explode all trees
#2 (myocard* NEAR isch*mi*)
#3 isch*mi* NEAR heart
#4 MeSH descriptor Coronary Artery Bypass explode all trees
#5 coronary
#6 MeSH descriptor Coronary Disease explode all trees
#7 MeSH descriptor Myocardial Revascularization explode all trees
#8 MeSH descriptor Myocardial Infarction explode all trees
#9 myocard* NEAR infarct*
#10 heart NEAR infarct*
#11 MeSH descriptor Angina Pectoris explode all trees
#12 angina
#13 MeSH descriptor Heart Failure, Congestive explode all trees
#14 heart and (failure or attack)
#15 MeSH descriptor Heart Diseases explode all trees
#16 heart and disease*
#17 myocard*
#18 cardiac*
#19 CABG
#20 PTCA
#21 stent* AND (heart or cardiac*)
#22 MeSH descriptor Heart Bypass, Left explode all trees
#23 MeSH descriptor Heart Bypass, Right explode all trees
#24 (#1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23)
#25 MeSH descriptor Psychotherapy explode all trees
#26 psychotherap*
#27 psycholog* NEAR intervent*
#28 relax*
#29 MeSH descriptor Mind‐Body and Relaxation Techniques explode all trees
#30 MeSH descriptor Counseling explode all trees
#31 counsel*ing
#32 MeSH descriptor Cognitive Therapy explode all trees
#33 MeSH descriptor Behavior Therapy explode all trees
#34 (behavio*r*) NEAR/4 (modif* or therap* or rehab* or change)
#35 MeSH descriptor Stress, Psychological explode all trees
#36 stress NEAR manage*
#37 cognitive* NEAR therap*
#38 MeSH descriptor Meditation explode all trees
#39 meditat*
#40 MeSH descriptor Anxiety, this term only
#41 (manage*) NEAR (anxiety or depres*)
#42 CBT
#43 hypnotherap*
#44 goal NEAR/3 setting
#45 (psycho‐educat*) or (psychoeducat*)
#46 motivat* NEAR interv*
#47 MeSH descriptor Psychopathology explode all trees
#48 psychopathol*
#49 MeSH descriptor Autogenic Training explode all trees
#50 autogenic*
#51 self near (manage* or care or motivat*)
#52 distress*
#53 psychosocial* or psycho‐social
#54 #24 and #53
MEDLINE (Ovid) search date: 6 January 2009
1 exp Myocardial Ischemia/
2 (MYOCARD$4 adj4 (ISCHAEMI$2 or ISCHEMI$2)).tw.
3 exp Coronary Artery Bypass/
4 ((ISCHAEMI$2 or ISCHEMI$2) adj4 HEART).tw.
5 CORONARY.ti,ab.
6 exp Coronary Disease/
7 exp Myocardial Revascularization/
8 exp Myocardial Infarction/
9 (MYOCARD$5 adj4 INFARCT$5).tw.
10 (HEART adj4 INFARCT$5).tw.
11 exp Angina Pectoris/
12 ANGINA.tw.
13 exp Heart Failure/
14 (HEART adj6 Failure).tw.
15 or/1‐14507141
16 exp Heart Diseases/
17 (Heart adj4 disease$2).tw.
18 MYOCARD$5.tw.
19 CARDIAC$2.tw.
20 CABG.tw.
21 PTCA.tw.
22 (STENT$4 and HEART).tw.
23 Heart Bypass, Left/ or Heart Bypass, Right/
24 or/16‐23
25 exp Psychotherapy/
26 PSYCHOTHERAP$2.tw.
27 (PSYCHOLOG$5 adj INTERVENT$5).tw.
28 RELAX$6.tw.
29 exp Relaxation Techniques/ or exp "Mind‐Body and Relaxation Techniques"/
30 exp Counseling/
31 (COUNSELLING or COUNSELING).tw.
32 ((BEHAVIOR$4 or BEHAVIOUR$4) adj4 (MODIFY or MODIFICAT$4 or THERAP$2 or CHANGE)).tw.
33 Stress, Psychological/
34 (STRESS adj4 MANAGEMENT).tw.
35 (COGNITIVE adj4 THERAP$2).tw.
36 MEDITAT$4.tw.
37 ANXIETY.tw.
38 (MANAGE$5 adj2 (ANXIETY or DEPRES$5)).tw.
39 CBT.tw.
40 HYPNOTHERAP$5.tw.
41 (GOAL$2 adj3 SETTING).tw.
42 (PSYCHO‐EDUCAT$5 or PSYCHOEDUCAT$5).tw.
43 (MOTIVAT$5 adj3 (INTERVENTION or INTERV$3)).tw.
44 Psychopathology/
45 PSYCHOPATHOL$4.tw.
46 PSYCHOSOCIAL$4.tw.
47 DISTRESS$4.tw.
48 Health Education/
49 (HEALTH adj2 EDUCATION).tw.
50 (HEART adj MANUAL).tw.
51 Autogenic Training/
52 AUTOGENIC$5.tw.
53 or/25‐52
54 24 or 15
55 53 and 54
56 Randomized controlled trial.pt.
57 randomized controlled trial/
58 (random$ or placebo$).ti,ab,sh.
59 ((singl$ or double$ or triple$ or treble$) and (blind$ or mask$)).tw,sh.
60 or/56‐59
61 "controlled clinical trial".pt.
62 (retraction of publication or retracted publication).pt.
63 61 or 62 or 60
64 63 and 55
65 (ANIMALS not HUMANS).sh.
66 64 not 65
EMBASE 1996 to 2008 week 52
1 Heart Disease/
2 (MYOCARD$4 adj2 (ISCHAEMI$2 or ISCHEMI$2)).tw.
3 ((ISCHAEMI$2 or ISCHEMI$2) adj4 HEART).tw.
4 Coronary Artery Disease/
5 Transluminal Coronary Angioplasty/
6 (CORONARY adj4 (DISEASE$2 or BYPASS$2 or THROMBO$5 or ANGIOPLAST$2)).tw.
7 Heart Infarction/
8 (MYOCARD$4 adj2 INFARCT$5).tw.
9 (HEART adj2 INFARC$5).tw.
10 Heart Muscle Revascularization/
11 Angina Pectoris/
12 ANGINA.tw.
13 (HEART adj2 FAILURE).tw.
14 (HEART adj2 DISEASE$2).tw.
15 CARDIAC$2.tw.
16 CABG.tw.
17 PTCA.tw.
18 (STENT$4 and HEART).ti,ab.
19 Extracorporeal Circulation/
20 or/1‐19
21 Psychotherapy/
22 PSYCHOTHERAP$2.tw.
23 RELAX$6.tw.
24 (PSYCHOLOG$5 adj4 INTERVENT$5).tw.
25 Relaxation Training/
26 exp Counseling/
27 (COUNSELLING or COUNSELING).tw.
28 ((BEHAVIOR$4 or BEHAVIOUR$4) adj4 (MODIFY or MODIFICAT$4 or THERAPY$2 or CHANGE)).mp.
29 Stress Management/
30 ((BEHAVIOR$4 or BEHAVIOUR$4) adj4 (MODIFY or MODIFICAT$4 or THERAPY$2 or CHANGE)).tw.
31 (STRESS adj3 MANAGEMENT).tw.
32 exp Meditation/
33 MEDITAT$5.tw.
34 (MANAGE$5 adj2 (ANXIETY or DEPRES$5)).tw.
35 CBT.tw.
36 HYPNOTHERAP$2.tw.
37 (GOAL$2 adj3 SETTING).tw.
38 (MOTIVAT$5 adj4 INTERVENT$6).tw.
39 Psychosocial Care/
40 Psychosocial Rehabilitation/
41 PSYCHOSOCIAL.tw.
42 Autogenic Training/
43 AUTOGENIC.tw.
44 or/21‐43
45 44 and 20
46 Randomized Controlled Trial/
47 Single Blind Procedure/
48 Double Blind Procedure/
49 Crossover Procedure/
50 46 or 47 or 48 or 49
51 (random$ or factorial$ or crossover$ or placebo$ or (cross adj over) or assign$).ti,ab.
52 ((singl$ or double$ or triple$ or treble$) and (blind$ or mask$)).ti,ab.
53 controlled clinical trial*.ti,ab.
54 53 or 51 or 52 or 50
55 45 and 54
56 (animal$ not human$).sh,hw.
57 55 not 56
PsycINFO 1806 to December week 4 2008
1 (RANDOM$5 or PLACEBO$5).tw.
2 ((DOUBLE$4 or SINGLE$4 or TRIPLE$4) and (BLIND$4 or MASK or SHAM$4 or DUMMY)).tw.
3 RCT.tw.
4 "2000".md.
5 ((retract$4 or withdraw$4) adj (public$4 or article$2)).tw.
6 erratum correction.dt.
7 or/1‐6
8 heart disorders/
9 myocardial infarctions/
10 exp Ischemia/
11 heart surgery/
12 ANGIOPLASTY.tw.
13 (HEART adj BYPASS).mp. [mp=title, abstract, heading word, table of contents, key concepts]
14 CORONARY.tw.
15 (ISCHEMI$3 or ISCHAEMI$3).tw.
16 (MYOCARD$5 adj2 INFARCT$5).ti,ab.
17 (HEART adj2 (INFARC$5 or FAILURE or ATTACK)).tw.
18 ANGINA.tw.
19 (HEART adj6 DISEASE$2).tw.
20 MYOCARD$5.tw.
21 CARDIAC$4.tw.
22 CABG.tw.
23 PTCA.tw.
24 or/8‐23
25 exp Psychotherapy/
26 PSYCHOTHERAP$2.tw.
27 treatment/
28 (PSYCHOLOG$4 adj2 INTERVENT$5).tw.
29 exp Counseling/
30 Coping Behavior/
31 exp Meditation/
32 Autogenic Training/
33 RELAX$6.tw.
34 (COUNSELLING or COUNSELING).tw.
35 ((BEHAVIOUR or BEHAVIOR) adj3 (MODIF$5 or THERAP$5 or REHABILIT$5 or CHANGE)).tw.
36 (STRESS adj2 MANAGE$5).tw.
37 MEDITAT$5.tw.
38 (MANAGE$5 adj2 (ANXIETY or DEPRES$5)).tw.
39 (CBT or (COGNITIV$2 adj2 THERAP$3)).tw.
40 HYPNOTHERAP$3.tw.
41 (PSYCHO‐EDUCAT$6 or PSYCHOEDUCAT$6).tw.
42 (MOTIVAT$5 adj2 INTERVENT$5).tw.
43 (SELF adj2 MANAG$6).tw.
44 AUTOGENIC$3.tw.
45 (GOAL adj2 SETTING).tw.
46 or/25‐45
47 46 and 24
48 7 and 47
CINAHL (OVID database with NLH interface)
Search date: 7 January 2009
1 (((MYOCARD* OR HEART) AND (ISCHAEMI* OR ISCHEMI*))).ti,ab
2 CORONARY.ti,ab
3 (((MYOCARD* OR HEART) AND INFARC*)).ti,ab
4 ANGINA.ti,ab
5 ((HEART AND FAILURE)).ti,ab
6 (HEART AND DISEAS*).ti,ab
7 CARDIAC*.ti,ab
8 CABG.ti,ab
9 PTCA.ti,ab
10 (STENT* AND (HEART OR CARDIAC$4)).ti,ab
11 MYOCARDIAL ISCHEMIA/
12 MYOCARDIAL INFARCTION/
13 CORONARY ARTERY BYPASS/
14 CORONARY DISEASE/
15 CARDIAC PATIENTS/
16 MYOCARDIAL DISEASES/
17 MYOCARDIAL REVASCULARIZATION/
18 HEART DISEASES/
19 CARDIOVASCULAR DISEASES/
20 HEART FAILURE, CONGESTIVE/
21 ANGINA PECTORIS/
22 1 OR 2 OR 3 OR 4 OR 5 OR 6 OR 7 OR 8 OR 9 OR 10 OR 11 OR 12 OR 13 OR 14 OR 15 OR 16 OR 17 OR 18 OR 19 OR 20 OR 21
23 exp PSYCHOTHERAPY/
24 PSYCHOTHERAP*.ti,ab
25 (PSYCHOLOG* AND INTERVENT*).ti,ab
26 RELAX*.ti,ab
27 RELAXATION TECHNIQUES/
28 ((COUNSELLING OR COUNSELING)).ti,ab
29 exp COUNSELING/
30 (((BEHAVIOR* OR BEHAVIOUR*) AND (MODIFY OR MODIFICAT* OR THERAP* OR CHANGE))).ti,ab
31 STRESS MANAGEMENT/
32 (STRESS AND MANAG*).ti,ab
33 (COGNITIVE AND THERAP*).ti,ab
34 exp MEDITATION/
35 MEDITAT*.ti,ab
36 exp ANXIETY/
37 (MANAGE* AND (ANXIETY OR DEPRESS*)).ti,ab
38 CBT.ti,ab
39 HYPNOTHERAP*.ti,ab
40 ((GOAL* AND SETTING)).ti,ab
41 (PSYCHO‐EDUCAT* OR PSYCHOEDUCAT*).ti,ab
43 ((MOTIVAT* NEAR (INTERV* OR INTERVENT*))).ti,ab
44 ((MOTIVAT* AND (INTERV* OR INTERVENT*))).ti,ab
45 PSYCHOSOCIAL*.ti,ab
46 AUTOGENIC*.ti,ab
47 23 OR 24 OR 25 OR 26 OR 27 OR 28 OR 29 OR 30 OR 31 OR 32 OR 33 OR 34 OR 35 OR 36 OR 37 OR 38 OR 39 OR 40 OR 41 OR 43 OR 44 OR 45 OR 46
48 22 AND 47
49 ((SINGL* OR DOUBLE* OR TRIPLE* OR TREBLE*) AND (BLIND* OR MASK*)).ti,ab
50 (RANDOM* OR PLACEBO*).ti,ab
51 CLINICAL TRIALS/
52 (CONTROLLED ADJ CLINICAL ADJ TRIALS).ti,ab
53 49 OR 50 OR 51 OR 52
54 48 AND 53
55 48 [Limit to: (Publication Type Clinical Trial)]
Line 54 was downloaded separately to line 55 to incorporate both the text/thesaurus term filter and the interface filter and then de‐duplicated in RefMan
Appendix 3. Search strategy 2001
CCTR search strategy
MYOCARDIAL‐ISCHEMIA*:ME
CORONARY‐ARTERY‐BYPASS*:ME
(ISCHEMI* near HEART)
(ISCHAEMI* near HEART)
(CORONARY near DISEASE*)
(CORONARY near BYPASS)
(CORONARY near THROMBO*)
(CORONARY near ANGIOPLAST)
(CORONARY near ANGIOPLAST*)
(MYOCARD* near ISCHEMI*)
(MYOCARD* near ISCHAEMI*)
(MYOCARD* near INFARCT*)
(HEART near INFARCT*)
ANGINA
((((((((((((#1 or #2) or #3) or #4) or #5) or #6) or #7) or #8) or #9) or #10) or #11) or #12) or #13) or #14)
REHABILITATION*:ME
REHABILITAT*
PSYCHOTHERAPY*:ME
COUNSELING*:ME
RELAXATION‐TECHNIQUES*:ME
PSYCHOTHERAP*
COUNSELING
COUNSELLING
RELAX*
(BEHAVIOR* near MODIF*)
(BEHAVIOUR* near MODIF*)
(BEHAVIOR* near THERAP*)
(BEHAVIOUR* near THERAP*)
(COGNITIVE* near THERAP*)
(STRESS near MANAGE*)
MEDITATION*:ME
MEDITAT*
ANXIETY:ME
(ANXIETY near MANAGE*)
DISTRESS*
PSYCHOPATHOLOGY*:ME
PSYCHOPATHOL*
AUTOGENIC‐TRAINING*:ME
AUTOGENIC*
HEALTH‐EDUCATION*:ME
(HEALTH near EDUCAT*)
(PATIENT near EDUCAT*)
(SELF near MANAGE*)
PSYCHOEDUCAT*
(((((((((((((((((((((((((((((#15 or #16) or #17) or #18) or #19) or #20) or #21) or #22) or #23) or #24) or #25) or #26) or #27) or #28) or #29) or #30) or #31) or #32) or #33) or #34) or #35) or #36) or #37) or #38) or #39) or #40) or #41) or #42) or #43) or #44)
(#45 and #46)
Flow diagram summarising study selection. N: number of RCT: randomised controlled trial
Methodological quality summary: review authors' judgements about each methodological quality item for each included study.
Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.
Funnel plot: psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation) for total mortality (Analysis 1.1).
Funnel plot: psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation) for revascularisation (coronary artery bypass graft surgery and percutaneous coronary intervention combined) (Analysis 1.3).
Funnel plot: psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation) for non‐fatal myocardial infarction (Analysis 1.4).
Funnel plot: psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation) for depression (Analysis 1.5).
Funnel plot: psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation) for stress (Analysis 1.7).
Funnel plot: psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation) for cardiac mortality (Analysis 1.2).
Funnel plot: psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation) for anxiety (Analysis 1.6).
Comparison 1: Psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation), Outcome 1: Total mortality
Comparison 1: Psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation), Outcome 2: Cardiac mortality
Comparison 1: Psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation), Outcome 3: Revascularisation (coronary artery bypass graft surgery and percutaneous coronary intervention combined)
Comparison 1: Psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation), Outcome 4: Non‐fatal myocardial infarction
Comparison 1: Psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation), Outcome 5: Depression
Comparison 1: Psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation), Outcome 6: Anxiety
Comparison 1: Psychological intervention (alone or with other rehabilitation) versus comparator (usual care or other rehabilitation), Outcome 7: Stress
| Psychological intervention with or without other rehabilitation compared to control (usual care/other rehabilitation) for coronary heart disease (third update) | ||||||
| Patient or population: people with coronary heart disease (third update) Settings: centre or home based (± telephone support) Intervention: psychological intervention ± other rehabilitation Comparison: control (usual care/other rehabilitation) | ||||||
| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect | No of participants | Quality of the evidence | Comments | |
|---|---|---|---|---|---|---|
| Assumed risk | Corresponding risk | |||||
| Control (usual care/other rehabilitation) | Psychological intervention +/‐ other rehabilitation | |||||
| Total mortality | Study population | RR 0.90 | 7776 | ⊕⊕⊕⊝ | ‐ | |
| 91 per 1000 | 82 per 1000 | |||||
| Moderate population | ||||||
| 36 per 1000 | 32 per 1000 | |||||
| Cardiac mortality | Study population | RR 0.79 | 4792 | ⊕⊕⊝⊝ | ‐ | |
| 72 per 1000 | 57 per 1000 | |||||
| Moderate population | ||||||
| 49 per 1000 | 39 per 1000 | |||||
| Non‐fatal MI | Study population | RR 0.82 | 7845 | ⊕⊕⊝⊝ | ‐ | |
| 95 per 1000 | 78 per 1000 | |||||
| Moderate population | ||||||
| 67 per 1000 | 55 per 1000 | |||||
| Revascularisation (CABG and PCI combined) | Study population | RR 0.94 | 6822 | ⊕⊕⊕⊝ | ‐ | |
| 121 per 1000 | 114 per 1000 | |||||
| Moderate population | ||||||
| 115 per 1000 | 108 per 1000 | |||||
| Anxiety | ‐ | The mean anxiety in the intervention groups was | ‐ | 3165 | ⊕⊕⊝⊝ | ‐ |
| Depression | ‐ | The mean depression in the intervention groups was | ‐ | 5829 | ⊕⊕⊝⊝ | ‐ |
| Stress | ‐ | The mean stress in the intervention groups was | ‐ | 1255 | ⊕⊝⊝⊝ | ‐ |
| *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). | ||||||
| GRADE Working Group grades of evidence | ||||||
| 1 Random sequence generation, allocation concealment, or blinding of outcome assessors were poorly described in 50% or more of included studies. | ||||||
| Trial | Follow‐up (months) | Measure | Scores at follow‐up: intervention vs comparator, P value | Between‐group difference |
|---|---|---|---|---|
| Depression | ||||
| 18 | Depression (clinical diagnosis, DSM‐IV criteria) | Odds of being depressed, controlling for age, gender, and baseline depression OR 0.50 (95% CI 0.26 to 0.95), P = 0.04 | Intervention > comparator | |
| 9 | Beck Depression Inventory | Mean (SD): CBT 6.7 (8.32); SSM 9.9 (9.07) vs 12.9 (9.29), P < 0.001 | Intervention > comparator | |
| 12 | Hamilton Anxiety and Depression Combined Score | Median (IQR): 6 (2 to 9) vs 7 (4 to 11.5); mean difference ‐2.35 (SD NR), P = NS | Intervention ≈ comparator | |
| 6 | Patient Health Questionnaire ‐ 9 | Mean (SD): 6.1 (5.5) vs 8.1 (5.8), P = NS | Intervention ≈ comparator | |
| 18 | Beck Depression Inventory (diagnosis) | OR 0.31 (95% CI 0.16 to 0.61) vs 1.15 (95% CI 0.60 to 0.22), P = 0.009 | Intervention > comparator | |
| Distress | ||||
| 18 | Symptom Checklist‐25 | OR 0.4 (95% CI 0.21 to 0.84) vs 0.9 (95% CI 0.43 to 1.86), P = NS | Intervention ≈ comparator | |
| Anger | ||||
| 12 | Anger (STAXI): State | Mean (SD): 10.9 (2.3) vs 11.1 (2.6), P = NS | Intervention ≈ comparator | |
| 12 | Anger (STAXI): Trait | Mean (SD): 17.4 (4.2) vs 18 (4.8), P = NS | Intervention ≈ comparator | |
| 12 | Anger (STAXI): In | Mean (SD): 17.1 (4.7) vs 16.8 (4.9), P = NS | Intervention ≈ comparator | |
| 12 | Anger (STAXI): Out | Mean (SD): 11.6 (2.7) vs 11.5 (3.1), P = NS | Intervention ≈ comparator | |
| 12 | Anger (STAXI): Control | Mean (SD): 24.5 (4.2) vs 24.4 (4.5), P = NS | Intervention ≈ comparator | |
| Type A behaviour | ||||
| 54 | Type A: Videotaped Clinical Interview for Type A behaviour | Mean (SD): 15.5 (8.9) vs 22.1 (9.7), P < 0.001 | Intervention > comparator | |
| 9 | Type A: Revised Videotaped Structured Interview (Hostility subscale) | Mean (SD): 53.6 (25.3) vs 58.9 (29.5), P = 0.03 | Intervention > comparator | |
| 9 | Type A: Revised Videotaped Structured Interview (Time Urgency subscale) | Mean (SD): 66.5 (29.6) vs 75 (32.1), P = 0.01 | Intervention > comparator | |
| 9 | Type A: Revised Videotaped Structured Interview (Insecurity subscale) | Mean (SD): 25.8 (20.6) vs 26.3 (22.6), P = NS | Intervention ≈ comparator | |
| Vital exhaustion | ||||
| 9 | Maastricht Questionnaire | Mean (SD): 4.6 (5.7) vs 4.7 (5.5), P = NS | Intervention ≈ comparator | |
| 12 | Mean (SD): 12.2 (17.3) vs 15.8 (19.4), P < 0.05 | Intervention > comparator | ||
| 30 | Mean (SD): 16.5 (11.1) vs 16.9 (11.3), P = 0.005 | Intervention > comparatora | ||
| 23 | Mean (SD): 56.5 (8.1) vs 59.7 (14.5), P = NS | Intervention ≈ comparator | ||
| Hopelessness | ||||
| 9 | Beck Hopelessness Scale | Mean (SD): CBT 3.5 (5.1); SSM 5.5 (5.8) vs 7.5 (6.0), P = NS | Intervention ≈ comparator | |
| a The authors noted in their discussion that "due to regression towards the mean we cannot attribute the decrease in vital exhaustion to the intervention." CBT: cognitive behavioural therapy; CI: confidence interval; DSM‐IV: Diagnostic and Statistical Manual of Mental Disorders ‐ 4th edition; IQR: interquartile range; OR: odds ratio; NR: not reported; NS: non‐significant (P >0.10); SD: standard deviation; SSM: supportive stress management; STAXI: Spielberger Anger scales (STAXI 1985). | ||||
| Trial | Follow‐up (months) | Measure | Scores at follow‐up (mean (SD)): intervention vs comparator, P value | Between‐group differencea |
|---|---|---|---|---|
| 18 | MacNew Questionnaire: Global Score | 126.9 (27.4) vs 127.1 (25.8), P = NS | Intervention ≈ comparator | |
| 12 | Swedish Quality of Life Scale | 6.59 (2.95) vs 5.97 (3.15), P = NS | Intervention ≈ comparator | |
| 6 | SF‐12: Physical Component Score | 0.8 (23.0), P = NSb | Intervention ≈ comparator | |
| 6 | SF‐12: Mental Component Score | 2.2 (18.3), P < 0.05b | Intervention > comparator | |
| 6 | Life Satisfaction Scale | 1.0 (9.8), P < 0.05b | Intervention > comparator | |
| 6 | Ladder of Life | 0.3 (4.6), P < 0.05b | Intervention > comparator | |
| 9 | SF‐36: Physical Component Score | CBT 37.6 (9.6); SSM 38.9 (9.7) vs 36.9 (10.6), P = NS | Intervention ≈ comparator | |
| 9 | SF‐36 Mental Component Score | CBT 49.1 (12.2); SSM 47.8 (13.0) vs 42.4 (13.3), P = 0.01 | Intervention > comparator | |
| 6 | SAQ: Physical Limitations | 86.4 (15.6) vs 83.2 (18.7), P = NS | Intervention ≈ comparator | |
| 6 | SAQ: Angina Frequency | 91.7 (16.6) vs 90.8 (18.9), P = NS | Intervention ≈ comparator | |
| 6 | SAQ: Treatment Satisfaction | 89.2 (15.4) vs 88.0 (16.1), P = NS | Intervention ≈ comparator | |
| 6 | SAQ: Disease Perception | 77.8 (20.2) vs 3.9 (24.2), P = NS | Intervention ≈ comparator | |
| 6 | SF‐36: Physical Component Score | 47.4 (9.6) vs 47.0 (10.0), P = NS | Intervention ≈ comparator | |
| 6 | SF‐36: Mental Component Score | 52.1 (10.7) vs 50.5 (10.8), P = NS | Intervention ≈ comparator | |
| 12 | Dartmouth COOP | 14 (IQR 13 to 17) vs 15 (IQR 12.5 to 21), P = NSc | Intervention ≈ comparator | |
| 12 | SF‐36: Physical Component Score | 43.2 (9.2) vs 46.1 (9.3), P = NS | Intervention ≈ comparator | |
| 12 | SF‐36: Mental Component Score | 47.2 (9.2) vs 49.3 (10), P = NS | Intervention ≈ comparator | |
| 12 | SF‐12: Physical Component Score | 36.6 (10.5) vs 36.2 (10.5), P = NR | Intervention ≈ comparator | |
| 12 | SF‐12: Mental Component Score | 45.6 (9.3) vs 42.7 (11.1), P = NR | Intervention ≈ comparator | |
| 30 | SF‐36: Physical Component Score | 64.3 (5.2) vs 61.7 (4.8), P = 0.04 | Intervention > comparator | |
| 30 | SF‐36: Mental Component Score | 58.9 (5.9) vs 53.0 (2.2), P < 0.01 | Intervention > comparator | |
| 12 | MacNew Questionnaire: Global Score | 6.07 (IQR 5.48 to 6.39) vs 5.67 (IQR 4.89 to 6.31), P = 0.07c | Intervention ≈ comparator | |
| 12 | MacNew Questionnaire: Emotional Score | 5.79 (IQR 5.36 to 6.35) vs 5.79 (IQR 5.0 to 6.32), P = NSc | Intervention ≈ comparator | |
| 12 | MacNew Questionnaire: Physical Score | 6.23 (IQR 5.70 to 6.53) vs 5.69 (IQR 4.85 to 6.29), P = 0.03c | Intervention > comparator | |
| 12 | MacNew Questionnaire: Social Score | 6.15 (IQR 5.69 to 6.61) vs 5.86 (IQR 5.0 to 6.46), P = 0.06c | Intervention ≈ comparator | |
| a Intervention ≈ comparator (intervention and comparator equivalent); intervention > comparator (intervention superior to comparator group). b Mean difference (SD). c Median (IQR) and P value from Mann Whitney U test. CBT: cognitive behavioural therapy; NS: non‐significant (P > 0.10); SAQ: Seattle Angina Questionnaire; SD: standard deviation; SF‐12: 12‐item Short Form; SF‐36: 36‐item Short Form; SSM: supportive stress management. | ||||
| Predictor | Total mortality | Explanatory variable codinga |
|---|---|---|
| Population targeted at baseline | ||
| Psychological disorder present | 1.19 (0.18), P = 0.26 | Non‐selected 0, present 1 |
| Characteristics of psychological intervention | ||
| Mode of treatment | 1.21 (0.18), P = 0.21 | Individual 0, group 1, both 2 |
| Family included | 1.11 (0.19), P = 0.55 | No 0, yes 1 |
| CRF education included | 0.92 (0.14), P = 0.58 | No 0, yes 1 |
| Intervention targeted behavioural change of CRFs | 1.06 (0.16), P = 0.72 | No 0, yes 1 |
| Psychological treatment targets | ||
| Depression | 1.28 (0.25), P = 0.22 | No 0, yes 1 |
| Anxiety | 1.22 (0.23), P = 0.31 | No 0, yes 1 |
| Stress | 1.28 (0.39), P = 0.43 | No 0, yes 1 |
| Type A behaviour | 0.98 (0.15), P = 0.89 | No 0, yes 1 |
| Psychological components | ||
| Relaxation training | 1.15 (0.22), P = 0.47 | No 0, yes 1 |
| Stress management techniques | 1.15 (0.25), P = 0.54 | No 0, yes 1 |
| Cognitive challenge/restructuring techniques | 1.10 (0.17), P = 0.53 | No 0, yes 1 |
| Emotional support or client‐led discussion, or both | 1.42 (0.25), P = 0.07 | No 0, yes 1 |
| Adjunct pharmacology | 2.08 (2.53), P = 0.56 | No 0, yes 1 |
| a If relevant information was not reported the study was coded as 0. CRF: cardiac risk factor; SE: standard error. | ||
| Predictor | Cardiac‐mortality | Explanatory variable codinga |
|---|---|---|
| Population targeted at baseline | ||
| Psychological disorder present | 1.17 (0.30), P = 0.58 | Non‐selected 0, present 1 |
| Characteristics of psychological intervention | ||
| Mode of treatment | 1.19 (0.32), P = 0.56 | Individual 0, group 1, both 2 |
| Family includedb | 0.82 (0.09), P = 0.13 | No 0, yes 1 |
| CRF education included | 0.84 (0.24), P = 0.57 | No 0, yes 1 |
| Intervention targeted behavioural change of CRFs | 1.17 (0.49), P = 0.72 | No 0, yes 1 |
| Psychological treatment targets | ||
| Depression | 1.13 (0.31), P = 0.67 | No 0, yes 1 |
| Anxiety | 1.13 (0.31), P = 0.67 | No 0, yes 1 |
| Stress | 1.24 (0.71), P = 0.72 | No 0, yes 1 |
| Type A behaviour | 1.02 (0.46), P = 0.95 | No 0, yes 1 |
| Psychological components | ||
| Relaxation training | 1.27 (0.74), P = 0.70 | No 0, yes 1 |
| Stress management techniques | 1.03 (0.46), P = 0.95 | No 0, yes 1 |
| Cognitive challenge/restructuring techniques | 1.11 (0.40), P = 0.78 | No 0, yes 1 |
| Emotional support or client‐led discussion, or both | 1.16 (0.30), P = 0.58 | No 0, yes 1 |
| Adjunct pharmacologyb | 0.82 (0.9), P = 0.13 | No 0, yes 1 |
| a If relevant information was not reported the variable/study was coded as 0. b 'Yes' category (coded 1) contained no participants. Data reported from a model including 'no' (coded 0) only. CRF: cardiac risk factor; SE: standard error. | ||
| Predictor | Depression | Explanatory variable codinga |
|---|---|---|
| Population targeted at baseline | ||
| Psychological disorder present | ‐0.20 (0.12), P = 0.10 | Non‐selected 0, present 1 |
| Characteristics of psychological intervention | ||
| Mode of treatment | 0.007 (0.09), P = 0.94 | Individual 0, group 1, both 2 |
| Family included | 0.06 (0.14), P = 0.70 | No 0, yes 1 |
| CRF education included | 0.06 (0.13), P = 0.65 | No 0, yes 1 |
| Intervention targeted behavioural change of CRFs | ‐0.16 (0.12), P = 0.20 | No 0, yes 1 |
| Psychological treatment targets | ||
| Depression | 0.15 (0.13), P = 0.26 | No 0, yes 1 |
| Anxiety | 0.18 (0.12), P = 0.17 | No 0, yes 1 |
| Stress | 0.13 (0.13), P = 0.35 | No 0, yes 1 |
| Type A behaviour | ‐0.65 (0.14), P = 0.65 | No 0, yes 1 |
| Psychological components | ||
| Relaxation training | ‐0.09 (0.13), P = 0.50 | No 0, yes 1 |
| Stress management techniques | 0.09 (0.13), P = 0.52 | No 0, yes 1 |
| Cognitive challenge/restructuring techniques | 0.07 (0.14), P = 0.59 | No 0, yes 1 |
| Emotional support or client‐led discussion, or both | 0.14 (0.13), P = 0.28 | No 0, yes 1 |
| Adjunct pharmacology | ‐0.51 (0.15), P = 0.003 | No 0, yes 1 |
| a If relevant information was not reported the variable/study was coded as 0. CRF: cardiac risk factor; SE: standard error. | ||
| Predictor | Anxiety | Explanatory variable codinga |
|---|---|---|
| Population targeted at baseline | ||
| Psychological disorder present | ‐0.28 (0.11), P = 0.03 | Non‐selected 0, present 1 |
| Characteristics of psychological intervention | ||
| Mode of treatment | 0.09 (0.09), P = 0.30 | Individual 0, group 1, both 2 |
| Family included | 0.24 (0.12), P = 0.06 | No 0, yes 1 |
| CRF education included | 0.18 (0.13), P = 0.21 | No 0, yes 1 |
| Intervention targeted behavioural change of CRFs | ‐0.08 (0.17), P = 0.61 | No 0, yes 1 |
| Psychological treatment targets | ||
| Depression | ‐0.04 (0.16), P = 0.83 | No 0, yes 1 |
| Anxiety | 0.05 (0.15), P = 0.78 | No 0, yes 1 |
| Stress | 0.18 (0.13), P = 0.20 | No 0, yes 1 |
| Type A behaviour | ‐01 (0.26), P = 0.97 | No 0, yes 1 |
| Psychological components | ||
| Relaxation training | 0.15 (0.14), P = 0.29 | No 0, yes 1 |
| Stress management techniques | ‐0.03 (0.15), P = 0.87 | No 0, yes 1 |
| Cognitive challenge/restructuring techniques | ‐0.16 (0.14), P = 0.29 | No 0, yes 1 |
| Emotional support or client‐led discussion, or both | 0.12 (0.14), P = 0.44 | No 0, yes 1 |
| Adjunct pharmacology | ‐0.12 (0.24), P = 0.65 | No 0, yes 1 |
| a If relevant information was not reported the variable/study was coded as 0. CRF: cardiac risk factor; SE: standard error. | ||
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1.1 Total mortality Show forest plot | 23 | 7776 | Risk Ratio (M‐H, Random, 95% CI) | 0.90 [0.77, 1.05] |
| 1.2 Cardiac mortality Show forest plot | 11 | 4792 | Risk Ratio (M‐H, Random, 95% CI) | 0.79 [0.63, 0.98] |
| 1.3 Revascularisation (coronary artery bypass graft surgery and percutaneous coronary intervention combined) Show forest plot | 13 | 6822 | Risk Ratio (M‐H, Random, 95% CI) | 0.94 [0.81, 1.11] |
| 1.4 Non‐fatal myocardial infarction Show forest plot | 13 | 7845 | Risk Ratio (M‐H, Random, 95% CI) | 0.82 [0.64, 1.05] |
| 1.5 Depression Show forest plot | 19 | 5825 | Std. Mean Difference (IV, Random, 95% CI) | ‐0.27 [‐0.39, ‐0.15] |
| 1.6 Anxiety Show forest plot | 12 | 3161 | Std. Mean Difference (IV, Random, 95% CI) | ‐0.24 [‐0.38, ‐0.09] |
| 1.7 Stress Show forest plot | 8 | 1251 | Std. Mean Difference (IV, Random, 95% CI) | ‐0.56 [‐0.88, ‐0.24] |
