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Cochrane Database of Systematic Reviews

Inmunoterapia sublingual para la rinitis alérgica

Información

DOI:
https://doi.org/10.1002/14651858.CD002893.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 08 diciembre 2010see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:

  1. Grupo Cochrane de Enfermedades de oído, nariz y garganta

Copyright:
  1. Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Autores

  • Suzana Radulovic

    Correspondencia a: LEAP Study Team, Paediatric Allergy Research Department, King's College, London, UK

    [email protected]

    [email protected]

  • Moises A Calderon

    Department of Allergy and Respiratory Medicine, Royal Brompton Hospital, London, UK

  • Duncan Wilson

    Selly Oak Hospital, University Hospitals Birmingham NHS Trust, Birmingham, UK

  • Stephen Durham

    Department of Allergy and Respiratory Medicine, Royal Brompton Hospital, London, UK

Contributions of authors

SUZANA RADULOVIC: Lead review author, searching for trials, quality assessment of trials, design of data extraction form, data extraction, data analysis.

MOISES CALDERON: Review author, searching for trials, quality assessment of trials, data analysis, input at all other stages of review.

DUNCAN WILSON: Review author, protocol development, quality assessment of trials, design of data extraction form, data extraction, data analysis.

STEPHEN DURHAM: Protocol development, input at all other stages of review.

Declarations of interest

The lead review author, Dr Suzana Radulovic, has received financial support from the ITN (Immune Tolerance Network) as an employee of the Paediatric Allergy Research Department at King's College London, UK.

The Department of Upper Respiratory Medicine, National Heart & Lung Institute, London, UK, headed by Professor Durham, has received financial support from ALK Abello, Horsholm, Denmark ‐ manufacturers of allergen extracts. Stephen Durham has received consultancy and lecture fees and research grants from Alk Abello, a manufacturer of allergy vaccines, via Imperial College.

There are no other conflicts of interest to be declared.

Acknowledgements

Grateful thanks are extended to the authors of individual studies who provided additional data to allow meaningful meta‐analysis to be performed.

Version history

Published

Title

Stage

Authors

Version

2010 Dec 08

Sublingual immunotherapy for allergic rhinitis

Review

Suzana Radulovic, Moises A Calderon, Duncan Wilson, Stephen Durham

https://doi.org/10.1002/14651858.CD002893.pub2

2003 Apr 22

Sublingual immunotherapy for allergic rhinitis

Review

Duncan Wilson, Marcia Torres‐Lima, Stephen Durham

https://doi.org/10.1002/14651858.CD002893

Differences between protocol and review

  1. Evaluation of safety has been noted as a primary objective of the review.

  2. The I² statistic has now been used to quantify heterogeneity.

  3. The Cochrane 'Risk of bias' tool has now been used to assess the methodological quality of the included trials.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.