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Cochrane Database of Systematic Reviews

کاستینگ (مهار کردن گنادوتروپین‌ها) به منظور پیشگیری از سندرم تحریک بیش از حد تخمدان

Información

DOI:
https://doi.org/10.1002/14651858.CD002811.pub4Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 23 mayo 2017see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Ginecología y fertilidad

Copyright:
  1. Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Contraer

Autores

  • Arianna D'Angelo

    Correspondencia a: Obstetrics and Gynaecology, Cardiff University School of Medicine, Cardiff, UK

    [email protected]

    [email protected]

  • Nazar N Amso

    Emeritus Professor, Cardiff University School of Medicine, Cardiff, UK

  • Rudaina Hassan

    Wales Deanery, Cardiff University, Cardiff, UK

Contributions of authors

Arianna D'Angelo took the lead in writing the protocol and review, performed searches of databases and contacted journals for trials, performed independent data extraction and quality assessment of the included trials, and was responsible for statistical analysis and interpretation of the data.
Nazar Amso assisted in writing the protocol and the final manuscript of the review, was involved in selecting trials for the review, and performed independent data extraction and quality assessment of the included trials.

Dr Julie Brown assisted with the update of the review in 2010, with the data analysis, interpretation and writing.

Dr Rudaina Hassan assisted in the update of the review in 2016, with data analysis, interpretation and writing.

Sources of support

Internal sources

  • Department of Obstetrics & Gynaecology, University Hospital of Wales, UK.

External sources

  • None, Other.

Declarations of interest

ADA, NNA and RH have no conflicts of interest to declare

Acknowledgements

The authors wish to thank the Cochrane Gynaecology and Fertility Group editorial office staff for their advice and support through the review process.

We thank also Dr Julie Brown for her contributions to previous versions of this review.

Version history

Published

Title

Stage

Authors

Version

2017 May 23

Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome

Review

Arianna D'Angelo, Nazar N Amso, Rudaina Hassan

https://doi.org/10.1002/14651858.CD002811.pub4

2011 Jun 15

Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome

Review

Arianna D'Angelo, Julie Brown, Nazar N Amso

https://doi.org/10.1002/14651858.CD002811.pub3

2011 Feb 16

Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome

Review

Arianna D'Angelo, Julie Brown, Nazar N Amso

https://doi.org/10.1002/14651858.CD002811.pub2

2002 Jul 22

Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome

Review

Arianna D'Angelo, Nazar N Amso, Julie Brown

https://doi.org/10.1002/14651858.CD002811

Differences between protocol and review

The number of embryos transferred was removed as an outcome in the 2010 update. It was not a measure of the treatment effect as the number of embryos transferred is subject to external regulation.

The number of patients admitted to hospital was removed as an outcome in the 2017 update, as this is not a measure of the treatment effect, since management protocols for OHSS may vary in different centres. The number of days to next menstrual period was removed as an outcome in the 2017 update, as this is not a measure of the severity of OHSS. The miscarriage rate was added as an outcome in 2017, as it is a relevant clinical outcome. Multiple pregnancy rate and miscarriage rate were analyzed both per woman randomised and per pregnancy in this update, to explore whether our findings were sensitive to the choice of analysis.

We amended the inclusion criteria for participants, as it was previously unclear whether only women with PCOS were eligible: we have clarified that women with PCOS are eligible, but the review was not restricted to women with PCOS

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.