Medical adjuvant treatment to increase patency of arteriovenous fistulae and grafts

Gary Osborn; Xavier Escofet; Anthony Da Silva

doi:10.1002/14651858.CD002786.pub2

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Analysis 1.1

Comparison 1 Aspirin versus placebo, Outcome 1 Graft thrombosis.

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Analysis 2.1

Comparison 2 Ticlopidine versus placebo, Outcome 1 Fistulae thromboses at one month.

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Analysis 3.1

Comparison 3 Dipyridamole versus placebo, Outcome 1 Graft thrombosis.

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Analysis 4.1

Comparison 4 Dipyridamole + aspirin versus placebo, Outcome 1 Graft thrombosis.

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Analysis 5.1

Comparison 5 Warfarin versus placebo, Outcome 1 Graft thrombosis.

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Analysis 6.1

Comparison 6 Fish oil versus placebo, Outcome 1 Graft thrombosis.

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Analysis 7.1

Comparison 7 Clopidogrel versus placebo, Outcome 1 Graft thrombosis.

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Analysis 8.1

Comparison 8 Sulfinpyrazone (SF) versus placebo, Outcome 1 Graft thrombosis.

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Comparison 1. Aspirin versus placebo

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Graft thrombosis Show forest plot	3	173	Odds Ratio (M‐H, Fixed, 95% CI)	0.42 [0.20, 0.86]

Comparison 1. Aspirin versus placebo

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Comparison 2. Ticlopidine versus placebo

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Fistulae thromboses at one month Show forest plot	3	312	Odds Ratio (M‐H, Fixed, 95% CI)	0.47 [0.26, 0.85]

Comparison 2. Ticlopidine versus placebo

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Comparison 3. Dipyridamole versus placebo

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Graft thrombosis Show forest plot	1		Odds Ratio (M‐H, Fixed, 95% CI)	Totals not selected

Comparison 3. Dipyridamole versus placebo

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Comparison 4. Dipyridamole + aspirin versus placebo

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Graft thrombosis Show forest plot	1		Odds Ratio (M‐H, Fixed, 95% CI)	Totals not selected

Comparison 4. Dipyridamole + aspirin versus placebo

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Comparison 5. Warfarin versus placebo

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Graft thrombosis Show forest plot	1		Odds Ratio (M‐H, Fixed, 95% CI)	Totals not selected

Comparison 5. Warfarin versus placebo

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Comparison 6. Fish oil versus placebo

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Graft thrombosis Show forest plot	1		Odds Ratio (M‐H, Fixed, 95% CI)	Totals not selected

Comparison 6. Fish oil versus placebo

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Comparison 7. Clopidogrel versus placebo

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Graft thrombosis Show forest plot	1		Odds Ratio (M‐H, Fixed, 95% CI)	Totals not selected

Comparison 7. Clopidogrel versus placebo

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Comparison 8. Sulfinpyrazone (SF) versus placebo

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Graft thrombosis Show forest plot	1		Odds Ratio (M‐H, Fixed, 95% CI)	Totals not selected

Comparison 8. Sulfinpyrazone (SF) versus placebo

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