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'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.
Figuras y tablas -
Figure 1

'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.

'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
Figuras y tablas -
Figure 2

'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.

Comparison 1 Hydrocolloid dressing vs chlorhexidine‐impregnated gauze dressing, Outcome 1 Withdrawal due to wound infection.
Figuras y tablas -
Analysis 1.1

Comparison 1 Hydrocolloid dressing vs chlorhexidine‐impregnated gauze dressing, Outcome 1 Withdrawal due to wound infection.

Comparison 2 Hydrocolloid dressing vs silver sulphadiazine, Outcome 1 Number of dressing changes.
Figuras y tablas -
Analysis 2.1

Comparison 2 Hydrocolloid dressing vs silver sulphadiazine, Outcome 1 Number of dressing changes.

Comparison 2 Hydrocolloid dressing vs silver sulphadiazine, Outcome 2 Level of pain.
Figuras y tablas -
Analysis 2.2

Comparison 2 Hydrocolloid dressing vs silver sulphadiazine, Outcome 2 Level of pain.

Comparison 3 Polyurethane film dressing vs paraffin gauze dressing, Outcome 1 Wound infection.
Figuras y tablas -
Analysis 3.1

Comparison 3 Polyurethane film dressing vs paraffin gauze dressing, Outcome 1 Wound infection.

Comparison 4 Polyurethane film dressing vs chlorhexidine‐impregnated paraffin gauze dressing, Outcome 1 Wound infection.
Figuras y tablas -
Analysis 4.1

Comparison 4 Polyurethane film dressing vs chlorhexidine‐impregnated paraffin gauze dressing, Outcome 1 Wound infection.

Comparison 5 Hydrogel dressing vs usual care, Outcome 1 Wound healing: number of people healed at 6 days.
Figuras y tablas -
Analysis 5.1

Comparison 5 Hydrogel dressing vs usual care, Outcome 1 Wound healing: number of people healed at 6 days.

Comparison 5 Hydrogel dressing vs usual care, Outcome 2 Wound healing: number of people healed at 9 days.
Figuras y tablas -
Analysis 5.2

Comparison 5 Hydrogel dressing vs usual care, Outcome 2 Wound healing: number of people healed at 9 days.

Comparison 5 Hydrogel dressing vs usual care, Outcome 3 Wound healing: number of people healed at 21 days.
Figuras y tablas -
Analysis 5.3

Comparison 5 Hydrogel dressing vs usual care, Outcome 3 Wound healing: number of people healed at 21 days.

Comparison 5 Hydrogel dressing vs usual care, Outcome 4 Wound healing: number of people healed at 12 days.
Figuras y tablas -
Analysis 5.4

Comparison 5 Hydrogel dressing vs usual care, Outcome 4 Wound healing: number of people healed at 12 days.

Comparison 5 Hydrogel dressing vs usual care, Outcome 5 Wound healing: number of people healed at 15 days.
Figuras y tablas -
Analysis 5.5

Comparison 5 Hydrogel dressing vs usual care, Outcome 5 Wound healing: number of people healed at 15 days.

Comparison 5 Hydrogel dressing vs usual care, Outcome 6 Wound healing: number of people healed at 18 days.
Figuras y tablas -
Analysis 5.6

Comparison 5 Hydrogel dressing vs usual care, Outcome 6 Wound healing: number of people healed at 18 days.

Comparison 5 Hydrogel dressing vs usual care, Outcome 7 Assessment of pain at baseline.
Figuras y tablas -
Analysis 5.7

Comparison 5 Hydrogel dressing vs usual care, Outcome 7 Assessment of pain at baseline.

Comparison 5 Hydrogel dressing vs usual care, Outcome 8 Pain 30 minutes after treatment.
Figuras y tablas -
Analysis 5.8

Comparison 5 Hydrogel dressing vs usual care, Outcome 8 Pain 30 minutes after treatment.

Comparison 5 Hydrogel dressing vs usual care, Outcome 9 Overall assessment of pain at end of study.
Figuras y tablas -
Analysis 5.9

Comparison 5 Hydrogel dressing vs usual care, Outcome 9 Overall assessment of pain at end of study.

Comparison 5 Hydrogel dressing vs usual care, Outcome 10 Infection with Pseudomonas aeruginosa requiring antibiotic therapy.
Figuras y tablas -
Analysis 5.10

Comparison 5 Hydrogel dressing vs usual care, Outcome 10 Infection with Pseudomonas aeruginosa requiring antibiotic therapy.

Comparison 6 Silicon nylon dressing vs silver sulphadiazine, Outcome 1 Number of dressing changes.
Figuras y tablas -
Analysis 6.1

Comparison 6 Silicon nylon dressing vs silver sulphadiazine, Outcome 1 Number of dressing changes.

Comparison 7 Biosynthetic skin substitute (Biobrane) vs silver sulphadiazine, Outcome 1 Pain.
Figuras y tablas -
Analysis 7.1

Comparison 7 Biosynthetic skin substitute (Biobrane) vs silver sulphadiazine, Outcome 1 Pain.

Comparison 7 Biosynthetic skin substitute (Biobrane) vs silver sulphadiazine, Outcome 2 Need for surgery.
Figuras y tablas -
Analysis 7.2

Comparison 7 Biosynthetic skin substitute (Biobrane) vs silver sulphadiazine, Outcome 2 Need for surgery.

Comparison 8 Antimicrobial‐releasing biosynthetic dressings vs silver sulphadiazine, Outcome 1 Wound infection.
Figuras y tablas -
Analysis 8.1

Comparison 8 Antimicrobial‐releasing biosynthetic dressings vs silver sulphadiazine, Outcome 1 Wound infection.

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 1 Wound healing time (days).
Figuras y tablas -
Analysis 9.1

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 1 Wound healing time (days).

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 2 Wound healing: number of people healed at 7 days.
Figuras y tablas -
Analysis 9.2

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 2 Wound healing: number of people healed at 7 days.

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 3 Wound healing: number of people healed at 10 days.
Figuras y tablas -
Analysis 9.3

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 3 Wound healing: number of people healed at 10 days.

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 4 Wound healing: number of people healed at 15 days.
Figuras y tablas -
Analysis 9.4

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 4 Wound healing: number of people healed at 15 days.

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 5 Wound healing: number of people healed at 17 days.
Figuras y tablas -
Analysis 9.5

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 5 Wound healing: number of people healed at 17 days.

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 6 Wound healing: number of people healed at 21 days.
Figuras y tablas -
Analysis 9.6

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 6 Wound healing: number of people healed at 21 days.

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 7 Healing rate (% wound area).
Figuras y tablas -
Analysis 9.7

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 7 Healing rate (% wound area).

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 8 Pain.
Figuras y tablas -
Analysis 9.8

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 8 Pain.

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 9 Need for surgery.
Figuras y tablas -
Analysis 9.9

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 9 Need for surgery.

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 10 Number of infections.
Figuras y tablas -
Analysis 9.10

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 10 Number of infections.

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 11 Number of wound dressings.
Figuras y tablas -
Analysis 9.11

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 11 Number of wound dressings.

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 12 Nursing time (minutes).
Figuras y tablas -
Analysis 9.12

Comparison 9 Silver‐impregnated dressing vs silver sulphadiazine, Outcome 12 Nursing time (minutes).

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 1 Wound healing time (days).
Figuras y tablas -
Analysis 10.1

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 1 Wound healing time (days).

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 2 Pain at day 1.
Figuras y tablas -
Analysis 10.2

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 2 Pain at day 1.

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 3 Pain at day 3.
Figuras y tablas -
Analysis 10.3

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 3 Pain at day 3.

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 4 Pain at day 7.
Figuras y tablas -
Analysis 10.4

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 4 Pain at day 7.

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 5 Number of dressing changes.
Figuras y tablas -
Analysis 10.5

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 5 Number of dressing changes.

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 6 Number of infections.
Figuras y tablas -
Analysis 10.6

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 6 Number of infections.

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 7 Need for surgery.
Figuras y tablas -
Analysis 10.7

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 7 Need for surgery.

Comparison 1. Hydrocolloid dressing vs chlorhexidine‐impregnated gauze dressing

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Withdrawal due to wound infection Show forest plot

1

68

Risk Ratio (M‐H, Fixed, 95% CI)

2.53 [0.11, 59.90]

Figuras y tablas -
Comparison 1. Hydrocolloid dressing vs chlorhexidine‐impregnated gauze dressing
Comparison 2. Hydrocolloid dressing vs silver sulphadiazine

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Number of dressing changes Show forest plot

1

42

Mean Difference (IV, Fixed, 95% CI)

‐18.65 [‐22.54, ‐14.76]

2 Level of pain Show forest plot

1

42

Mean Difference (IV, Fixed, 95% CI)

‐1.19 [‐1.82, ‐0.56]

Figuras y tablas -
Comparison 2. Hydrocolloid dressing vs silver sulphadiazine
Comparison 3. Polyurethane film dressing vs paraffin gauze dressing

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Wound infection Show forest plot

1

55

Risk Ratio (M‐H, Fixed, 95% CI)

1.25 [0.23, 6.90]

Figuras y tablas -
Comparison 3. Polyurethane film dressing vs paraffin gauze dressing
Comparison 4. Polyurethane film dressing vs chlorhexidine‐impregnated paraffin gauze dressing

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Wound infection Show forest plot

1

51

Risk Ratio (M‐H, Fixed, 95% CI)

0.48 [0.05, 4.98]

Figuras y tablas -
Comparison 4. Polyurethane film dressing vs chlorhexidine‐impregnated paraffin gauze dressing
Comparison 5. Hydrogel dressing vs usual care

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Wound healing: number of people healed at 6 days Show forest plot

1

80

Risk Ratio (M‐H, Fixed, 95% CI)

1.5 [0.46, 4.91]

2 Wound healing: number of people healed at 9 days Show forest plot

1

80

Risk Ratio (M‐H, Fixed, 95% CI)

2.0 [1.08, 3.72]

3 Wound healing: number of people healed at 21 days Show forest plot

1

80

Risk Ratio (M‐H, Fixed, 95% CI)

1.0 [0.95, 1.05]

4 Wound healing: number of people healed at 12 days Show forest plot

1

80

Risk Ratio (M‐H, Fixed, 95% CI)

1.68 [1.17, 2.42]

5 Wound healing: number of people healed at 15 days Show forest plot

1

80

Risk Ratio (M‐H, Fixed, 95% CI)

1.16 [0.95, 1.41]

6 Wound healing: number of people healed at 18 days Show forest plot

1

80

Risk Ratio (M‐H, Fixed, 95% CI)

1.08 [0.97, 1.21]

7 Assessment of pain at baseline Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

8 Pain 30 minutes after treatment Show forest plot

1

118

Mean Difference (IV, Fixed, 95% CI)

‐0.79 [‐1.64, 0.06]

9 Overall assessment of pain at end of study Show forest plot

1

98

Mean Difference (IV, Fixed, 95% CI)

‐1.31 [‐2.37, ‐0.25]

10 Infection with Pseudomonas aeruginosa requiring antibiotic therapy Show forest plot

1

80

Risk Ratio (M‐H, Fixed, 95% CI)

0.33 [0.01, 7.95]

Figuras y tablas -
Comparison 5. Hydrogel dressing vs usual care
Comparison 6. Silicon nylon dressing vs silver sulphadiazine

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Number of dressing changes Show forest plot

1

66

Mean Difference (IV, Fixed, 95% CI)

‐1.49 [‐2.64, ‐0.34]

Figuras y tablas -
Comparison 6. Silicon nylon dressing vs silver sulphadiazine
Comparison 7. Biosynthetic skin substitute (Biobrane) vs silver sulphadiazine

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Pain Show forest plot

2

106

Mean Difference (IV, Random, 95% CI)

‐1.63 [‐2.20, ‐1.06]

2 Need for surgery Show forest plot

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

0.68 [0.21, 2.24]

Figuras y tablas -
Comparison 7. Biosynthetic skin substitute (Biobrane) vs silver sulphadiazine
Comparison 8. Antimicrobial‐releasing biosynthetic dressings vs silver sulphadiazine

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Wound infection Show forest plot

1

100

Risk Ratio (M‐H, Fixed, 95% CI)

1.88 [0.87, 4.02]

Figuras y tablas -
Comparison 8. Antimicrobial‐releasing biosynthetic dressings vs silver sulphadiazine
Comparison 9. Silver‐impregnated dressing vs silver sulphadiazine

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Wound healing time (days) Show forest plot

2

169

Mean Difference (IV, Fixed, 95% CI)

‐4.22 [‐5.92, ‐2.52]

2 Wound healing: number of people healed at 7 days Show forest plot

1

104

Risk Ratio (M‐H, Fixed, 95% CI)

1.5 [0.58, 3.91]

3 Wound healing: number of people healed at 10 days Show forest plot

1

104

Risk Ratio (M‐H, Fixed, 95% CI)

1.82 [0.97, 3.40]

4 Wound healing: number of people healed at 15 days Show forest plot

2

270

Risk Ratio (M‐H, Fixed, 95% CI)

1.17 [1.02, 1.35]

5 Wound healing: number of people healed at 17 days Show forest plot

1

104

Risk Ratio (M‐H, Fixed, 95% CI)

1.23 [0.98, 1.54]

6 Wound healing: number of people healed at 21 days Show forest plot

1

104

Risk Ratio (M‐H, Fixed, 95% CI)

1.21 [1.06, 1.37]

7 Healing rate (% wound area) Show forest plot

1

166

Mean Difference (IV, Fixed, 95% CI)

2.21 [‐2.37, 6.79]

8 Pain Show forest plot

3

135

Mean Difference (IV, Random, 95% CI)

‐2.84 [‐5.89, 0.21]

9 Need for surgery Show forest plot

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

0.67 [0.21, 2.08]

10 Number of infections Show forest plot

4

348

Risk Ratio (M‐H, Fixed, 95% CI)

1.04 [0.64, 1.67]

11 Number of wound dressings Show forest plot

1

65

Mean Difference (IV, Fixed, 95% CI)

‐11.07 [‐19.58, ‐2.56]

12 Nursing time (minutes) Show forest plot

1

65

Mean Difference (IV, Fixed, 95% CI)

‐4.82 [‐19.42, 9.78]

Figuras y tablas -
Comparison 9. Silver‐impregnated dressing vs silver sulphadiazine
Comparison 10. Fibre dressing vs silver sulphadiazine

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Wound healing time (days) Show forest plot

1

70

Mean Difference (IV, Fixed, 95% CI)

‐3.70 [‐5.44, ‐1.96]

2 Pain at day 1 Show forest plot

1

70

Mean Difference (IV, Fixed, 95% CI)

‐2.0 [‐3.03, ‐0.97]

3 Pain at day 3 Show forest plot

1

70

Mean Difference (IV, Fixed, 95% CI)

‐3.1 [‐4.02, ‐2.18]

4 Pain at day 7 Show forest plot

1

70

Mean Difference (IV, Fixed, 95% CI)

‐2.4 [‐3.18, ‐1.62]

5 Number of dressing changes Show forest plot

1

82

Mean Difference (IV, Fixed, 95% CI)

‐11.40 [‐15.66, ‐7.14]

6 Number of infections Show forest plot

1

82

Risk Ratio (M‐H, Fixed, 95% CI)

1.27 [0.48, 3.34]

7 Need for surgery Show forest plot

1

82

Risk Ratio (M‐H, Fixed, 95% CI)

0.68 [0.24, 1.97]

Figuras y tablas -
Comparison 10. Fibre dressing vs silver sulphadiazine