Dressings for superficial and partial thickness burns

Jason Wasiak; Heather Cleland; Fiona Campbell

doi:10.1002/14651858.CD002106.pub3

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Analysis 1.1

Comparison 1 Hydrocolloid dressing vs chlorhexidine impregnated gauze dressing, Outcome 1 Withdrawal due to wound infection.

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Analysis 2.1

Comparison 2 Hydrocolloid dressing vs silver sulphadiazine, Outcome 1 Number of dressing changes.

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Analysis 2.2

Comparison 2 Hydrocolloid dressing vs silver sulphadiazine, Outcome 2 Level of pain.

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Analysis 3.1

Comparison 3 Polyurethane film dressing vs paraffin gauze dressing, Outcome 1 Wound infection.

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Analysis 4.1

Comparison 4 Polyurethane film dressing vs chlorhexidine impregnated paraffin gauze dressing, Outcome 1 Wound infection.

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Analysis 5.1

Comparison 5 Hydrogel dressing vs usual care, Outcome 1 assessment of pain at baseline.

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Analysis 5.2

Comparison 5 Hydrogel dressing vs usual care, Outcome 2 pain 30 minutes after treatment.

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Analysis 5.3

Comparison 5 Hydrogel dressing vs usual care, Outcome 3 overall assessment of pain at end of study.

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Analysis 6.1

Comparison 6 Silicon nylon dressing vs silver sulphadiazine, Outcome 1 Number of dressing changes.

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Analysis 7.1

Comparison 7 Biosynthetic skin substitute (Biobrane) vs silver sulphadiazine, Outcome 1 Pain.

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Analysis 7.2

Comparison 7 Biosynthetic skin substitute (Biobrane) vs silver sulphadiazine, Outcome 2 Need for surgery.

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Analysis 8.1

Comparison 8 Antimicrobial releasing biosynthetic dressings vs silver sulphadiazine, Outcome 1 Wound infection.

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Analysis 9.1

Comparison 9 Silver impregnated dressing vs silver sulphadiazine, Outcome 1 Pain.

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Analysis 9.2

Comparison 9 Silver impregnated dressing vs silver sulphadiazine, Outcome 2 Need for surgery.

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Analysis 10.1

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 1 Number of dressing changes.

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Analysis 10.2

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 2 Number of infections.

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Analysis 10.3

Comparison 10 Fibre dressing vs silver sulphadiazine, Outcome 3 Need for surgery.

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Comparison 1. Hydrocolloid dressing vs chlorhexidine impregnated gauze dressing

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Withdrawal due to wound infection Show forest plot	1	68	Risk Ratio (M‐H, Fixed, 95% CI)	2.53 [0.11, 59.90]

Comparison 1. Hydrocolloid dressing vs chlorhexidine impregnated gauze dressing

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Comparison 2. Hydrocolloid dressing vs silver sulphadiazine

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Number of dressing changes Show forest plot	1	42	Mean Difference (IV, Fixed, 95% CI)	‐18.65 [‐19.48, ‐17.82]

2 Level of pain Show forest plot	1	42	Mean Difference (IV, Fixed, 95% CI)	‐1.19 [‐1.82, ‐0.56]

Comparison 2. Hydrocolloid dressing vs silver sulphadiazine

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Comparison 3. Polyurethane film dressing vs paraffin gauze dressing

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Wound infection Show forest plot	1	55	Risk Ratio (M‐H, Fixed, 95% CI)	1.25 [0.23, 6.90]

Comparison 3. Polyurethane film dressing vs paraffin gauze dressing

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Comparison 4. Polyurethane film dressing vs chlorhexidine impregnated paraffin gauze dressing

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Wound infection Show forest plot	1	51	Risk Ratio (M‐H, Fixed, 95% CI)	0.48 [0.05, 4.98]

Comparison 4. Polyurethane film dressing vs chlorhexidine impregnated paraffin gauze dressing

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Comparison 5. Hydrogel dressing vs usual care

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 assessment of pain at baseline Show forest plot	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected

2 pain 30 minutes after treatment Show forest plot	1	118	Mean Difference (IV, Fixed, 95% CI)	‐0.79 [‐1.64, 0.06]

3 overall assessment of pain at end of study Show forest plot	1	98	Mean Difference (IV, Fixed, 95% CI)	‐1.31 [‐2.37, ‐0.25]

Comparison 5. Hydrogel dressing vs usual care

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Comparison 6. Silicon nylon dressing vs silver sulphadiazine

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Number of dressing changes Show forest plot	1	66	Mean Difference (IV, Fixed, 95% CI)	‐1.49 [‐2.64, ‐0.34]

Comparison 6. Silicon nylon dressing vs silver sulphadiazine

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Comparison 7. Biosynthetic skin substitute (Biobrane) vs silver sulphadiazine

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Pain Show forest plot	2	106	Mean Difference (IV, Random, 95% CI)	‐1.63 [‐2.20, ‐1.06]

2 Need for surgery Show forest plot	1	50	Risk Ratio (M‐H, Fixed, 95% CI)	0.68 [0.21, 2.24]

Comparison 7. Biosynthetic skin substitute (Biobrane) vs silver sulphadiazine

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Comparison 8. Antimicrobial releasing biosynthetic dressings vs silver sulphadiazine

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Wound infection Show forest plot	1	100	Risk Ratio (M‐H, Fixed, 95% CI)	1.88 [0.87, 4.02]

Comparison 8. Antimicrobial releasing biosynthetic dressings vs silver sulphadiazine

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Comparison 9. Silver impregnated dressing vs silver sulphadiazine

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Pain Show forest plot	2	70	Mean Difference (IV, Random, 95% CI)	‐2.66 [‐6.27, 0.94]

2 Need for surgery Show forest plot	1	50	Risk Ratio (M‐H, Fixed, 95% CI)	0.67 [0.21, 2.08]

Comparison 9. Silver impregnated dressing vs silver sulphadiazine

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Comparison 10. Fibre dressing vs silver sulphadiazine

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Number of dressing changes Show forest plot	1	82	Mean Difference (IV, Fixed, 95% CI)	‐11.40 [‐15.66, ‐7.14]

2 Number of infections Show forest plot	1	82	Risk Ratio (M‐H, Fixed, 95% CI)	1.27 [0.48, 3.34]

3 Need for surgery Show forest plot	1	82	Risk Ratio (M‐H, Fixed, 95% CI)	0.68 [0.24, 1.97]

Comparison 10. Fibre dressing vs silver sulphadiazine

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