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Cochrane Database of Systematic Reviews

Interferón para la esclerosis múltiple recurrente‐remitente

Información

DOI:
https://doi.org/10.1002/14651858.CD002002Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 23 octubre 2001see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Esclerosis múltiple y enfermedades raras del sistema nervioso central

Copyright:
  1. Copyright © 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Autores

  • George PA Rice

    Clinical Neurological Sciences, University of Western Ontario, London, Canada

  • Barbara Incorvaia

    Cochrane Neurological Network, Osservatorio Epidemiologico ‐ Regione Umbria, Perugia, Italy

  • Luca M. Munari

    Azienda Ospedaliera Ospedale Niguarda Ca' Granda, Milan, Italy

  • George Ebers

    Clinical Neurology, University of Oxford, Oxford, UK

  • Chris Polman

    Neurology, VU Medical Centre, Amsterdam, Netherlands

  • Roberto D'Amico

    Department of Oncology and Hematology, University of Modena and Reggio Emilia, Modena, Italy

  • Elena Parmelli

    Department of Oncology and Hematology, University of Modena and Reggio Emilia, Modena, Italy

  • Graziella Filippini

    Correspondencia a: Neuroepidemiology Unit, Fondazione I.R.C.C.S. ‐ Istituto Neurologico C.Besta, Milano, Italy

    [email protected]

Contributions of authors

Prof G PA Rice and Dr G Filippini conceived the idea and development of the project, posed the questions of the research project, designed the protocol, appraised the relevance and the validity of the papers and co‐ordinated the review. G Rice abstracted data and wrote to sponsors of trials for additional information. They both analyzed the results and wrote the text of the review.
Dr B Incorvaia and Dr L Munari: They both were involved in the search strategy, abstracted data and helped in the analysis of the results and writing of the test of the review. Dr B Incorvaia organized retrieval of papers.
Prof Chris Polman: Assisted in the design of the protocol, abstracted data, assisted in data interpretation and reviewed the manuscript drafts.
Dr R D'Amico assisted in statistical analysis and writing of the test of the review.
Prof George Ebers: Assisted in the design of the protocol, data interpretation and reviewed the manuscript drafts.
Dr E Parmelli collaborated to the update of the review.

Sources of support

Internal sources

  • Department of Clinical Neurological Sciences, University of Western Ontario, Canada.

  • National Neurological Institute C. Besta, Milan, Italy.

External sources

  • Multiple Sclerosis Society of Canada (applied), Canada.

  • Fondazione Italiana Sclerosi Multipla, Italy.

Declarations of interest

The review was assembled, analysed and reported independent from any pharmaceutical company input.
Prof Rice has participated in clinical trials sponsored by SCHERING, SERONO, BERLEX, BIOGEN, and TEVA. He has received honoraria from these companies.
Prof Ebers has received honoraria for lectures found to be sponsored by relevant companies and has been an investigator for several clinical trials in multiple sclerosis including three interferon studies involving SCHERING, SERONO funding. He does not feel his opinions (which are largely critical of the efficacy of interferons) are influenced by these associations.
Prof Polman has received honoraria for lecturing, consultancy from companies producing interferon beta.
Dr Filippini has received travel expenses from Farmades pharmaceutical company for participating at neurological conferences.
Drs Munari, D'Amico, Incorvaia and Parmelli have no conflict of interest.

Acknowledgements

Authors wish to thank Prof Jon Deeks (Centre for Statistics in Medicine, Institute of Health Sciences, Oxford UK ), Prof Alessandro Liberati and Ms Elena Telaro (Italian Cochrane Centre), Dr Bernard MJ Uitdehaag (VU Medical Centre, Amsterdam, The Netherlands), Prof Silvio Garattini and Dr Walter Torri (Istituto di Ricerche "Mario Negri", Milan Italy), Prof Alan Thompson (Department of Clinical Neurology, National Hospital for Neurology and Neurosurgery, London, UK), Prof Silvana Simi, Prof Daniela Lupo and Mr Lorenzo Brait (participant consumers of the Cochrane MS Group) for useful comments during the preparation of the manuscript.

Version history

Published

Title

Stage

Authors

Version

2001 Oct 23

Interferon in relapsing‐remitting multiple sclerosis

Review

George PA Rice, Barbara Incorvaia, Luca M. Munari, George Ebers, Chris Polman, Roberto D'Amico, Elena Parmelli, Graziella Filippini

https://doi.org/10.1002/14651858.CD002002