Antibiotici za nepotpuni pobačaj
Abstract
Background
Unsafe abortions result not only in costs for acute care but may also be responsible for longer‐term complications such as pelvic inflammatory disease, damage to reproductive organs, and secondary infertility. If effective, antibiotic prophylaxis at the time of the procedure can potentially prevent these adverse consequences.
Objectives
The value of routine antibiotics before surgical evacuation of the uterus in women with incomplete abortion is controversial. In some health centres antibiotic prophylaxis is advised; in others antibiotics are only prescribed when there are signs of infection. The objective of this review is to evaluate the effectiveness of routine antibiotic prophylaxis to women with incomplete abortion.
Search methods
We searched the Cochrane Controlled Trials Register, Pubmed/MEDLINE, EMBASE and Popline. Date of last search: January 2007.
Selection criteria
Randomised trials comparing a policy of routine antibiotic prophylaxis with no routine prophylaxis were eligible for inclusion.
Data collection and analysis
Data extraction was conducted by two reviewers independently. Trial quality was assessed.
Main results
One study involving 140 women was included. A second well‐conducted trial was excluded because of high losses to follow‐up. No differences were detected in postabortal infection rates with routine prophylaxis or control. However, compliance with antibiotic treatment was also low.
Authors' conclusions
There is not enough evidence to evaluate a policy of routine antibiotic prophylaxis to women with incomplete abortion.
PICO
Plain language summary
Nema dovoljno dokaza o rutinskoj primjeni antibiotika kako bi se spriječila infekcija kod žena nakon nepotpunog pobačaja, ali jedna doza bi mogla biti prikladnija
Nepotpuni pobačaj uzrokuje mnoge komplikacije i smrt desetaka tisuća žena svake godine. Žene koje traže zdravstvenu skrb nakon nepotpunog pobačaja obično dolaze zbog problema vezanih za intenzivno krvarenje ili infekciju. Antibiotici se obično primjenjuju kada postoje znakovi infekcije. Ovaj sustavni pregled je pokazao poteškoće kad je riječ o nastavku uzimanja antibiotika i povratka žena za nastavak zdravstvene skrbi, pa bi jednokratne doze antibiotika mogle biti prikladnije u takvim okolnostima. Ispitivanja nisu dala dovoljno dokaza koji bi pokazali učinke rutinske primjene antibiotika za žene nakon nepotpunog pobačaja.
