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Comparison 1 Ribavirin versus Placebo, Outcome 1 Mortality.
Figuras y tablas -
Analysis 1.1

Comparison 1 Ribavirin versus Placebo, Outcome 1 Mortality.

Comparison 1 Ribavirin versus Placebo, Outcome 2 Respiratory deterioration.
Figuras y tablas -
Analysis 1.2

Comparison 1 Ribavirin versus Placebo, Outcome 2 Respiratory deterioration.

Comparison 1 Ribavirin versus Placebo, Outcome 3 Length of hospitalization in days with saline placebo.
Figuras y tablas -
Analysis 1.3

Comparison 1 Ribavirin versus Placebo, Outcome 3 Length of hospitalization in days with saline placebo.

Comparison 1 Ribavirin versus Placebo, Outcome 4 Length of hospitalization in days all studies.
Figuras y tablas -
Analysis 1.4

Comparison 1 Ribavirin versus Placebo, Outcome 4 Length of hospitalization in days all studies.

Comparison 1 Ribavirin versus Placebo, Outcome 5 Length of ventilation in days with saline placebo.
Figuras y tablas -
Analysis 1.5

Comparison 1 Ribavirin versus Placebo, Outcome 5 Length of ventilation in days with saline placebo.

Comparison 1 Ribavirin versus Placebo, Outcome 6 Length of ventilation in days all studies.
Figuras y tablas -
Analysis 1.6

Comparison 1 Ribavirin versus Placebo, Outcome 6 Length of ventilation in days all studies.

Comparison 1 Ribavirin versus Placebo, Outcome 8 Oxygen dependence in days.
Figuras y tablas -
Analysis 1.8

Comparison 1 Ribavirin versus Placebo, Outcome 8 Oxygen dependence in days.

Comparison 1 Ribavirin versus Placebo, Outcome 13 Post‐viral reactive airways disease.
Figuras y tablas -
Analysis 1.13

Comparison 1 Ribavirin versus Placebo, Outcome 13 Post‐viral reactive airways disease.

Comparison 1. Ribavirin versus Placebo

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mortality Show forest plot

4

158

Peto Odds Ratio (Peto, Fixed, 95% CI)

0.56 [0.17, 1.84]

2 Respiratory deterioration Show forest plot

3

116

Peto Odds Ratio (Peto, Fixed, 95% CI)

0.38 [0.13, 1.11]

3 Length of hospitalization in days with saline placebo Show forest plot

2

78

Mean Difference (IV, Fixed, 95% CI)

‐1.87 [‐4.81, 1.08]

4 Length of hospitalization in days all studies Show forest plot

3

104

Mean Difference (IV, Fixed, 95% CI)

‐1.85 [‐4.59, 0.90]

5 Length of ventilation in days with saline placebo Show forest plot

2

78

Mean Difference (IV, Fixed, 95% CI)

‐1.08 [‐2.83, 0.67]

6 Length of ventilation in days all studies Show forest plot

3

104

Mean Difference (IV, Fixed, 95% CI)

‐1.79 [‐3.37, ‐0.21]

7 Long‐term pulmonary function

0

0

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

8 Oxygen dependence in days Show forest plot

3

104

Mean Difference (IV, Fixed, 95% CI)

‐1.87 [‐3.88, 0.14]

9 Change in severity of illness

Other data

No numeric data

10 Improvement in oxygenation

0

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

11 Pulmonary function

0

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

12 Toxic or side effects

Other data

No numeric data

13 Post‐viral reactive airways disease Show forest plot

1

35

Odds Ratio (M‐H, Fixed, 95% CI)

0.17 [0.03, 0.83]

Figuras y tablas -
Comparison 1. Ribavirin versus Placebo