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Cochrane Database of Systematic Reviews

Sedation for moderate‐to‐severe traumatic brain injury in adults: a network meta‐analysis

Information

DOI:
https://doi.org/10.1002/14651858.CD012639Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 21 April 2017see what's new
Type:
  1. Intervention
Stage:
  1. Protocol
Cochrane Editorial Group:

  1. Cochrane Injuries Group

Copyright:
  1. Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Lisa Burry

    Correspondence to: Department of Pharmacy, Mount Sinai Hospital, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada

    [email protected]

  • Lindsay Dryden

    Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada

  • Louise Rose

    Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Canada

  • David R Williamson

    Faculty of Pharmacy / Department of Pharmacy, Université de Montréal / Höpital du Sacré‐Coeur de Montréal, Montreal, Canada

  • Neill KJ Adhikari

    Interdepartmental Division of Critical Care, University of Toronto, Toronto, Canada

  • Alexis F Turgeon

    Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, and Population Health and Optimal Health Practices Research Unit (Trauma ‐ Emergency ‐ Critical Care Medicine), CHU de Québec ‐ Université Laval Research Center, CHU de Québec ‐ Université Laval, Université Laval, Quebec City, Canada

  • Eyal Golan

    Department of Medicine, University Health Network, Toronto, Canada

  • Norman Dewhurst

    Department of Pharmacy, St. Michael’s Hospital, Toronto, Canada

  • Dean A Fergusson

    Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada

  • Brian Hutton

    Knowledge Synthesis Group, Ottawa Hospital Research Institute, Ottawa, Canada

  • Sangeeta Mehta

    Interdepartmental Division of Critical Care Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Canada

Contributions of authors

Drafting of protocol: LB; LD; LR; DW; NA; AT; EG; ND; DF; BH; and SM.

Sources of support

Internal sources

  • None, Other.

External sources

  • No sources of support supplied

Declarations of interest

LB: none known.

LD: none known.

LR: none known.

DW: has received an educational research grant from Hospira (now Pfizer), the company that makes Precedex (dexmedetomidine).

NA: none known.

AT: none known.

EG: none known.

ND: none known.

DF: none known.

BH: none known.

SM: none known.

Acknowledgements

We would like to acknowledge Deirdre Beecher and Sarah Dawson, Information Specialists with the Cochrane Injuries Group, for their assistance with the development of the search strategy for this review. We would also like to thank Dr Victoria McCredie, Intensivist at Toronto Western Hospital for input on the development of the methodology for this review. Lastly, we would like to thank Melanie Guenette, Research Co‐ordinator, Department of Pharmacy, Mount Sinai Hospital, for her editorial assistance in the publication of this protocol.

This project was supported by the UK National Institute for Health Research, through Cochrane Infrastructure funding to the Cochrane Injuries Group. The views and opinions expressed are those of the authors and do not necessarily reflect those of the Systematic Reviews Programme, NIHR, NHS or the Department of Health.

Version history

Published

Title

Stage

Authors

Version

2017 Apr 21

Sedation for moderate‐to‐severe traumatic brain injury in adults: a network meta‐analysis

Protocol

Lisa Burry, Lindsay Dryden, Louise Rose, David R Williamson, Neill KJ Adhikari, Alexis F Turgeon, Eyal Golan, Norman Dewhurst, Dean A Fergusson, Brian Hutton, Sangeeta Mehta

https://doi.org/10.1002/14651858.CD012639

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.