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Cochrane Database of Systematic Reviews

N‐acetylcarnosine (NAC) drops for age‐related cataract

Information

DOI:
https://doi.org/10.1002/14651858.CD009493.pub2Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 28 February 2017see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:
  1. Cochrane Eyes and Vision Group

Copyright:
  1. Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Vincent DJ‐P Dubois

    Correspondence to: Elective Care Centre, Aintree University Hospital NHS Foundation Trust, Liverpool, UK

    [email protected]

  • Andrew Bastawrous

    Mersey Deanery, Liverpool, UK

    International Centre for Eye Health, London School of Hygiene & Tropical Medicine, London, UK

Contributions of authors

  • Conceiving the review: Cochrane Eyes and Vision

  • Designing the review: VD

  • Co‐ordinating the review: VD

  • Data collection for the review

    • designing electronic search strategies: Cochrane Eyes and Vision editorial team

    • undertaking manual searches: VD

    • screening search results: VD, AB

    • organising retrieval of papers: Cochrane Eyes and Vision Group editorial team

    • screening retrieved papers against inclusion criteria: VD, AB

    • appraising quality of papers: VD, AB

    • extracting data from papers: VD, AB

    • writing to authors of papers for additional information: VD

    • providing additional data about papers: VD

    • obtaining and screening data on unpublished studies: VD

  • Data management for the review

    • entering data into RevMan: VD

    • checking data entered into RevMan: AB

  • Analysis of data: VD

  • Interpretation of data: VD

  • Providing a methodological perspective: VD

  • Providing a clinical perspective: VD

  • Writing the review: VD

  • Providing general advice on the review: Richard Wormald

Sources of support

Internal sources

  • No sources of support supplied

External sources

  • National Institute for Health Research (NIHR), UK.

    • Richard Wormald, Co‐ordinating Editor for Cochrane Eyes and Vision (CEV) acknowledges financial support for his CEV research sessions from the Department of Health through the award made by the NIHR to Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology for a Specialist Biomedical Research Centre for Ophthalmology.

    • The NIHR also funds the CEV Editorial Base in London.

    The views expressed in this publication are those of the authors and not necessarily those of the NIHR, NHS, or the Department of Health.

Declarations of interest

VD: None known
AB: None known

Acknowledgements

Cochane Eyes and Vision created and executed the electronic search strategies. We thank

  • Catey Bunce and Miriam Minihan for their comments on this protocol.

  • Sonal Singh and Michael Hennessy for their comments on the review.

  • Jennifer Evans and Anupa Shah for their advice and assistance throughout the development of the protocol/review.

Version history

Published

Title

Stage

Authors

Version

2017 Feb 28

N‐acetylcarnosine (NAC) drops for age‐related cataract

Review

Vincent DJ‐P Dubois, Andrew Bastawrous

https://doi.org/10.1002/14651858.CD009493.pub2

2011 Dec 07

N‐acetylcarnosine (NAC) drops for age‐related cataract

Protocol

Vincent DJ‐P Dubois, Andrew Bastawrous

https://doi.org/10.1002/14651858.CD009493

Differences between protocol and review

Adverse effects were omitted from the protocol but have been included in the review. Using the GRADE approach was not included in the protocol but was adapted for the review.

Keywords

MeSH

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.

Study flow diagram.
Figures and Tables -
Figure 1

Study flow diagram.