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Cochrane Database of Systematic Reviews

Droperidol for treatment of nausea and vomiting in palliative care patients

Information

DOI:
https://doi.org/10.1002/14651858.CD006938.pub3Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 27 November 2014see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:
  1. Cochrane Pain, Palliative and Supportive Care Group

Copyright:
  1. Copyright © 2014 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Jemma Storrar

    Wessex Higher Training Programme Palliative Medicine, Wessex, UK

  • Morwenna Hitchens

    Wessex Higher Training Programme Palliative Medicine, Wessex, UK

  • Tracey Platt

    Wessex Higher Training Programme Palliative Medicine, Wessex, UK

  • Saskie Dorman

    Correspondence to: Palliative Medicine, Poole Hospital NHS Foundation Trust, Poole, UK

    [email protected]

    [email protected]

Contributions of authors

SD and Paul Perkins designed the original systematic review. SD and Sylvia Bickley developed the search strategy with comments from PP. SD and PP independently reviewed all titles and abstracts yielded by the search strategy (2010) and discussed any discrepancies to achieve a consensus. JS, MH and TP independently reviewed all abstracts yielded by the updated searches (2013); full papers were reviewed independently by JS, MH, TP and SD. JS, MH and TP updated the text of the review which SD wrote in 2010 with input from PP. SD is the corresponding author and contact for future updates.

Sources of support

Internal sources

  • Poole Hospital NHS Foundation Trust, UK

    Library services

  • Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust, UK

    Library Services

  • Southampton University Hospital Trust, UK

    Library Services

External sources

  • The Cochrane Collaboration, UK

    Searches and editorial review

Declarations of interest

JS: None known.

MH: None known.

TP: None known.

SD: None known.

Acknowledgements

For the 2010 review we would like to thank the staff of the Cochrane Pain, Palliative & Supportive Care Review Group, including Jessica Thomas, Yvonne Roy, Anna Hobson, Sylvia Bickley for help with refining the search strategy, Caroline Struthers for updating the search, Mari Imamura for translation of two Japanese papers, and our peer referees, Giovambattista Zeppetella and Janet Wale, who commented on the draft of the protocol for this systematic review, and Karl Gallegos, Gerhild Becker and Andrew Moore who commented on the review. Thanks also to Linda Porter and Lyn Jackson (pharmacists) and Susan Merner (librarian) at Poole Hospital NHS Foundation Trust.

For the updated 2013 review we would like to thank Jo Abbott (Trials Search Co‐ordinator), Jane Hayes, Yvonne Roy, Mike Bennett and Phil Wiffen at The Cochrane Collaboration. We would also like to thank the librarians at the Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust, University Hospital Southampton NHS Foundation Trust and Barbara Peirce at Poole Hospital NHS Foundation Trust.

Cochrane Review Group funding acknowledgement: The National Institute for Health Research (NIHR) is the largest single funder of the Cochrane PaPaS Group. Disclaimer: The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the NIHR, National Health Service (NHS) or the Department of Health.

Version history

Published

Title

Stage

Authors

Version

2014 Nov 27

Droperidol for treatment of nausea and vomiting in palliative care patients

Review

Jemma Storrar, Morwenna Hitchens, Tracey Platt, Saskie Dorman

https://doi.org/10.1002/14651858.CD006938.pub3

2010 Oct 06

Droperidol for treatment of nausea and vomiting in palliative care patients

Review

Saskie Dorman, Paul Perkins

https://doi.org/10.1002/14651858.CD006938.pub2

2008 Jan 23

Droperidol for treatment of nausea and vomiting in palliative care patients

Protocol

Saskie Dorman, Paul Perkins

https://doi.org/10.1002/14651858.CD006938

Differences between protocol and review

We excluded studies of antiemetics used for the prophylaxis of nausea or vomiting associated with chemotherapy.

Notes

In May 2020, we performed a restricted updated search on MEDLINE, and also searched trial registries for relevant ongoing studies. We did not identify any potentially relevant studies for inclusion. The authors acknowledge that the number of publications on this topic has been steadily decreasing since 2002, and that most new publications relate to a postoperative setting rather than palliative care. Therefore, this review has now been stabilised following discussion between the authors and editors. If appropriate, we will update the review if new evidence likely to change the conclusions is published, or if standards change substantially which necessitate major revisions.

Keywords

MeSH

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.

Study flow diagram.

Figures and Tables -
Figure 1

Study flow diagram.