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Cochrane Database of Systematic Reviews

Antidepressants for neuropathic pain

Information

DOI:
https://doi.org/10.1002/14651858.CD005454.pub2Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 17 October 2007see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:

  1. Cochrane Pain, Palliative and Supportive Care Group

Copyright:
  1. Copyright © 2014 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Tiina Saarto

    Correspondence to: Cancer Center, Helsinki University Central Hospital, Helsinki, Finland

    [email protected]

  • Philip J Wiffen

    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK

Contributions of authors

TS identified the studies, extracted information and data, undertook the analysis, and wrote the first draft.
PW checked and updated searches, wrote the second draft and undertook some new data calculations
Both review authors agreed the final draft.
For this update the authors independently extracted data, met to agree data to be included and both wrote and agreed the final version.

Sources of support

Internal sources

  • UK Cochrane Centre, UK.

  • NHS Research and Development, UK.

External sources

  • Finnish Association of Pain Research, Finland.

Declarations of interest

None known

Acknowledgements

Frances Fairman devised the original data extraction form, was involved in study selection for the first publication, helped with the search strategy, obtained papers, and contributed to final drafts. She was not involved in this update. Anne Eisinga at the UK Cochrane Centre helped with data extraction of an Italian language paper.

Version history

Published

Title

Stage

Authors

Version

2007 Oct 17

Antidepressants for neuropathic pain

Review

Tiina Saarto, Philip J Wiffen

https://doi.org/10.1002/14651858.CD005454.pub2

2005 Jul 20

Antidepressants for neuropathic pain

Review

Tiina Saarto, Philip J Wiffen

https://doi.org/10.1002/14651858.CD005454

Notes

September 2009: This review is being updated by being split into smaller components. The first will be a review of the effectiveness of amitriptyline which is widely used to treat neuropathic pain.

January 2014: The following reviews and protocols have been published, or are in development:

Amitriptyline for neuropathic pain and fibromyalgia in adults

Milnacipran for neuropathic pain and fibromyalgia in adults

Venlafaxine for neuropathic pain

Imipramine for neuropathic pain in adults

Desipramine for neuropathic pain in adults

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.