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Cochrane Database of Systematic Reviews

Drugs for treating uncomplicated malaria in pregnant women

Information

DOI:
https://doi.org/10.1002/14651858.CD004912.pub3Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 08 October 2008see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:

  1. Cochrane Infectious Diseases Group

Classified:
  1. No update planned

    Other

    Not a current question. The issue with ACTs in pregnancy is safety, and there is a comprehensive systematic review on this topic published by Dellicour 2017 https://doi.org/10.1371/journal.pmed.1002290 in PLoS Medicine

    Assessed: 23 April 2019

Copyright:
  1. Copyright © 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Lois C Orton

    Correspondence to: School of Nursing, Midwifery and Social Work, University of Manchester, Manchester, UK

    [email protected]

  • Aika AA Omari

    Alder Hey Children's Hospital, Liverpool, UK

Contributions of authors

Lois Orton assessed eligibility, extracted data, and wrote the review. For the review update, Aika Omari assessed eligibility, extracted data, and helped write the review.

Sources of support

Internal sources

  • No sources of support supplied

External sources

  • Department for International Development, UK.

Declarations of interest

None known.

Acknowledgements

We thank Bernard Brabin and Francine Verhoeff for their comments during the development of the protocol for this review. We thank Paul Garner for his contributions as an author to the original version of the review (Orton 2005). The Liverpool School of Tropical Medicine provided support to Paul Garner.

The editorial base for the Cochrane Infectious Diseases Group is funded by the UK Department for International Development (DFID) for the benefit of developing countries.

Version history

Published

Title

Stage

Authors

Version

2008 Oct 08

Drugs for treating uncomplicated malaria in pregnant women

Review

Lois C Orton, Aika AA Omari

https://doi.org/10.1002/14651858.CD004912.pub3

2005 Jul 20

Drugs for treating uncomplicated malaria in pregnant women

Review

Lois C Orton, Paul Garner

https://doi.org/10.1002/14651858.CD004912.pub2

2004 Jul 19

Drugs for treating uncomplicated malaria in pregnant women

Protocol

Lois C Orton, Paul Garner

https://doi.org/10.1002/14651858.CD004912

Differences between protocol and review

When we prepared the first version of the review (Orton 2005), we made some changes to the protocol. We specified the inclusion of quasi‐randomized controlled trials, split the outcome measures into "maternal treatment response", "maternal adverse events", and "fetal outcomes" for added clarity, and excluded placental infection as an outcome measure because it is not a measure of treatment response. We also updated the methods for assessing blinding, changed the phrase "loss to follow up" to "inclusion of all randomized participants in the analysis" to reflect changes within the Cochrane Infectious Diseases Group, and decided to use only the chi‐squared test for heterogeneity (and not the I2).