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Cochrane Database of Systematic Reviews

Methotrexate for induction of remission in refractory Crohn's disease

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view the current version 06 August 2014

Information

DOI:
https://doi.org/10.1002/14651858.CD003459.pub3Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 12 December 2012see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:

  1. Cochrane Gut Group

Copyright:
  1. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • John WD McDonald

    Correspondence to: Robarts Clinical Trials, Robarts Research Institute, London, Canada

    [email protected]

  • David J Tsoulis

    Robarts Clinical Trials, Robarts Research Institute, London, Canada

  • John K MacDonald

    Robarts Clinical Trials, Robarts Research Institute, London, Canada

  • Brian G Feagan

    Robarts Clinical Trials, Robarts Research Institute, London, Canada

Declarations of interest

Brian Feagan and John McDonald are authors of a manuscript that was included in this review. Brian Feagan has received lecture fee(s) from: GlaxoSmithKline, Procter & Gamble Pharmaceuticals, Salix Pharmaceuticals Inc, Shire Pharmaceuticals Inc, Tillotts Pharma AG and Merck. John MacDonald has served as a consultant for Tillotts Pharma AG. All of these financial activities are outside the submitted work. The other authors have no known declarations of interest.

Acknowledgements

Funding for the IBD/FBD Review Group (September 1, 2010 ‐ August 31, 2015) has been provided by the Canadian Institutes of Health Research (CIHR) Knowledge Translation Branch (CON ‐ 105145) and the CIHR Institutes of Nutrition, Metabolism and Diabetes (INMD); and Infection and Immunity (III) and the Ontario Ministry of Health and Long Term Care (HLTC3968FL‐2010‐2235).

Miss Ila Stewart has provided support for the IBD/FBD Review Group through the Olive Stewart Fund.

Version history

Published

Title

Stage

Authors

Version

2014 Aug 06

Methotrexate for induction of remission in refractory Crohn's disease

Review

John WD McDonald, Yongjun Wang, David J Tsoulis, John K MacDonald, Brian G Feagan

https://doi.org/10.1002/14651858.CD003459.pub4

2012 Dec 12

Methotrexate for induction of remission in refractory Crohn's disease

Review

John WD McDonald, David J Tsoulis, John K MacDonald, Brian G Feagan

https://doi.org/10.1002/14651858.CD003459.pub3

2004 Oct 18

Methotrexate for induction of remission in refractory Crohn's disease

Review

Ahmad AF Alfadhli, John WD McDonald, Brian G Feagan

https://doi.org/10.1002/14651858.CD003459.pub2

2002 Oct 21

Methotrexate for induction of remission in Crohn's disease

Protocol

A AF Alfadhli, John W McDonald, B G Feagan

https://doi.org/10.1002/14651858.CD003459

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.