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Cochrane Database of Systematic Reviews

Antiplatelet therapy for preventing stroke in patients with non‐valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks

Information

DOI:
https://doi.org/10.1002/14651858.CD001925.pub2Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 19 October 2005see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:

  1. Cochrane Stroke Group

Copyright:
  1. Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Maria I Aguilar

    Department of Neurology, Mayo Clinic Arizona, Phoenix, USA

  • Robert Hart

    Correspondence to: Division of Neurology, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, USA

    [email protected]

Contributions of authors

Drs Aguilar and Hart updated the systematic review, screened and appraised the quality of published papers, abstracted data from included studies, communicated with investigators regarding unpublished data, interpreted the analyses, and wrote the review.

Declarations of interest

Dr Hart was a leader of the SPAF I trial that was included in this review.

Acknowledgements

The AFASAK I and SPAF I investigators allowed access to their data in the Atrial Fibrillation Investigators database to assess unpublished outcomes. The LASAF investigators provided unpublished data about specific outcomes.

We acknowledge with gratitude the valuable contributions of Oscar Benavente (San Antonio, USA), Peter J Koudstaal (Rotterdam, The Netherlands), Andreas Laupacis (Toronto, Canada), and Ruth McBride (Seattle, USA) to the design and previous version of this review published in 2000.

Thanks to Hazel Fraser, the Review Group Co‐ordinator of the Cochrane Stroke Group for searching the Cochrane Stroke Group's Trials Register.

Version history

Published

Title

Stage

Authors

Version

2005 Oct 19

Antiplatelet therapy for preventing stroke in patients with non‐valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks

Review

Maria I Aguilar, Robert Hart

https://doi.org/10.1002/14651858.CD001925.pub2

1999 Oct 25

Antiplatelet therapy for preventing stroke in patients with non‐valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks

Review

Oscar Benavente, Robert Hart, Peter J Koudstaal, Andreas Laupacis, Ruth McBride

https://doi.org/10.1002/14651858.CD001925

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.