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Cochrane Database of Systematic Reviews

Single dose oral ibuprofen for acute postoperative pain in adults

Information

DOI:
https://doi.org/10.1002/14651858.CD001548.pub2Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 08 July 2009see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:
  1. Cochrane Pain, Palliative and Supportive Care Group

Copyright:
  1. Copyright © 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Christopher J Derry

    Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics), University of Oxford, Oxford, UK

  • Sheena Derry

    Correspondence to: Oxford, UK

    [email protected]

  • R Andrew Moore

    Plymouth, UK

  • Henry J McQuay

    Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics), University of Oxford, Oxford, UK

Contributions of authors

CD and SD carried out searches, identified studies for inclusion, and carried out data extraction and analysis. SD entered the data into RevMan. RAM was involved with analysis and writing. HJM acted as arbitrator and was involved with writing. SD will be responsible for conducting the next update of this review.

Sources of support

Internal sources

  • Oxford Pain Research funds, UK.

External sources

  • NHS Cochrane Collaboration Programme Grant Scheme, UK.

  • NIHR Biomedical Research Centre Programme, UK.

Declarations of interest

RAM and HJM have consulted for various pharmaceutical companies. RAM and HJM have received lecture fees from pharmaceutical companies related to analgesics and other healthcare interventions. RAM, HJM and SD have received research support from charities, government and industry sources at various times. Support for this review came from Oxford Pain Research, the NHS Cochrane Collaboration Programme Grant Scheme, and NIHR Biomedical Research Centre Programme.

Acknowledgements

Sally Collins, Phil Wiffen and Jayne Rees (Edwards) were authors on the earlier review. For the earlier review Clare Abbott at the Cairns Library, Churchill Hospital, and Catherine Strong (Novartis medical information services) and Darren Bloore (Knoll library) helped with obtaining papers. Laska provided additional information on his study.

Version history

Published

Title

Stage

Authors

Version

2009 Jul 08

Single dose oral ibuprofen for acute postoperative pain in adults

Review

Christopher J Derry, Sheena Derry, R Andrew Moore, Henry J McQuay

https://doi.org/10.1002/14651858.CD001548.pub2

1999 Jan 25

Single dose oral ibuprofen for acute postoperative pain in adults

Review

Sally Collins, R Andrew Moore, Henry J McQuay, Philip J Wiffen, Jayne Rees, Sheena Derry

https://doi.org/10.1002/14651858.CD001548

Differences between protocol and review

There are no major differences between the protocol and review.

Notes

We performed a restricted search in June 2017. We are aware of some additional relevant studies, but given the existing wealth of information, the large numbers of studies and participants, the stability of the efficacy estimate over time, and the fact that due attention has been given to issues over formulation, it is unlikely that any update will change the conclusions. Therefore, this review has now been stabilised following discussion with the authors and editors. If appropriate, we will update the review if new evidence likely to change the conclusions is published, or if standards change substantially which necessitate major revisions.

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.