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Cochrane Database of Systematic Reviews

Bronchodilators for bronchiolitis

This is not the most recent version

Information

DOI:
https://doi.org/10.1002/14651858.CD001266.pub3Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 08 December 2010see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:
  1. Cochrane Acute Respiratory Infections Group

Copyright:
  1. Copyright © 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Anne M Gadomski

    Correspondence to: Research Institute, Bassett Medical Center, Cooperstown, USA

    [email protected]

  • Melissa Brower

    Computing Center, Bassett Medical Center, Cooperstown, USA

Contributions of authors

For the 2006 update, Anne Gadomski (AG) reviewed all the searches, selected studies and contacted authors to request unpublished data. AG identified outcomes of trials relevant for inclusion, reviewed the results and wrote the discussion and conclusions. Alice Bhasale (AB) assisted with some of the searches and selection of studies, data entry and analyses.

For the 2010 update, AG and Melissa Brower (MB) reviewed all the searches, selected studies, reviewed the included studies for risk of bias as well as outcomes, and reviewed meta‐analysis results. MB performed the meta‐analysis and sensitivity analysis. AG contacted authors to request unpublished data and updated the text of the review.

Sources of support

Internal sources

  • National Prescribing Service Pty Ltd, Australia.

External sources

  • No sources of support supplied

Declarations of interest

AM Gadomski is a trialist in included studies.

Acknowledgements

We wish to thank Drs A Alario, T Klassen, L Landau, D Lines, S Schuh and P Schweich for providing unpublished data from their studies. We are also grateful to Mr Derek Stephens and Ms Terri Myhr, of Toronto for their assistance with the statistical analyses performed for the original review. The original review was presented in part at the annual meeting of the Ambulatory Pediatric Association: May 1994, Seattle, Washington.

We would like to acknowledge the contributions of three of the original co‐authors, JD Kellner, A Ohlsson and EEL Wang in conducting the original work for this review on which this update is based (Kellner 1998). Drs F Gurkan, B Karadag and H Patel generously provided unpublished data from their studies for the 2006 update. Drs. Tinsa and S Ralston graciously provided unpublished data from their studies for the 2010 update. The assistance of Sarah Thorning in conducting the searches for the update is also appreciated.

Taixiang Wu provided invaluable assistance in assessing eligibility of trials published in the Chinese language. The support of the National Prescribing Service (NPS), Australia allowed A Bhasale to contribute to this update and is appreciated. Reviews were received with thanks from the following peer referees: Alison Thomas, Craig Mellis, Rob Ware, Juan Lozano, Amanda Young, David Isaacs, Nelcy Rodriguez‐Malagon, and Inge Axelsson. Finally we would like to acknowledge with thanks the support and guidance of Liz Dooley, Managing Editor for the Cochrane ARI Group, throughout the 2006 and 2010 updates.

Version history

Published

Title

Stage

Authors

Version

2014 Jun 17

Bronchodilators for bronchiolitis

Review

Anne M Gadomski, Melissa B Scribani

https://doi.org/10.1002/14651858.CD001266.pub4

2010 Dec 08

Bronchodilators for bronchiolitis

Review

Anne M Gadomski, Melissa Brower

https://doi.org/10.1002/14651858.CD001266.pub3

2006 Jul 19

Bronchodilators for bronchiolitis

Review

Anne M Gadomski, Alice L Bhasale

https://doi.org/10.1002/14651858.CD001266.pub2

1999 Jan 25

Bronchodilators for bronchiolitis

Review

James Kellner, Arne Ohlsson, Anne Gadomski, Elaine EL Wang

https://doi.org/10.1002/14651858.CD001266

Differences between protocol and review

Oxygen saturation was designated as the primary outcome in the 2010 update. Risk of bias was assessed by two review authors and the risk of bias table was completed for all studies in the 2010 update. Sensitivity analysis for low risk of bias studies, studies including only first time wheezers and studies including only infants less or equal to 12 months of age was completed in the 2010 update.

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.