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Endovascular versus open surgical repair for complicated chronic type B aortic dissection

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Appendices

Appendix 1. CENTRAL search strategy

#1

MESH DESCRIPTOR Aortic Aneurysm EXPLODE ALL TREES

#2

MESH DESCRIPTOR Aneurysm, Dissecting

#3

MESH DESCRIPTOR Aortic Rupture EXPLODE ALL TREES

#4

MESH DESCRIPTOR Aorta EXPLODE ALL TREES WITH QUALIFIERS SU

#5

MESH DESCRIPTOR Aneurysm, Ruptured

#6

(aort* near4 (aneurys* or dissect* or ruptur* or trauma* or tear* or split*)):TI,AB,KY

#7

malperfusion:TI,AB,KY

#8

(Type B near3 dissect*):TI,AB,KY

#9

(Stanford near3 dissect*):TI,AB,KY

#10

DeBakey:TI,AB,KY

#11

#1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10

#12

MESH DESCRIPTOR Endovascular Procedures EXPLODE ALL TREES

#13

MESH DESCRIPTOR Stents EXPLODE ALL TREES

#14

MESH DESCRIPTOR Vascular Surgical Procedures

#15

MESH DESCRIPTOR Blood Vessel Prosthesis EXPLODE ALL TREES

#16

MESH DESCRIPTOR Blood Vessel Prosthesis Implantation EXPLODE ALL TREES

#17

endovasc*:TI,AB,KY

#18

endostent*:TI,AB,KY

#19

endoluminal:TI,AB,KY

#20

endoprosthe*:TI,AB,KY

#21

(graft or endograft*):TI,AB,KY

#22

percutaneous*:TI,AB,KY

#23

stent*:TI,AB,KY

#24

(Palmaz or Zenith or Dynalink or Hemobahn or Luminex* or Memotherm or Wallstent):TI,AB,KY

#25

(Viabahn or Nitinol or Intracoil or Tantalum):TI,AB,KY

#26

EVAR:TI,AB,KY

#27

EVRAR:TI,AB,KY

#28

TEVAR:TI,AB,KY

#29

(vascular plug):TI,AB,KY

#30

#12 OR #13 OR #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23 OR #24 OR #25 OR #26 OR #27 OR #28 OR #29

#31

#11 AND #30

Table 1. Example of 'Summary of findings' table: endovascular versus open surgical repair for the treatment of complicated chronic type B aortic dissection

Endovascular repair compared with open surgical repair for complicated chronic type B aortic dissection

Patient or population: people with chronic complicated type B aortic dissection

Settings: hospital

Intervention: endovascular repair

Comparison: open surgical repair

Outcomes

Illustrative comparative risks* (95% CI)

Relative effect
(95% CI)

No of participants
(studies)

Quality of the evidence
(GRADE)

Comments

Assumed risk

Corresponding risk

Open surgical repair

Endovascular repair

Mortality: dissection‐related

(30‐day)

Neurological sequelae

(stroke, spinal cord ischaemia/paresis‐paralysis, vertebral insufficiency)

(1 year)

Morphological outcomes

(false lumen thrombosis, progression of dissection, aortic diameters)

(1 year)

Acute renal failure

(1 year)

Ischaemic symptoms

(visceral ischaemia, limb ischaemia)

(1 year)

Reintervention

(5 years)

Health‐related quality of life

(measured using validated quality of life scales as used by the included trials)

(1 year)

*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval.

GRADE Working Group grades of evidence
High quality: further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: we are very uncertain about the estimate.

Figures and Tables -
Table 1. Example of 'Summary of findings' table: endovascular versus open surgical repair for the treatment of complicated chronic type B aortic dissection